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Volumn 6, Issue 2, 1998, Pages 95-107

Pharmacology of benzydamine

Author keywords

Benzydamine; NSAIDs

Indexed keywords

ACETYLSALICYLIC ACID; ANTIINFLAMMATORY AGENT; ARACHIDONIC ACID; BENZYDAMINE; CYTOKINE; HISTAMINE; NONSTEROID ANTIINFLAMMATORY AGENT; PROSTAGLANDIN; TUMOR NECROSIS FACTOR ALPHA;

EID: 0031859436     PISSN: 09254692     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10787-998-0026-0     Document Type: Review
Times cited : (62)

References (57)
  • 1
    • 0014048281 scopus 로고
    • Toxicology of benzydamine
    • 1. B Silvestrini P Scorza Barcellona A Garau B Catanese 1967 Toxicology of benzydamine Toxicol Appl Pharmacol 10 148 59 6031923 10.1016/0041-008X(67)90136-6 1:CAS:528:DyaF2sXosVGqug%3D%3D Silvestrini B, Scorza Barcellona P, Garau A, Catanese B. Toxicology of benzydamine. Toxicol Appl Pharmacol. 1967;10:148–59.
    • (1967) Toxicol Appl Pharmacol , vol.10 , pp. 148-59
    • Silvestrini, B1    Scorza Barcellona, P2    Garau, A3    Catanese, B4
  • 2
    • 85121076526 scopus 로고    scopus 로고
    • 2. C Hansch PG Sammes JB Taylor 1990 CJ Drayton Comprehensive Medicinal Chemistry, Volume 6 Pergamon Press Oxford 309 309 Hansch C, Sammes PG, Taylor JB. In: Drayton CJ, ed. Comprehensive Medicinal Chemistry, Volume 6. Oxford: Pergamon Press; 1990:309.
  • 3
    • 0029918867 scopus 로고    scopus 로고
    • Spectroscopic characterization of benzdazac and benzydamine: possible photochemical modes of action
    • 3. JM Jez JM Vanderkooi AM Laties 1996 Spectroscopic characterization of benzdazac and benzydamine: possible photochemical modes of action Biochem Biophys Res Commun 221 266 70 8619844 10.1006/bbrc.1996.0584 1:CAS:528:DyaK28XisVaht7w%3D Jez JM, Vanderkooi JM, Laties AM. Spectroscopic characterization of benzdazac and benzydamine: possible photochemical modes of action. Biochem Biophys Res Commun. 1996;221:266–70.
    • (1996) Biochem Biophys Res Commun , vol.221 , pp. 266-70
    • Jez, JM1    Vanderkooi, JM2    Laties, AM3
  • 4
    • 0025779711 scopus 로고
    • Pharmacokinetics of benzydamine after intravenous, oral, and topical doses to human subjects
    • 4. GA Baldock RR Brodie LF Chasseaud T Taylor LM Walmsley B Catanese 1991 Pharmacokinetics of benzydamine after intravenous, oral, and topical doses to human subjects Biopharm Drug Dispos 12 481 92 1932611 10.1002/bdd.2510120702 1:CAS:528:DyaK3MXmt1aksbs%3D Baldock GA, Brodie RR, Chasseaud LF, Taylor T, Walmsley LM, Catanese B. Pharmacokinetics of benzydamine after intravenous, oral, and topical doses to human subjects. Biopharm Drug Dispos. 1991;12:481–92.
    • (1991) Biopharm Drug Dispos , vol.12 , pp. 481-92
    • Baldock, GA1    Brodie, RR2    Chasseaud, LF3    Taylor, T4    Walmsley, LM5    Catanese, B6
  • 5
    • 0023197809 scopus 로고
    • Pharmacokinetics of benzydamine
    • 5. RD Schoenwald T Kumakura B Catanese 1987 Pharmacokinetics of benzydamine Int J Tiss React 9 9 7 Schoenwald RD, Kumakura T, Catanese B. Pharmacokinetics of benzydamine. Int J Tiss React. 1987;9:9–7.
    • (1987) Int J Tiss React , vol.9 , pp. 9-7
    • Schoenwald, RD1    Kumakura, T2    Catanese, B3
  • 6
    • 0014180903 scopus 로고
    • Buccal absorption of basic drugs and its application as an in vivo model of passive drug transfer through lipid membranes
    • 6. AH Beckett EJ Triggs 1967 Buccal absorption of basic drugs and its application as an in vivo model of passive drug transfer through lipid membranes J Pharm Pharmacol 19 31S 41S 4383854 Beckett AH, Triggs EJ. Buccal absorption of basic drugs and its application as an in vivo model of passive drug transfer through lipid membranes. J Pharm Pharmacol. 1967;19:31S-41S.
    • (1967) J Pharm Pharmacol , vol.19 , pp. 31S-41S
    • Beckett, AH1    Triggs, EJ2
  • 7
    • 0014477972 scopus 로고
    • Buccal absorption and other properties of pharmacokinetic importance of imipramine and its metabolites
    • 7. MH Bickel HJ Weder 1969 Buccal absorption and other properties of pharmacokinetic importance of imipramine and its metabolites J Pharm Pharmacol 21 160 8 4388211 1:CAS:528:DyaF1MXpsFSqsw%3D%3D Bickel MH, Weder HJ. Buccal absorption and other properties of pharmacokinetic importance of imipramine and its metabolites. J Pharm Pharmacol. 1969;21:160–8.
