메뉴 건너뛰기




Volumn 59, Issue 4, 1998, Pages 424-428

Intrahepatic modulation of portal pressure and its role in portal hypertension

Author keywords

Human cirrhosis; Intrahepatic vascular resistance; Intravital fluorescent microscopy; Laser Doppler flowmetry; Portal hypertension

Indexed keywords

CONFERENCE PAPER; FLUORESCENCE MICROSCOPY; LASER DOPPLER FLOWMETRY; LIVER CIRRHOSIS; PORTAL HYPERTENSION; PORTAL VEIN BLOOD PRESSURE; PRIORITY JOURNAL; VASCULAR RESISTANCE;

EID: 0031858338     PISSN: 00122823     EISSN: None     Source Type: Journal    
DOI: 10.1159/000007503     Document Type: Conference Paper
Times cited : (5)

References (58)
  • 1
    • 33750700881 scopus 로고    scopus 로고
    • A time-dependent balance between endothelins and nitric oxide regulating portal resistance after endotoxin
    • Pannen BH, Bauer M, Zhang JX, Robotham JL, Clemens MG: A time-dependent balance between endothelins and nitric oxide regulating portal resistance after endotoxin. Am J Physiol 1996;271:H1953-H1961.
    • (1996) Am J Physiol , vol.271
    • Pannen, B.H.1    Bauer, M.2    Zhang, J.X.3    Robotham, J.L.4    Clemens, M.G.5
  • 2
    • 3543007516 scopus 로고
    • Microcirculation in perfused liver
    • Ballet F, Thurman RG (eds): Paris, INSERM/Libbey
    • Huet PM, Semert M, Villeneuve JP, Willems B: Microcirculation in perfused liver; in Ballet F, Thurman RG (eds): Research in Perfused Liver. Paris, INSERM/Libbey, 1991, pp 321-337.
    • (1991) Research in Perfused Liver , pp. 321-337
    • Huet, P.M.1    Semert, M.2    Villeneuve, J.P.3    Willems, B.4
  • 3
    • 0344651715 scopus 로고    scopus 로고
    • Circulating body fluids
    • Ganong WF (ed): Norwalk, Appleton and Lange
    • Ganong WF: Circulating body fluids; in Ganong WF (ed): Review of Medical Physiology. Norwalk, Appleton and Lange, 1997, pp 468-493.
    • (1997) Review of Medical Physiology , pp. 468-493
    • Ganong, W.F.1
  • 5
    • 0028936263 scopus 로고
    • Lipoproteins and the liver sieve: The role of the fenestrated sinusoidal endothelium in lipoprotein metabolism, atherosclerosis, and cirrhosis
    • Fraser R, Dobbs BR, Rogers GW: Lipoproteins and the liver sieve: The role of the fenestrated sinusoidal endothelium in lipoprotein metabolism, atherosclerosis, and cirrhosis. Hepatology 1995;21:863-874.
    • (1995) Hepatology , vol.21 , pp. 863-874
    • Fraser, R.1    Dobbs, B.R.2    Rogers, G.W.3
  • 6
    • 0029025041 scopus 로고
    • In vivo microscopic assessment of hepatic microcirculation during liver allograft rejection in the rat
    • Kawano K, Bowers JL, Kruskal JB, Clouse ME: In vivo microscopic assessment of hepatic microcirculation during liver allograft rejection in the rat. Transplantation 1995;59:1241-1248.
    • (1995) Transplantation , vol.59 , pp. 1241-1248
    • Kawano, K.1    Bowers, J.L.2    Kruskal, J.B.3    Clouse, M.E.4
  • 7
    • 0029774106 scopus 로고    scopus 로고
    • Dynamics of arterial and portal venous flow interactions in perfused rat liver: An intravital microscopic study
    • Sherman IA, Dlugosz JA, Barker F, Sadeghi FM, Pang KS: Dynamics of arterial and portal venous flow interactions in perfused rat liver: An intravital microscopic study. Am J Physiol 1996;271:G201-G210.
