Production of cytotoxic factor by peripheral blood mononuclear cells (PBMC) in patients with dengue haemorrhagic fever

Clinical and Experimental Immunology

Volumn 112, Issue 3, 1998, Pages 477-481

  Agarwal, R ^a   Chaturvedi, U C ^a,b   Misra, A ^a   Mukerjee, R ^a   Kapoor, S ^a   Nagar, R ^a   Tandon, R ^a   Mathur, A ^a  

^a KING GEORGE'S MEDICAL UNIVERSITY   (India)

^b KUWAIT UNIVERSITY   (Kuwait)

Author keywords

Cytokine; Cytotoxic factor; Dengue haemorrhagic fever; Dengue virus

Indexed keywords

CD4 ANTIGEN; CYTOTOXIC FACTOR;

ARTICLE; CONTROLLED STUDY; DENGUE; DOT HYBRIDIZATION; ENZYME LINKED IMMUNOSORBENT ASSAY; FLUORESCENT ANTIBODY TECHNIQUE; HELPER CELL; HUMAN; HUMAN CELL; MAJOR CLINICAL STUDY; MONONUCLEAR CELL; PRIORITY JOURNAL;

CYTOKINES; DENGUE HEMORRHAGIC FEVER; ENZYME-LINKED IMMUNOSORBENT ASSAY; HUMANS; IMMUNOBLOTTING; LEUKOCYTES, MONONUCLEAR; RNA, MESSENGER;

EID: 0031860234     PISSN: 00099104     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2249.1998.00598.x     Document Type: Article

References (18)

1. Chaturvedi UC, Bhargava A, Mathur A. Production of cytotoxic factor in the spleen of dengue virus infected mice. Immunol 1980; 40:665-71.
2. Mukerjee R, Chaturvedi UC, Vaughn DW, Kalayanarooj S. Purification and pathogenicity of the cytotoxic factor from the cases of dengue haemorrhagic fever. Curr Sci 1997; 72:494-501.
3. Mukerjee R, Chaturvedi UC. Cytokine antagonism by active vaccination. Cur Sci 1995; 69:900-2.
4. Khanna M, Chaturvedi UC, Sharma MC, Pandey VC, Mathur A. Increased capillary permeability mediated by a dengue virus-induced lymphokine. Immunol 1990; 69:449-53.
5. Khanna M, Chaturvedi UC. Purification and amino-terminal sequence of the dengue virus-induced cytotoxic factor. Int J Exp Pathol 1992; 73:43-49.
6. Chaturvedi UC, Gulati L, Mathur A. Inhibition of E-rosettes formation and phagocytosis by human blood leucocytes after treatment with dengue virus-induced cytotoxic factor. Immunol 1982; 45:679-84.
7. Chaturvedi UC, Dhawan R, Khanna M, Mathur A. Breakdown of the blood-brain barrier during dengue virus infection of mice. J Gen Virol 1991; 72:859-66.
8. Mukerjee R, Chaturvedi UC. ELISA for detection of dengue virus-induced cytokine and its antibody. Ind J Exp Biol 1997; 35:225-31.
9. Mukerjee R, Chaturvedi UC, Dhawan R. Dengue virus-induced cytotoxic factor: production by peripheral blood leucocytes in vitro. Clin Exp Immunol 1995; 102:262-7.
10. Sander B, Andersson J, Andersson U. Assessment of cytokines by immunofluorescence and the paraformaldehyde-saponin procedure. Immunol Rev 1991; 119:65-93.
11. Nimmannitya S. Clinical manifestations of dengue/dengue haemorrhagic fever. In: Thongcharoen P, ed. Dengue/dengue haemorrhagic fever. New Delhi: WHO-SEARO, 1993:48-54.
12. Trizio D, Cudkowicz G. Separation of T and B lymphocytes by nylon wool columns: evaluation of efficacy by functional assays in vivo. J Immunol 1974; 113:1093-7.
13. Khare M, Chaturvedi UC. Transmission of dengue virus-specific suppressor signal depends on the presence of calcium. Indian J Med Res 1995; 102:1-8.
14. Chomczynski P, Sacchi N. Single step method of RNA isolation by acid guanidinium thiocyanate phenol chloroform extraction. Anal Biochem 1987; 162:156-9.
15. Gardner PS, McQuillin J. Rapid virus diagnosis. In: Applications of Immunofluorescence, 2nd edn. London: Butterworths, 1981:56-91.
16. Navikas V, Link J, Wahren B, Persson CH, Link H. Increased levels of interferon-gamma (IFN-γ), IL-4 and transforming growth factor-beta (TGF-/3) mRNA expressing blood mononuclear cells in human HIV infection. Clin Exp Immunol 1994; 96:59-63.
17. Agarwal R, Chaturvedi UC, Misra A, Kapoor S, Nagar R, Tandon R. CD4 positive T cells produce cytotoxic factor in cases of dengue haemorrhagic fever. Curr Sci 1998; 74:237-9.
18. Schauer U, Jung T, Krug N, Frew A. Measurement of intracellular cytokines. Immunol Today 1996; 17:305-6.