    • (1969) J Pharm Pharmacol , vol.21 , pp. 160-8
    • Bickel, MH1    Weder, HJ2
  • 8
    • 0022255879 scopus 로고
    • Pharmacokinetics of benzydamine
    • 8. LF Chasseaud B Catanese 1985 Pharmacokinetics of benzydamine Int J Tiss React 7 195 204 1:CAS:528:DyaL2MXlvVyqsbw%3D Chasseaud LF, Catanese B. Pharmacokinetics of benzydamine. Int J Tiss React. 1985;7:195–204.
    • (1985) Int J Tiss React , vol.7 , pp. 195-204
    • Chasseaud, LF1    Catanese, B2
  • 9
    • 0016281103 scopus 로고
    • Percutaneous absorption of benzydamine in guinea pig and man
    • 9. K Andersson H Larsson 1974 Percutaneous absorption of benzydamine in guinea pig and man Arzneimittelforschung 24 1686 8 4479782 1:CAS:528:DyaE2MXhs1ClsbY%3D Andersson K, Larsson H. Percutaneous absorption of benzydamine in guinea pig and man. Arzneimittelforschung. 1974;24:1686–8.
    • (1974) Arzneimittelforschung , vol.24 , pp. 1686-8
    • Andersson, K1    Larsson, H2
  • 10
    • 0014282744 scopus 로고
    • Researches on the topical activity of benzydamine
    • 10. R Lisciani P Scorza Barcellona B Silvestrini 1968 Researches on the topical activity of benzydamine Eur J Pharmacol 3 157 62 5666012 10.1016/0014-2999(68)90069-1 1:CAS:528:DyaF1cXktFOrtb8%3D Lisciani R, Scorza Barcellona P, Silvestrini B. Researches on the topical activity of benzydamine. Eur J Pharmacol. 1968;3:157–62.
    • (1968) Eur J Pharmacol , vol.3 , pp. 157-62
    • Lisciani, R1    Scorza Barcellona, P2    Silvestrini, B3
  • 11
    • 0013987582 scopus 로고
    • A method for the determination of 1-benzyl-3[3′-(dimethylamino) propoxy]-1H-indazole (benzydamine) in rat tissues
    • 11. E Giacalone L Valzelli 1966 A method for the determination of 1-benzyl-3[3′-(dimethylamino) propoxy]-1H-indazole (benzydamine) in rat tissues Med Pharmacol Exp 15 102 6 1:CAS:528:DyaF28XltVagtLs%3D Giacalone E, Valzelli L. A method for the determination of 1-benzyl-3[3′-(dimethylamino) propoxy]-1H-indazole (benzydamine) in rat tissues. Med Pharmacol Exp. 1966;15:102–6.
    • (1966) Med Pharmacol Exp , vol.15 , pp. 102-6
    • Giacalone, E1    Valzelli, L2
  • 12
    • 0018614027 scopus 로고
    • In vivo metabolism and anti-inflammatory activity of benzydamine hydrochloride in rats treated with carrageenin
    • 12. S Kataoka K Nishimura T Naito 1979 In vivo metabolism and anti-inflammatory activity of benzydamine hydrochloride in rats treated with carrageenin Chem Pharm Bull (Tokyo) 27 2890 903 1:CAS:528:DyaL3cXht1Wnu70%3D Kataoka S, Nishimura K, Naito T. In vivo metabolism and anti-inflammatory activity of benzydamine hydrochloride in rats treated with carrageenin. Chem Pharm Bull (Tokyo). 1979;27:2890–903.
    • (1979) Chem Pharm Bull (Tokyo) , vol.27 , pp. 2890-903
    • Kataoka, S1    Nishimura, K2    Naito, T3
  • 13
    • 0014544474 scopus 로고
    • Erythrocyte membrane stabilization and protein binding of some anti-inflammatory drugs and of deoxycholic acid
    • 13. B Catanese R Lisciani D Piccinelli 1969 Erythrocyte membrane stabilization and protein binding of some anti-inflammatory drugs and of deoxycholic acid Biochem Pharmacol 18 1707 10 5806111 10.1016/0006-2952(69)90160-9 1:CAS:528:DyaF1MXks12jtbs%3D Catanese B, Lisciani R, Piccinelli D. Erythrocyte membrane stabilization and protein binding of some anti-inflammatory drugs and of deoxycholic acid. Biochem Pharmacol. 1969;18:1707–10.
    • (1969) Biochem Pharmacol , vol.18 , pp. 1707-10
    • Catanese, B1    Lisciani, R2    Piccinelli, D3
  • 14
    • 0018726360 scopus 로고
    • Enhanced uptake of actinomycin D in cultured mammalian cells by the anti-inflammatory non-steroidal drug benzydamine
    • 14. A Benedetto A Cassone C Amici E Garaci 1979 Enhanced uptake of actinomycin D in cultured mammalian cells by the anti-inflammatory non-steroidal drug benzydamine Biochem Pharmacol 28 2723 8 115474 10.1016/0006-2952(79)90554-9 1:CAS:528:DyaL3cXoslynsQ%3D%3D Benedetto A, Cassone A, Amici C, Garaci E. Enhanced uptake of actinomycin D in cultured mammalian cells by the anti-inflammatory non-steroidal drug benzydamine. Biochem Pharmacol. 1979;28:2723–8.