    • (1996) Am J Physiol , vol.271
    • Sherman, I.A.1    Dlugosz, J.A.2    Barker, F.3    Sadeghi, F.M.4    Pang, K.S.5
  • 8
    • 0021845701 scopus 로고
    • Localization of increased hepatic vascular resistance in liver cirrhosis
    • Shibayama Y, Nakata K: Localization of increased hepatic vascular resistance in liver cirrhosis. Hepatology 1985;5:643-648.
    • (1985) Hepatology , vol.5 , pp. 643-648
    • Shibayama, Y.1    Nakata, K.2
  • 9
    • 0028198897 scopus 로고
    • Endothelin-1 induces direct constriction of hepatic sinusoids
    • Zhang JX, Pegoli W Jr, Clemens MG: Endothelin-1 induces direct constriction of hepatic sinusoids. Am J Physiol 1994;266:G624-G632.
    • (1994) Am J Physiol , vol.266
    • Zhang, J.X.1    Pegoli Jr., W.2    Clemens, M.G.3
  • 10
    • 0028878915 scopus 로고
    • Vessel- and target cell-specific actions of endothelin-1 and endothelin-3 in rat liver
    • Zhang JX, Bauer M, Clemens MG: Vessel- and target cell-specific actions of endothelin-1 and endothelin-3 in rat liver. Am J Physiol 1995; 269:G269-G277.
    • (1995) Am J Physiol , vol.269
    • Zhang, J.X.1    Bauer, M.2    Clemens, M.G.3
  • 11
    • 0023145205 scopus 로고
    • Effect of hepatic nerves, norepinephrine, angiotensin, and elevated central venous pressure on post-sinusoidal resistance sites and intrahepatic pressures in cats
    • Lautt WW, Greenway CV, Legare DJ: Effect of hepatic nerves, norepinephrine, angiotensin, and elevated central venous pressure on post-sinusoidal resistance sites and intrahepatic pressures in cats. Microvas Res 1987;33:50-61.
    • (1987) Microvas Res , vol.33 , pp. 50-61
    • Lautt, W.W.1    Greenway, C.V.2    Legare, D.J.3
  • 13
    • 0014802788 scopus 로고
    • Effects of hepatic venous pressure on transsinusoidal fluid transfer in the liver of the anesthetized cat
    • Greenway CV, Lautt WW: Effects of hepatic venous pressure on transsinusoidal fluid transfer in the liver of the anesthetized cat. Circ Res 1970;26:697-703.
    • (1970) Circ Res , vol.26 , pp. 697-703
    • Greenway, C.V.1    Lautt, W.W.2
  • 14
    • 0023192880 scopus 로고
    • Hepatic venous resistance site in the dog: Localization and validation of intrahepatic pressure measurements
    • Legare DJ, Lautt WW: Hepatic venous resistance site in the dog: Localization and validation of intrahepatic pressure measurements. Can J Physiol Pharmacol 1987;65:352-359.
    • (1987) Can J Physiol Pharmacol , vol.65 , pp. 352-359
    • Legare, D.J.1    Lautt, W.W.2
  • 15
    • 0028052485 scopus 로고
    • ET-1-induced alterations of hepatic microcirculation: Sinusoidal and extrasinusoidal sites of action
    • Bauer M, Zhang JX, Bauer I. Clemens MG: ET-1-induced alterations of hepatic microcirculation: Sinusoidal and extrasinusoidal sites of action. Am J Physiol 1994;267:G143-G149.
    • (1994) Am J Physiol , vol.267
    • Bauer, M.1    Zhang, J.X.2    Bauer, I.3    Clemens, M.G.4
  • 19
    • 0026341256 scopus 로고
    • Characterization of fat-storing cell lines derived from normal and CC14-cirrhotic livers. Differences in the production of interleukin-6
    • Greenwel P, Schwartz M, Rosas M, Peyrol S, Grimaud JA, Rojkind M: Characterization of fat-storing cell lines derived from normal and CC14-cirrhotic livers. Differences in the production of interleukin-6. Lab Invest 1991;65: 644-653.
