Intracellular Mg2+ regulates ADP phosphorylation and adenine nucleotide synthesis in human erythrocytes

American Journal of Physiology - Endocrinology and Metabolism

Volumn 274, Issue 5 37-5, 1998, Pages

  Page, Sarah ^a   Salem, Michael ^a   Laughlin, Maren R ^a  

^a GEORGE WASHINGTON UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

A 23187; Adenosine 5' triphosphate; Carbon 13 nuclear magnetic resonance; Glycolysis; Metabolic regulation; Pentose phosphate pathway

Indexed keywords

6 PHOSPHOFRUCTOKINASE; ADENINE NUCLEOTIDE; ADENOSINE DIPHOSPHATE; MAGNESIUM; RIBOSE 5 PHOSPHATE; GLUCOSE; GLUCOSE 6 PHOSPHATE;

ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; ERYTHROCYTE; GLUCOSE INTAKE; GLYCOLYSIS; HUMAN; HUMAN CELL; METABOLIC REGULATION; NUCLEOTIDE METABOLISM; PENTOSE PHOSPHATE CYCLE; PHOSPHORUS NUCLEAR MAGNETIC RESONANCE; PHOSPHORYLATION; PRIORITY JOURNAL; BIOSYNTHESIS; INTRACELLULAR MEMBRANE; METABOLISM; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PHYSIOLOGY;

ADENINE NUCLEOTIDES; ADENOSINE DIPHOSPHATE; ERYTHROCYTES; GLUCOSE; GLUCOSE-6-PHOSPHATE; HUMANS; INTRACELLULAR MEMBRANES; MAGNESIUM; MAGNETIC RESONANCE SPECTROSCOPY; PENTOSE PHOSPHATE PATHWAY; PHOSPHOFRUCTOKINASE-1; PHOSPHORYLATION;

EID: 0031859920     PISSN: 01931849     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpendo.1998.274.5.e920     Document Type: Article

References (29)

1. Aglio, L. S., G. G. Stanford, R. Maddi, J. L. Boyd, S. Nussbaum, and B. Chernow. Hypomagnesemia is common following cardiac surgery. J. Cardiothorac. Vasc. Anesth. 5: 201-208, 1991.
2. Elin, R. J. Magnesium content of mononuclear blood cells. Clin. Chem. 31: 377-380, 1985.
3. England, M. R., G. Gordon, M. Salem, and B. Chernow. Magnesium administration and dysrhythmias after cardiac surgery. JAMA 268: 2395-2402, 1992.
4. Fell, D. Understanding the Control of Metabolism. London: Portland Press, 1997.
5. Frenkel, E. J., M. Graziani, and H. J. Schatzmann. ATP requirement of the sodium-dependent magnesium extrusion from human red blood cells. J. Physiol. (Lond.) 414: 385-397, 1989.
6. Gerber, G., H. Preissler, R. Heinrich, and S. M. Rapoport. Hexokinase of human erythrocytes. Eur. J. Biochem. 45: 39-52, 1974.
7. Gerlach, E., J. Duhm, and B. Deuticke. In: Red Cell Metabolism and Function, edited by G. J. Brewer. New York: Plenum, 1970, p. 155-174.
8. Grimes, A. J. Anaerobic Glycolysis in Human Red Cell Metabolism. Oxford: Blackwell, 1980, p. 192-258.
9. 31P NMR. J. Biol. Chem. 253: 6172-6176, 1978.
10. Harris, M. N. E., A. Crowther, R. A. Jupp, and C. Aps. Magnesium and coronary revascularization. Br. J. Anaesth. 60: 779-783, 1988.
11. Heinrich, P. C., H. Steffen, P. Jauser, and O. Wiss. Studies on the reconstitution of apotransketolase with thiamin pyrophosphate and analogs of the coenzyme. Eur. J. Biochem. 30: 533-541, 1972.
12. Johnson, R. M., Y. Ravindranath, M. El-Alfy, and G. Goyette. Oxidant damage to erythrocyte membrane in G-6-P dehydrogenase deficiency. Correlation with in vivo reduced glutathione concentration and membrane protein oxidation. Blood 83: 1117-1123, 1994.
13. Laughlin, M. R., W. A. Petit, J. M. Dizon, R. G. Shulman, and E. J. Barrett. NMR measurements of in vivo myocardial glycogen metabolism. J. Biol. Chem. 263: 2285-2291, 1988.
14. Laughlin, M. R., and D. Thompson. The regulatory role for magnesium in glycolytic flux of the human erythrocyte. J. Biol. Chem. 271: 28977-28983, 1996.
15. Lohr, G. W., and H. D. Waller. Glucose-6-phosphate dehydrogenase. In: The Enzymes, edited by P.D. Boyer. New York: Academic, 1963, p. 636-641.
16. Minakami, S., and H. Yoshikawa. Studies on erythrocyte glycolysis. J. Biochem. 59: 145-152, 1966.
17. Otto, M., R. Heinrich, B. Kuhn, and G. Jacobasch. A mathematical model for the influence of F-6-P, ATP, potassium, ammonium and magnesium on the PFK from rat erythrocytes. Eur. J. Biochem. 49: 169-178, 1974.
18. 31P-NMR spectroscopy. Biochim. Biophys. Acta 1010: 294-303, 1989.
19. Palsson, B. O., A. Narang, and A. Joshi. Computer model of human erythrocyte metabolism. In: The Red Cell: Seventh Annual Arbor Conference edited by G. J. Brewer. New York: Liss, 1989, p. 133-154.
20. Ponce, J., S. Roth, and D. R. Harkness. Kinetic studies on the inhibition of glycolytic kinases of human erythrocytes by 2,3-diphosphogluconic acid. Biochim. Biophys. Acta 250: 63-74, 1971.
21. Rude, R. K., A Stephen, and J. Nadler. Determination of red blood cell intracellular free magnesium by NMR as an assessment of magnesium depletion. Magnes. Trace Elem. 10: 117-121, 1991-1992.
22. Ryzen, E., P. W. Wagers, and F. R. Singer. Magnesium deficiency in a medical ICU population. Crit. Care Med. 13: 14-21, 1985.
23. Salem, M., R. Munoz, and B. Chernow. Hypomagnesemia in critical illness. Crit. Care Clin. 7: 225-252, 1991.
24. Schlag, G., and H. Redl. Pathophysiology of Shock, Sepsis and Organ Failure. Berlin: Springer-Verlag, 1993.
25. Schrader, M. C., C. J. Eskey, V. Simplaceanu, and C. Ho. A carbon-13 nuclear magnetic resonance investigation of the metabolic fluxes associated with glucose metabolism in human erythrocytes. Biochim. Biophys. Acta 1182: 162-178, 1993.
26. Thorburn, D., and P. Kuchel. Regulation of the human erythrocyte hexose-monophosphate shunt under conditions of oxidative stress. Eur. J. Biochem. 150: 371-386, 1985.
27. Veronese, F. M., E. Boccu, A. Fontana, C. A. Benassi, and E. Scoffone. Isolation and some properties of 6-phosphogluconate dehydrogenase from Bacillus stearothermophilus. Biochim. Biophys. Acta 334: 31-44, 1974.
28. 2+ in vascular smooth muscle cells. Pflügers Arch. 421: 391-393, 1992.
29. Zimmer, H.-G., R. Bunger, H. Koschine, and G. Steinkopff. Rapid stimulation of the hexose monophosphate shunt in the isolated perfused rat heart: possible involvement of oxidized glutathione. J. Mol. Cell. Cardiol. 13: 531-535, 1981.