    • (1979) Biochem Pharmacol , vol.28 , pp. 2723-8
    • Benedetto, A1    Cassone, A2    Amici, C3    Garaci, E4
  • 15
    • 85121077762 scopus 로고
    • Studies on the absorption and elimination of benzydamine in the mouse, rat, dog and man
    • 15. B Catanese A Grasso B Silvestrini 1985 Studies on the absorption and elimination of benzydamine in the mouse, rat, dog and man Arzneimittelforschung 35 634 5 Catanese B, Grasso A, Silvestrini B. Studies on the absorption and elimination of benzydamine in the mouse, rat, dog and man. Arzneimittelforschung. 1985;35:634–5.
    • (1985) Arzneimittelforschung , vol.35 , pp. 634-5
    • Catanese, B1    Grasso, A2    Silvestrini, B3
  • 16
    • 0021914302 scopus 로고
    • Metabolism of benzydamine
    • 16. C Köppel Tenczer 1985 Metabolism of benzydamine Arzneimittelforschung 35 634 5 4039589 Köppel C, Tenczer. Metabolism of benzydamine. Arzneimittelforschung. 1985;35:634–5.
    • (1985) Arzneimittelforschung , vol.35 , pp. 634-5
    • Köppel, C1    Tenczer2
  • 17
    • 0029874638 scopus 로고    scopus 로고
    • Antibacterial activity of benzydamine and antibiotic-benzydamine combinations against multifold resistant clinical isolates
    • 17. NH Fanaki MA El-Nakeeb 1996 Antibacterial activity of benzydamine and antibiotic-benzydamine combinations against multifold resistant clinical isolates Arzneimittelforschung 46 320 3 8901158 1:CAS:528:DyaK28Xis1Sis7s%3D Fanaki NH, El-Nakeeb MA. Antibacterial activity of benzydamine and antibiotic-benzydamine combinations against multifold resistant clinical isolates. Arzneimittelforschung. 1996;46:320–3.
    • (1996) Arzneimittelforschung , vol.46 , pp. 320-3
    • Fanaki, NH1    El-Nakeeb, MA2
  • 18
    • 0027054521 scopus 로고
    • Antimicrobial activity of benzydamine, a non-steroid anti-inflammatory agent
    • 18. NH Fanaki MA el-Nakeeb 1992 Antimicrobial activity of benzydamine, a non-steroid anti-inflammatory agent J Chemother 4 347 52 1287137 1:CAS:528:DyaK3sXkt1CntLo%3D Fanaki NH, el-Nakeeb MA. Antimicrobial activity of benzydamine, a non-steroid anti-inflammatory agent. J Chemother. 1992;4:347–52.
    • (1992) J Chemother , vol.4 , pp. 347-52
    • Fanaki, NH1    el-Nakeeb, MA2
  • 19
    • 0003792776 scopus 로고
    • The pharmacology of benzydamine
    • 19. SK White 1988 The pharmacology of benzydamine Res Clin Forums 10 8 23 White SK. The pharmacology of benzydamine. Res Clin Forums. 1988;10:8–23.
    • (1988) Res Clin Forums , vol.10 , pp. 8-23
    • White, SK1
  • 20
    • 0014715190 scopus 로고
    • Action comparee de six anti-inflammatory non steroidiques
    • 20. JR Boissier JM Lwoff F Hertz 1970 Action comparee de six anti-inflammatory non steroidiques Therapie 25 43 60 5436803 1:CAS:528:DyaE3cXktFejsbg%3D Boissier JR, Lwoff JM, Hertz F. Action comparee de six anti-inflammatory non steroidiques. Therapie. 1970;25:43–60.
    • (1970) Therapie , vol.25 , pp. 43-60
    • Boissier, JR1    Lwoff, JM2    Hertz, F3
  • 21
    • 0016692386 scopus 로고
    • Effects of vasoactive agents on the canine forelimb venous perfusion preparation and their modification by anti-inflammatory drugs
    • 21. Y Yamatake H Kato K Takagi 1975 Effects of vasoactive agents on the canine forelimb venous perfusion preparation and their modification by anti-inflammatory drugs Jpn J Pharmacol 25 129 39 1:CAS:528:DyaE2MXltVyqtrg%3D Yamatake Y, Kato H, Takagi K. Effects of vasoactive agents on the canine forelimb venous perfusion preparation and their modification by anti-inflammatory drugs. Jpn J Pharmacol. 1975;25:129–39.
    • (1975) Jpn J Pharmacol , vol.25 , pp. 129-39
    • Yamatake, Y1    Kato, H2    Takagi, K3
  • 22
    • 0015138278 scopus 로고
    • Clinical evaluation of topical benzydamine in traumatology
    • 22. S Fantato M Gregorio De 1971 Clinical evaluation of topical benzydamine in traumatology Arzneimittelforschung 21 1530 3 4945249 1:STN:280:DyaE387gtVejsQ%3D%3D Fantato S, De Gregorio M. Clinical evaluation of topical benzydamine in traumatology. Arzneimittelforschung. 1971;21:1530–3.