    • (1991) Lab Invest , vol.65 , pp. 644-653
    • Greenwel, P.1    Schwartz, M.2    Rosas, M.3    Peyrol, S.4    Grimaud, J.A.5    Rojkind, M.6
  • 20
    • 0021808620 scopus 로고
    • The hepatic extracellular matrix. II. Electron immunohistochemical studies in rats with CC14-induced cirrhosis
    • Martinez-Hernandez A: The hepatic extracellular matrix. II. Electron immunohistochemical studies in rats with CC14-induced cirrhosis. Lab Invest 1985;53:166-186.
    • (1985) Lab Invest , vol.53 , pp. 166-186
    • Martinez-Hernandez, A.1
  • 21
    • 0027227345 scopus 로고
    • The hepatic extracellular matrix. I. Components and distribution in normal liver
    • Martinez-Hernandez A, Amenta PS: The hepatic extracellular matrix. I. Components and distribution in normal liver (editorial). Virchows Arch A 1993;423:1-11.
    • (1993) Virchows Arch A , vol.423 , pp. 1-11
    • Martinez-Hernandez, A.1    Amenta, P.S.2
  • 22
    • 0026846805 scopus 로고
    • Rat hepaptic lipocytes express smooth muscle actin upon activation in vivo and in culture
    • Rockey DC, Boyles JK, Gabbiani G, Friedman SL: Rat hepaptic lipocytes express smooth muscle actin upon activation in vivo and in culture. J Submicrosc Cytol Pathol 1992;24:193-203.
    • (1992) J Submicrosc Cytol Pathol , vol.24 , pp. 193-203
    • Rockey, D.C.1    Boyles, J.K.2    Gabbiani, G.3    Friedman, S.L.4
  • 23
    • 0029891589 scopus 로고    scopus 로고
    • Endothelin-induced contractility of stellate cells from normal and cirrhotic rat liver: Implications for regulation of portal pressure and resistance
    • Rockey DC, Weisiger RA: Endothelin-induced contractility of stellate cells from normal and cirrhotic rat liver: Implications for regulation of portal pressure and resistance. Hepatology 1996;24:233-240.
    • (1996) Hepatology , vol.24 , pp. 233-240
    • Rockey, D.C.1    Weisiger, R.A.2
  • 24
    • 0026775513 scopus 로고
    • Fat-storing cells as liver-specific pericytes. Spatial dynamics of agonist-stimulated intracellular calcium transients
    • Pinzani M, Failli P, Ruocco C, Casini A, Milani S, Baldi E, Giotti A, Gentilini P: Fat-storing cells as liver-specific pericytes. Spatial dynamics of agonist-stimulated intracellular calcium transients. J Clin Invest 1992;90:642-646.
    • (1992) J Clin Invest , vol.90 , pp. 642-646
    • Pinzani, M.1    Failli, P.2    Ruocco, C.3    Casini, A.4    Milani, S.5    Baldi, E.6    Giotti, A.7    Gentilini, P.8
  • 25
    • 0030271238 scopus 로고    scopus 로고
    • Gaseous monoxides: A new class of microvascular regulator in the liver
    • Suematsu M, Wakabayashi Y, Ishimura Y: Gaseous monoxides: A new class of microvascular regulator in the liver. Cardiovas Res 1996;32:679-686.
    • (1996) Cardiovas Res , vol.32 , pp. 679-686
    • Suematsu, M.1    Wakabayashi, Y.2    Ishimura, Y.3
  • 26
    • 0030989910 scopus 로고    scopus 로고
    • Molecular mechanisms of hepatic fibrosis and principles of therapy
    • Friedman SL: Molecular mechanisms of hepatic fibrosis and principles of therapy. J Gastroenterol 1997;32:424-430.
    • (1997) J Gastroenterol , vol.32 , pp. 424-430
    • Friedman, S.L.1
  • 27
  • 29
    • 0010412433 scopus 로고
    • Laser Doppler measurements of blood flow within the intestinal wall and on the surface of the liver
    • Koo A, Lam SK, Smaje LH (eds): Singapore, World Scientific Publishing
    • Shepherd AP, Reidel GL, Ward WF: Laser Doppler measurements of blood flow within the intestinal wall and on the surface of the liver; in Koo A, Lam SK, Smaje LH (eds): Microcirculation in the Alimentary Tract. Singapore, World Scientific Publishing, 1983, pp 115-129.