    • (1971) Arzneimittelforschung , vol.21 , pp. 1530-3
    • Fantato, S1    Gregorio, M2
  • 23
    • 0017669209 scopus 로고
    • A double blind clinical study with benzydamine 3% on soft tissue injuries in an occupational health centre
    • 23. DS Chatterjee 1977 A double blind clinical study with benzydamine 3% on soft tissue injuries in an occupational health centre J Int Med Res 5 450 8 338395 1:STN:280:DyaE1c%2FmsFSjsA%3D%3D Chatterjee DS. A double blind clinical study with benzydamine 3% on soft tissue injuries in an occupational health centre. J Int Med Res. 1977;5:450–8.
    • (1977) J Int Med Res , vol.5 , pp. 450-8
    • Chatterjee, DS1
  • 24
    • 0018622515 scopus 로고
    • Benzydamine oral rinse for sore throat
    • 24. J Froom V Boisseau 1979 Benzydamine oral rinse for sore throat Curr Ther Res 26 856 61 Froom J, Boisseau V. Benzydamine oral rinse for sore throat. Curr Ther Res. 1979;26:856–61.
    • (1979) Curr Ther Res , vol.26 , pp. 856-61
    • Froom, J1    Boisseau, V2
  • 25
    • 0019948758 scopus 로고
    • A controlled study of benzydamine oral rinse (“Difflam”) in general practice
    • 25. MW Whiteside 1982 A controlled study of benzydamine oral rinse (“Difflam”) in general practice Curr Med Res Opin 8 188 90 7128190 1:STN:280:DyaL3s%2Fis1erug%3D%3D Whiteside MW. A controlled study of benzydamine oral rinse (“Difflam”) in general practice. Curr Med Res Opin. 1982;8:188–90.
    • (1982) Curr Med Res Opin , vol.8 , pp. 188-90
    • Whiteside, MW1
  • 26
    • 0022972035 scopus 로고
    • Benzydamine hydrochloride in prevention and management of pain in oral mucositis associated with radiation therapy
    • 26. JB Epstein P Stevenson-Moore 1986 Benzydamine hydrochloride in prevention and management of pain in oral mucositis associated with radiation therapy Oral Surg Oral Med Oral Pathol 62 145 8 3528978 10.1016/0030-4220(86)90035-6 1:STN:280:DyaL28zht1ejsg%3D%3D Epstein JB, Stevenson-Moore P. Benzydamine hydrochloride in prevention and management of pain in oral mucositis associated with radiation therapy. Oral Surg Oral Med Oral Pathol. 1986;62:145–8.
    • (1986) Oral Surg Oral Med Oral Pathol , vol.62 , pp. 145-8
    • Epstein, JB1    Stevenson-Moore, P2
  • 27
    • 0021954088 scopus 로고
    • Benzydamine HCl in the management of chemotherapy-induced mucositis. I. Pilot study
    • 27. ST Sonis ST Clairmont PB Lockhart SF Connolly 1985 Benzydamine HCl in the management of chemotherapy-induced mucositis. I. Pilot study J Oral Med 40 67 71 3858465 1:STN:280:DyaL2M3htVansw%3D%3D Sonis ST, Clairmont ST, Lockhart PB, Connolly SF. Benzydamine HCl in the management of chemotherapy-induced mucositis. I. Pilot study. J Oral Med. 1985;40:67–71.
    • (1985) J Oral Med , vol.40 , pp. 67-71
    • Sonis, ST1    Clairmont, ST2    Lockhart, PB3    Connolly, SF4
  • 28
    • 0024802994 scopus 로고
    • Pain relief after tonsillectomy
    • 28. A Valijan 1989 Pain relief after tonsillectomy Anaesthesia 44 990 1 2619026 10.1111/j.1365-2044.1989.tb09205.x 1:STN:280:DyaK3c7ksFCrug%3D%3D Valijan A. Pain relief after tonsillectomy. Anaesthesia. 1989;44:990–1.
    • (1989) Anaesthesia , vol.44 , pp. 990-1
    • Valijan, A1
  • 29
    • 0023139567 scopus 로고
    • Clinical evaluation of benzydamine, chlorohexidine, and placebo mouthwashes in the management of recurrent aphthous stomatis
    • 29. RW Matthews CM Scully BGH Levers 1987 Clinical evaluation of benzydamine, chlorohexidine, and placebo mouthwashes in the management of recurrent aphthous stomatis Oral Surg Oral Med Oral Pathol 63 189 91 3469601 10.1016/0030-4220(87)90310-0 1:STN:280:DyaL2s7ksFKhtg%3D%3D Matthews RW, Scully CM, Levers BGH. Clinical evaluation of benzydamine, chlorohexidine, and placebo mouthwashes in the management of recurrent aphthous stomatis. Oral Surg Oral Med Oral Pathol. 1987;63:189–91.
    • (1987) Oral Surg Oral Med Oral Pathol , vol.63 , pp. 189-91
    • Matthews, RW1    Scully, CM2    Levers, BGH3
  • 30
    • 0018099933 scopus 로고
    • A clinical evaluation of benzydamine hydrochloride
    • 30. KMacD Hunter 1978 A clinical evaluation of benzydamine hydrochloride Aust Dent J 23 164 6 361026 1:STN:280:DyaE1M%2FktFejtQ%3D%3D Hunter KMacD. A clinical evaluation of benzydamine hydrochloride. Aust Dent J. 1978;23:164–6.
    • (1978) Aust Dent J , vol.23 , pp. 164-6
    • Hunter, KMacD1
  • 31
    • 0025449989 scopus 로고
    • Evaluation of benzydamine in treatment of secondary inflammation following extraction of third molars
    • 31. R Adame Sosa A Gomez Pedroso 1990 Evaluation of benzydamine in treatment of secondary inflammation following extraction of third molars Pract Odontol 11 29 31 2132273 1:STN:280:DyaK38%2FntlaksQ%3D%3D Adame Sosa R, Gomez Pedroso A. Evaluation of benzydamine in treatment of secondary inflammation following extraction of third molars. Pract Odontol. 1990;11:29–31.
    • (1990) Pract Odontol , vol.11 , pp. 29-31
    • Adame Sosa, R1    Gomez Pedroso, A2
  • 32
    • 0024512533 scopus 로고
    • Effects of benzydamine on the rabbit’s eye reaction to surgical, physical and chemical stimuli
    • 32. L Tomazzoli MR Bonora L Luparini MG Durando V Ciolo L Bonomi 1989 Effects of benzydamine on the rabbit’s eye reaction to surgical, physical and chemical stimuli J Ocul Pharmacol 5 71 80 2715678 1:CAS:528:DyaL1MXktVSksrg%3D 10.1089/jop.1989.5.71 Tomazzoli L, Bonora MR, Luparini L, Durando MG, Ciolo V, Bonomi L. Effects of benzydamine on the rabbit’s eye reaction to surgical, physical and chemical stimuli. J Ocul Pharmacol. 1989;5:71–80.
    • (1989) J Ocul Pharmacol , vol.5 , pp. 71-80
    • Tomazzoli, L1    Bonora, MR2    Luparini, L3    Durando, MG4    Ciolo, V5    Bonomi, L6
  • 33
    • 0018665996 scopus 로고
    • On the mode of action and biochemical properties of anti-inflammatory drugs
    • 33. SA Saeed PA Kendall NM Butt HOJ Collier 1979 On the mode of action and biochemical properties of anti-inflammatory drugs Biochem Soc Trans 7 655 7 113266 1:CAS:528:DyaL3cXhsFarsA%3D%3D Saeed SA, Kendall PA, Butt NM, Collier HOJ. On the mode of action and biochemical properties of anti-inflammatory drugs. Biochem Soc Trans. 1979;7:655–7.
    • (1979) Biochem Soc Trans , vol.7 , pp. 655-7
    • Saeed, SA1    Kendall, PA2    Butt, NM3    Collier, HOJ4
  • 34
    • 0023183319 scopus 로고
    • Einfluss von benzydamin auf bildung ung interacktion von reaktiven sauerstoffspezies und die zyklo- und lipoxigenase
    • 34. R Müller-Peddinghaus M Wurl G Lenoir A Houben J Remacle 1987 Einfluss von benzydamin auf bildung ung interacktion von reaktiven sauerstoffspezies und die zyklo-und lipoxigenase Arzneimittelforschung 37 601 5 3040020 Müller-Peddinghaus R, Wurl M, Lenoir G, Houben A, Remacle J. Einfluss von benzydamin auf bildung ung interacktion von reaktiven sauerstoffspezies und die zyklo-und lipoxigenase. Arzneimittelforschung. 1987;37:601–5.
    • (1987) Arzneimittelforschung , vol.37 , pp. 601-5
    • Müller-Peddinghaus, R1    Wurl, M2    Lenoir, G3    Houben, A4    Remacle, J5
  • 35
    • 0022255002 scopus 로고
    • Aspects of the mechanisms of action of benzydamine
    • 35. G Segre S Hammarström 1985 Aspects of the mechanisms of action of benzydamine Int J Tiss React 7 187 93 1:CAS:528:DyaL2MXlvVyqsb8%3D Segre G, Hammarström S. Aspects of the mechanisms of action of benzydamine. Int J Tiss React. 1985;7:187–93.
    • (1985) Int J Tiss React , vol.7 , pp. 187-93
    • Segre, G1    Hammarström, S2
  • 36
    • 0004121625 scopus 로고
    • Pharmacology
    • 36. HP Rang MM Dale JM Ritter 1995 Pharmacology 3rd edn. Churchill Livingstone Edinburgh 230 230 Rang HP, Dale MM, Ritter JM. In: Pharmacology, 3rd edn. Edinburgh: Churchill Livingstone; 1995:230.
    • (1995) , pp. 230-230
    • Rang, HP1    Dale, MM2    Ritter, JM3
  • 37
    • 0023228034 scopus 로고
    • The action of benzydamine on phospholipase activation
    • 37. BM Löffler E Bohn B Hesse H Kunze 1987 The action of benzydamine on phospholipase activation Arzneimittelforschung 37 618 21 3619982 Löffler BM, Bohn E, Hesse B, Kunze H. The action of benzydamine on phospholipase activation. Arzneimittelforschung. 1987;37:618–21.