    • (1983) Microcirculation in the Alimentary Tract , pp. 115-129
    • Shepherd, A.P.1    Reidel, G.L.2    Ward, W.F.3
  • 30
    • 0026513626 scopus 로고
    • Measurement of hepatic perfusion in rats by laser Doppler flowmetry
    • Almond NE, Wheatley AM: Measurement of hepatic perfusion in rats by laser Doppler flowmetry. Am J Physiol 1992;262:G203-G209.
    • (1992) Am J Physiol , vol.262
    • Almond, N.E.1    Wheatley, A.M.2
  • 31
    • 0027325378 scopus 로고
    • Interpretation of the laser Doppler flow signal from the liver of the rat
    • Wheatley AM, Almond NE, Stuart ET, Zhao D: Interpretation of the laser Doppler flow signal from the liver of the rat. Microvas Res 1993;45:290-301.
    • (1993) Microvas Res , vol.45 , pp. 290-301
    • Wheatley, A.M.1    Almond, N.E.2    Stuart, E.T.3    Zhao, D.4
  • 32
    • 0027743469 scopus 로고
    • Intraoperative assessment by laser Doppler flowmetry of hepatic perfusion during orthotopic liver transplantation in the rat
    • Wheatley AM, Zhao D: Intraoperative assessment by laser Doppler flowmetry of hepatic perfusion during orthotopic liver transplantation in the rat. Transplantation 1993:56:1315-1318.
    • (1993) Transplantation , vol.56 , pp. 1315-1318
    • Wheatley, A.M.1    Zhao, D.2
  • 33
    • 0025348155 scopus 로고
    • Hepatic microvascular changes associated with development of liver fibrosis and cirrhosis
    • Sherman IA, Pappas SC, Fisher MM: Hepatic microvascular changes associated with development of liver fibrosis and cirrhosis. Am J Physiol 1990;258:H460-H465.
    • (1990) Am J Physiol , vol.258
    • Sherman, I.A.1    Pappas, S.C.2    Fisher, M.M.3
  • 35
    • 3543029597 scopus 로고    scopus 로고
    • Involvement of endothelin in changes to the hepatic microcirculation in the regenerating rat liver
    • Zhang XY, Kuznetsova LV, Richter S, Wheatley AM: Involvement of endothelin in changes to the hepatic microcirculation in the regenerating rat liver. Hepatology 1997;26:276A.
    • (1997) Hepatology , vol.26
    • Zhang, X.Y.1    Kuznetsova, L.V.2    Richter, S.3    Wheatley, A.M.4
  • 36
    • 0030786198 scopus 로고    scopus 로고
    • Cell-specific regulation of expression of plasma-type platelet-activating factor acetylhydrolase in the liver
    • Howard KM, Miller JE, Miwa M, Olson MS: Cell-specific regulation of expression of plasma-type platelet-activating factor acetylhydrolase in the liver. J Biol Chem 1997;272:27543-27548.
    • (1997) J Biol Chem , vol.272 , pp. 27543-27548
    • Howard, K.M.1    Miller, J.E.2    Miwa, M.3    Olson, M.S.4
  • 37
    • 0021147968 scopus 로고
    • Possible involvement of cyclooxygenase products in the actions of platelet-activating factor and of lipoxygenase products in the vascular effects of epinephrme in perfused rat liver
    • Mendlovic F, Corvera S, Garcia-Sainz JA: Possible involvement of cyclooxygenase products in the actions of platelet-activating factor and of lipoxygenase products in the vascular effects of epinephrme in perfused rat liver. Biochem Biophys Res Commun 1984;123:507-514.
    • (1984) Biochem Biophys Res Commun , vol.123 , pp. 507-514
    • Mendlovic, F.1    Corvera, S.2    Garcia-Sainz, J.A.3
  • 38
    • 0010592673 scopus 로고
    • Hepatic resistance in isolated perfused normal and cirrhotic liver
    • Ballet F, Thurman RG (eds): Paris INSERM/Libbey
    • Ballet F: Hepatic resistance in isolated perfused normal and cirrhotic liver; in Ballet F, Thurman RG (eds): Research in Perfused Liver. Paris INSERM/Libbey, 1991, pp 339-360.