    • (1987) Arzneimittelforschung , vol.37 , pp. 618-21
    • Löffler, BM1    Bohn, E2    Hesse, B3    Kunze, H4
  • 38
    • 0017084547 scopus 로고
    • Prostaglandin endoperoxide and thromboxane generating systems and their selective inhibition
    • 38. S Moncada P Needleman S Bunting JR Vane 1976 Prostaglandin endoperoxide and thromboxane generating systems and their selective inhibition Prostaglandins 12 323 35 968048 10.1016/0090-6980(76)90014-9 1:CAS:528:DyaE28XlsFGnsrg%3D Moncada S, Needleman P, Bunting S, Vane JR. Prostaglandin endoperoxide and thromboxane generating systems and their selective inhibition. Prostaglandins. 1976;12:323–35.
    • (1976) Prostaglandins , vol.12 , pp. 323-35
    • Moncada, S1    Needleman, P2    Bunting, S3    Vane, JR4
  • 39
    • 0017763895 scopus 로고
    • Inhibitors of thromboxane synthase in human platelets
    • 39. U Diczfalusy S Hammarström 1977 Inhibitors of thromboxane synthase in human platelets FEBS Lett 82 107 10 10.1016/0014-5793(77)80896-X 1:CAS:528:DyaE1cXit1yl Diczfalusy U, Hammarström S. Inhibitors of thromboxane synthase in human platelets. FEBS Lett. 1977;82:107–10.
    • (1977) FEBS Lett , vol.82 , pp. 107-10
    • Diczfalusy, U1    Hammarström, S2
  • 40
    • 0023262811 scopus 로고
    • Antithrombotische wirking von benzydamin
    • 40. WCM Jansen 1987 Antithrombotische wirking von benzydamin Arzneimittelforschung 37 626 8 3619983 1:CAS:528:DyaL2sXksFWksbg%3D Jansen WCM. Antithrombotische wirking von benzydamin. Arzneimittelforschung. 1987;37:626–8.
    • (1987) Arzneimittelforschung , vol.37 , pp. 626-8
    • Jansen, WCM1
  • 41
    • 0015796477 scopus 로고
    • Quantitative determination of prostaglandins and malondialdehyde formed by the arachidonic oxygenase (prostaglandin synthetase) system of bovine seminal vesicle
    • 41. RJ Flower HS Cheung DW Cushman 1973 Quantitative determination of prostaglandins and malondialdehyde formed by the arachidonic oxygenase (prostaglandin synthetase) system of bovine seminal vesicle Prostaglandins 4 325 41 4783568 10.1016/0090-6980(73)90020-8 1:CAS:528:DyaE2cXmslKltw%3D%3D Flower RJ, Cheung HS, Cushman DW. Quantitative determination of prostaglandins and malondialdehyde formed by the arachidonic oxygenase (prostaglandin synthetase) system of bovine seminal vesicle. Prostaglandins. 1973;4:325–41.
    • (1973) Prostaglandins , vol.4 , pp. 325-41
    • Flower, RJ1    Cheung, HS2    Cushman, DW3
  • 42
    • 0017265675 scopus 로고
    • Effects of benzydamine on the lipolytic system of fat cells
    • 42. V Dinnendahl HD Peters PS Schönhöfer 1976 Effects of benzydamine on the lipolytic system of fat cells Biochem Pharmacol 25 299 303 178318 10.1016/0006-2952(76)90218-5 1:CAS:528:DyaE28XktFers70%3D Dinnendahl V, Peters HD, Schönhöfer PS. Effects of benzydamine on the lipolytic system of fat cells. Biochem Pharmacol. 1976;25:299–303.
    • (1976) Biochem Pharmacol , vol.25 , pp. 299-303
    • Dinnendahl, V1    Peters, HD2    Schönhöfer, PS3
  • 43
    • 0015509455 scopus 로고
    • Inhibition of amino sugar formation by several non-steroid anti-inflammatory agents
    • 43. M Akamatsu Y Miura 1972 Inhibition of amino sugar formation by several non-steroid anti-inflammatory agents Biochem Pharmacol 21 1991 3 4649346 10.1016/0006-2952(72)90012-3 1:CAS:528:DyaE38XkvFKku7k%3D Akamatsu M, Miura Y. Inhibition of amino sugar formation by several non-steroid anti-inflammatory agents. Biochem Pharmacol. 1972;21:1991–3.
    • (1972) Biochem Pharmacol , vol.21 , pp. 1991-3
    • Akamatsu, M1    Miura, Y2
  • 44
    • 0021885707 scopus 로고
    • Effect of benzydamine on exocytosis and respiratory burst in human neutrophils and mononuclear phagocytes
    • 44. M Baggiolini P Mauderli U Näf B Catanese 1985 Effect of benzydamine on exocytosis and respiratory burst in human neutrophils and mononuclear phagocytes Agents Actions 16 346 52 2996321 10.1007/BF01982871 1:CAS:528:DyaL2MXkvFyntrs%3D Baggiolini M, Mauderli P, Näf U, Catanese B. Effect of benzydamine on exocytosis and respiratory burst in human neutrophils and mononuclear phagocytes. Agents Actions. 1985;16:346–52.
    • (1985) Agents Actions , vol.16 , pp. 346-52
    • Baggiolini, M1    Mauderli, P2    Näf, U3    Catanese, B4
  • 45
    • 0030249568 scopus 로고    scopus 로고
    • Inhibition of inflammatory cytokine production and protection against endotoxin toxicity by benzydamine
    • 45. M Sironi P Pozzi N Polentarutti 1996 Inhibition of inflammatory cytokine production and protection against endotoxin toxicity by benzydamine Cytokines 8 710 16 10.1006/cyto.1996.0094 1:CAS:528:DyaK28Xmsl2ksbo%3D Sironi M, Pozzi P, Polentarutti N et al. Inhibition of inflammatory cytokine production and protection against endotoxin toxicity by benzydamine. Cytokines. 1996;8:710–16.
    • (1996) Cytokines , vol.8 , pp. 710-16
    • Sironi, M1    Pozzi, P2    Polentarutti, N3
  • 46
    • 0023122023 scopus 로고
    • The amplified chemiluminescence test to characterize antirheumatic drugs as oxygen radical scavengers
    • 46. R Müller-Peddinghaus M Wurl 1987 The amplified chemiluminescence test to characterize antirheumatic drugs as oxygen radical scavengers Biochem Pharmacol 36 1125 32 3032204 10.1016/0006-2952(87)90423-0 Müller-Peddinghaus R, Wurl M. The amplified chemiluminescence test to characterize antirheumatic drugs as oxygen radical scavengers. Biochem Pharmacol. 1987;36:1125–32.
    • (1987) Biochem Pharmacol , vol.36 , pp. 1125-32
    • Müller-Peddinghaus, R1    Wurl, M2
  • 47
    • 0017117419 scopus 로고
    • Inhibition of superoxide anion production in macrophages by anti-inflammatory drugs
    • 47. Y Oyanagui 1976 Inhibition of superoxide anion production in macrophages by anti-inflammatory drugs Biochem Pharmacol 25 1473 80 8043 10.1016/0006-2952(76)90063-0 1:CAS:528:DyaE28XltVekurk%3D Oyanagui Y. Inhibition of superoxide anion production in macrophages by anti-inflammatory drugs. Biochem Pharmacol. 1976;25:1473–80.
    • (1976) Biochem Pharmacol , vol.25 , pp. 1473-80
    • Oyanagui, Y1
  • 48
    • 0013944787 scopus 로고
    • Additional pharmacological studies on benzydamine
    • 48. B Silvestrini A Garau C Pozzatti V Cioli B Catanese 1966 Additional pharmacological studies on benzydamine Arch Int Pharmacodyn Ther 163 61 9 5970856 1:CAS:528:DyaF28XltVantro%3D Silvestrini B, Garau A, Pozzatti C, Cioli V, Catanese B. Additional pharmacological studies on benzydamine. Arch Int Pharmacodyn Ther. 1966;163:61–9.
    • (1966) Arch Int Pharmacodyn Ther , vol.163 , pp. 61-9
    • Silvestrini, B1    Garau, A2    Pozzatti, C3    Cioli, V4    Catanese, B5
  • 49
    • 0018170935 scopus 로고
    • Topical anaesthetic activity of benzydamine
    • 49. S Simard-Savoie D Forest 1978 Topical anaesthetic activity of benzydamine Curr Ther Res 6 734 5 Simard-Savoie S, Forest D. Topical anaesthetic activity of benzydamine. Curr Ther Res. 1978;6:734–5.
    • (1978) Curr Ther Res , vol.6 , pp. 734-5
    • Simard-Savoie, S1    Forest, D2
  • 50
    • 0022255736 scopus 로고
    • Review of pharmacological data on benzydamine
    • 50. V Cioli C Corradino P Scorza Barcellona 1985 Review of pharmacological data on benzydamine Int J Tiss React 8 205 13 Cioli V, Corradino C, Scorza Barcellona P. Review of pharmacological data on benzydamine. Int J Tiss React. 1985;8:205–13.
    • (1985) Int J Tiss React , vol.8 , pp. 205-13
    • Cioli, V1    Corradino, C2    Scorza Barcellona, P3
  • 51
    • 0029959501 scopus 로고    scopus 로고
    • Effects of local anaesthetics on carrageenan-evoked inflammatory nocioceptive processing in the rat
    • 51. J Buritova D Fletcher P Honore J-M Besson 1996 Effects of local anaesthetics on carrageenan-evoked inflammatory nocioceptive processing in the rat Br J Anaesth 77 645 52 8957983 1:CAS:528:DyaK2sXhvFeltg%3D%3D Buritova J, Fletcher D, Honore P, Besson J-M. Effects of local anaesthetics on carrageenan-evoked inflammatory nocioceptive processing in the rat. Br J Anaesth. 1996;77:645–52.
    • (1996) Br J Anaesth , vol.77 , pp. 645-52
    • Buritova, J1    Fletcher, D2    Honore, P3    Besson, J-M4
  • 52
    • 0030010936 scopus 로고    scopus 로고
    • Analgesic and anti-inflammatory effects of lignocaine-prilocaine (EMLA) cream in human burn injury
    • 52. JL Pedersen T Callesen S Moiniche H Kehlet 1996 Analgesic and anti-inflammatory effects of lignocaine-prilocaine (EMLA) cream in human burn injury Br J Anaesth 76 806 10 8679354 1:CAS:528:DyaK28XksFeisb8%3D Pedersen JL, Callesen T, Moiniche S, Kehlet H. Analgesic and anti-inflammatory effects of lignocaine-prilocaine (EMLA) cream in human burn injury. Br J Anaesth. 1996;76:806–10.