    • (1991) Research in Perfused Liver , pp. 339-360
    • Ballet, F.1
  • 39
    • 0027731430 scopus 로고
    • Effect of orthotopic transplantation and chemical denervation of the liver on hepatic hemodynamics in the rat
    • Wheatley AM, Stuart ET, Zhao D, Zimmermann A, Gassel HJ, Blumgart LH: Effect of orthotopic transplantation and chemical denervation of the liver on hepatic hemodynamics in the rat. J Hepatol 1993;19:442-450.
    • (1993) J Hepatol , vol.19 , pp. 442-450
    • Wheatley, A.M.1    Stuart, E.T.2    Zhao, D.3    Zimmermann, A.4    Gassel, H.J.5    Blumgart, L.H.6
  • 40
    • 0027452578 scopus 로고
    • Selective sympathectomy of the liver: A comparison of orthotopic liver transplantation and intraportal 6-hydroxydopamine injection
    • Wheatley AM, Shaw SG, Stuart ET, Zhao D, Gassel HJ, Blumgart LH: Selective sympathectomy of the liver: A comparison of orthotopic liver transplantation and intraportal 6-hydroxydopamine injection. J Auton Pharmacol 1993;13:15-22.
    • (1993) J Auton Pharmacol , vol.13 , pp. 15-22
    • Wheatley, A.M.1    Shaw, S.G.2    Stuart, E.T.3    Zhao, D.4    Gassel, H.J.5    Blumgart, L.H.6
  • 43
    • 0027328719 scopus 로고
    • Endothelin-1 induces cholestasis which is mediated by an increase in portal pressure
    • Isales CM, Nathanson MH, Bruck R: Endothelin-1 induces cholestasis which is mediated by an increase in portal pressure. Biochem Biophys Res Commun 1993;191:1244-1251.
    • (1993) Biochem Biophys Res Commun , vol.191 , pp. 1244-1251
    • Isales, C.M.1    Nathanson, M.H.2    Bruck, R.3
  • 44
    • 0028215277 scopus 로고
    • Endothelin-1 stimulates bile acid secretion and vesicular transport in the isolated perfused rat liver
    • Tanaka A, Katagiri K, Hoshino M, Hayakawa T, Tsukada K, Takeuchi T: Endothelin-1 stimulates bile acid secretion and vesicular transport in the isolated perfused rat liver. Am J Phvsiol 1994;266:G324-G329.
    • (1994) Am J Phvsiol , vol.266
    • Tanaka, A.1    Katagiri, K.2    Hoshino, M.3    Hayakawa, T.4    Tsukada, K.5    Takeuchi, T.6
  • 45
    • 0027537626 scopus 로고
    • Regulation of endothelin-1 action on the perfused rat liver
    • Tran-Thi TA, Kawada N, Decker K: Regulation of endothelin-1 action on the perfused rat liver. FEBS Lett 1993;318:353-357.
    • (1993) FEBS Lett , vol.318 , pp. 353-357
    • Tran-Thi, T.A.1    Kawada, N.2    Decker, K.3
  • 46
    • 0027682715 scopus 로고
    • Endothelins 1 and 3: Potent cholestatic agents secreted and excreted by the liver that interact with cyclosporine
    • Bluhm RE, Frazer MG, Vore M, Pinson CW, Badr KF: Endothelins 1 and 3: Potent cholestatic agents secreted and excreted by the liver that interact with cyclosporine. Hepatology 1993;18:961-968.
    • (1993) Hepatology , vol.18 , pp. 961-968
    • Bluhm, R.E.1    Frazer, M.G.2    Vore, M.3    Pinson, C.W.4    Badr, K.F.5
  • 47
    • 0000154093 scopus 로고
    • The relation of the regenerated liver nodule to the vascular bed in cirrhosis
    • Kelty RH, Baggenstoss AH, Butt HR: The relation of the regenerated liver nodule to the vascular bed in cirrhosis. Gastroenterology 1950; 15:285-295.