    • (1996) Br J Anaesth , vol.76 , pp. 806-10
    • Pedersen, JL1    Callesen, T2    Moiniche, S3    Kehlet, H4
  • 53
    • 0017367964 scopus 로고
    • Effects of tinoridine on stability of rat liver and kidney lysosomes and liver parenchymal cells
    • 53. K Goto M Hisadome H Imamura 1977 Effects of tinoridine on stability of rat liver and kidney lysosomes and liver parenchymal cells Biochem Pharmacol 26 11 18 576205 10.1016/0006-2952(77)90123-X 1:CAS:528:DyaE2sXhs1Ghtr4%3D Goto K, Hisadome M, Imamura H. Effects of tinoridine on stability of rat liver and kidney lysosomes and liver parenchymal cells. Biochem Pharmacol. 1977;26:11–18.
    • (1977) Biochem Pharmacol , vol.26 , pp. 11-18
    • Goto, K1    Hisadome, M2    Imamura, H3
  • 54
    • 0022607993 scopus 로고
    • Cinchocaine and amethocaine inhibit activation and activity of superoxide production of human neutrophils
    • 54. K Irita I Fujita S Takeshige S Minakami J Yoshitake 1986 Cinchocaine and amethocaine inhibit activation and activity of superoxide production of human neutrophils Br J Anaesth 58 639 45 3011043 10.1093/bja/58.6.639 1:CAS:528:DyaL28XktlGmtb8%3D Irita K, Fujita I, Takeshige S, Minakami S, Yoshitake J. Cinchocaine and amethocaine inhibit activation and activity of superoxide production of human neutrophils. Br J Anaesth. 1986;58:639–45.
    • (1986) Br J Anaesth , vol.58 , pp. 639-45
    • Irita, K1    Fujita, I2    Takeshige, S3    Minakami, S4    Yoshitake, J5
  • 55
    • 0030602898 scopus 로고    scopus 로고
    • Membrane stabilizing anti-oxidative interactions of propranolol and dexpropranolol with neutrophils
    • 55. R Anderson G Ramafi AJ Theron 1996 Membrane stabilizing anti-oxidative interactions of propranolol and dexpropranolol with neutrophils Biochem Pharmacol 52 341 9 8694859 10.1016/0006-2952(96)00212-2 1:CAS:528:DyaK28Xkt1Krt70%3D Anderson R, Ramafi G, Theron AJ. Membrane stabilizing anti-oxidative interactions of propranolol and dexpropranolol with neutrophils. Biochem Pharmacol. 1996;52:341–9.
    • (1996) Biochem Pharmacol , vol.52 , pp. 341-9
    • Anderson, R1    Ramafi, G2    Theron, AJ3
  • 56
    • 0023160761 scopus 로고
    • Inhibition of nonsteroidal anti-inflammatory drugs of superoxide production and granule enzyme release by polymorphonuclear leukocytes stimulated with immune complexes or formyl-methionyl-leucyl-phenylalanine
    • 56. TM Neal MC Vissers CC Winterbourn 1987 Inhibition of nonsteroidal anti-inflammatory drugs of superoxide production and granule enzyme release by polymorphonuclear leukocytes stimulated with immune complexes or formyl-methionyl-leucyl-phenylalanine Biochem Pharmacol 36 2511 17 3038127 10.1016/0006-2952(87)90524-7 1:CAS:528:DyaL2sXlt1Kks7w%3D Neal TM, Vissers MC, Winterbourn CC. Inhibition of nonsteroidal anti-inflammatory drugs of superoxide production and granule enzyme release by polymorphonuclear leukocytes stimulated with immune complexes or formyl-methionyl-leucyl-phenylalanine. Biochem Pharmacol. 1987;36:2511–17.
    • (1987) Biochem Pharmacol , vol.36 , pp. 2511-17
    • Neal, TM1    Vissers, MC2    Winterbourn, CC3
  • 57
    • 0023261672 scopus 로고
    • Inhibition of neutrophil-mediated degradation of isolated basement membrane collagen by nonsteroidal antiinflammatory drugs that inhibit degranulation
    • 57. TM Neal MC Vissers CC Winterbourn 1987 Inhibition of neutrophil-mediated degradation of isolated basement membrane collagen by nonsteroidal antiinflammatory drugs that inhibit degranulation Arthritis Rheum 30 908 13 3632731 10.1002/art.1780300810 1:CAS:528:DyaL2sXls1ynsbc%3D Neal TM, Vissers MC, Winterbourn CC. Inhibition of neutrophil-mediated degradation of isolated basement membrane collagen by nonsteroidal antiinflammatory drugs that inhibit degranulation. Arthritis Rheum. 1987;30:908–13.
    • (1987) Arthritis Rheum , vol.30 , pp. 908-13
    • Neal, TM1    Vissers, MC2    Winterbourn, CC3


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