    • (1950) Gastroenterology , vol.15 , pp. 285-295
    • Kelty, R.H.1    Baggenstoss, A.H.2    Butt, H.R.3
  • 48
    • 0022383994 scopus 로고
    • Hepatic microcirculation in the perfused cirrhotic rat liver
    • Varin F, Huet M: Hepatic microcirculation in the perfused cirrhotic rat liver. J Clin Invest 1985;76:1904-1912.
    • (1985) J Clin Invest , vol.76 , pp. 1904-1912
    • Varin, F.1    Huet, M.2
  • 49
    • 0021816284 scopus 로고
    • Reduction of the increased portal vascular resistance of the isolated perfused cirrhotic rat liver by vasodilators
    • Bhathal PS, Grossman HJ: Reduction of the increased portal vascular resistance of the isolated perfused cirrhotic rat liver by vasodilators. J Hepatol 1985;1:325-337.
    • (1985) J Hepatol , vol.1 , pp. 325-337
    • Bhathal, P.S.1    Grossman, H.J.2
  • 50
    • 0022496717 scopus 로고
    • Verapamil favorably influences hepatic microvascular exchange and function in rats with cirrhosis of the liver
    • Reichen J, Le M: Verapamil favorably influences hepatic microvascular exchange and function in rats with cirrhosis of the liver. J Clin Invest 1986;78:448-455.
    • (1986) J Clin Invest , vol.78 , pp. 448-455
    • Reichen, J.1    Le, M.2
  • 52
    • 0028957207 scopus 로고
    • Inducible nitric oxide synthase in rat hepatic lipocytes and the effect of nitric oxide on lipocyte contractility
    • Rockey DC, Chung JJ: Inducible nitric oxide synthase in rat hepatic lipocytes and the effect of nitric oxide on lipocyte contractility. J Clin Invest 1995;95:1199-1206.
    • (1995) J Clin Invest , vol.95 , pp. 1199-1206
    • Rockey, D.C.1    Chung, J.J.2
  • 53
    • 33746521801 scopus 로고
    • The cellular basis of hepatic fibrosis. Mechanisms and treatment strategies
    • Friedman SL: The cellular basis of hepatic fibrosis. Mechanisms and treatment strategies. N Engl J Med 1993;119:1828-1835.
    • (1993) N Engl J Med , vol.119 , pp. 1828-1835
    • Friedman, S.L.1
  • 54
    • 0028221993 scopus 로고
    • Endathelins. Biochemistry and pathophysiologic actions
    • Gandhi CR, Berkowitz DE, Watkins WD: Endathelins. Biochemistry and pathophysiologic actions. Anesthesiology 1994;80:892-905.
    • (1994) Anesthesiology , vol.80 , pp. 892-905
    • Gandhi, C.R.1    Berkowitz, D.E.2    Watkins, W.D.3
  • 55
    • 0031916189 scopus 로고    scopus 로고
    • Cellular localization ol endothelin-1 and increased production in liver injury in the rat - Potential for auto-crine and paracrine effects on stellate cells
    • Rockey DC, Fouassier L, Chung JJ, Carayon A, Vallee P, Rev C, Housset C: Cellular localization ol endothelin-1 and increased production in liver injury in the rat - Potential for auto-crine and paracrine effects on stellate cells. Hepatology 1998;27:472-490.
    • (1998) Hepatology , vol.27 , pp. 472-490
    • Rockey, D.C.1    Fouassier, L.2    Chung, J.J.3    Carayon, A.4    Vallee, P.5    Rev, C.6    Housset, C.7
  • 57
    • 0027496798 scopus 로고
    • Endothelin receptors in rat liver: Lipocytes as a contractile target for endothelin 1
    • Housset C, Rockey DC, Bissell DM: Endothelin receptors in rat liver: Lipocytes as a contractile target for endothelin 1. Proc Natl Acad Sci USA 1993;90:9266-9270.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 9266-9270
    • Housset, C.1    Rockey, D.C.2    Bissell, D.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.