Amplification of the c-met, c-erbB-2 and epidermal growth factor receptor gene in human gastric cancers: Correlation to clinical features

Oncology

Volumn 55, Issue 5, 1998, Pages 475-481

  Tsugawa, Kouichiro ^a   Yonemura, Yutaka ^a   Hirono, Yasuo ^a   Fushida, Sachio ^a   Kaji, Masahide ^a   Miwa, Kouichi ^a   Miyazaki, Itsuo ^a   Yamamoto, Hiroshi ^a  

^a KANAZAWA UNIV SCHOOL OF MEDICINE   (Japan)

Author keywords

c erbB 2; c met; Epidermal growth factor receptor; Gastric cancer; Oncogene amplification

Indexed keywords

DNA; EPIDERMAL GROWTH FACTOR RECEPTOR;

ARTICLE; CELL ONCOGENE; CLINICAL FEATURE; CORRELATION FUNCTION; GENE AMPLIFICATION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOBLOTTING; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; ONCOGENE NEU; PERITONEUM METASTASIS; PRIORITY JOURNAL; RECEPTOR GENE; STOMACH CANCER;

EID: 0031858312     PISSN: 00302414     EISSN: None     Source Type: Journal    
DOI: 10.1159/000011898     Document Type: Article

References (28)

1. Tsugawa K, Fushida S, Yonemura Y: Amplification of c-erbB-2 gene in gastric carcinoma: Correlation with survival. Oncology 1993;50: 418-425.
2. Hirono Y, Tsugawa K, Fushida S, Ninomiya I, Yonemura Y, Miyazaki I, Endou Y, Tanaka M, Sasaki T: Amplification of epidermal growth factor receptor gene and its relationship to survival in human gastric cancer. Oncology 1995; 52:182-188.
3. Kuniyasu H, Yasui W, Kitadai Y, Yokozaki H, Ito H, Tahara E: Frequent amplification of the c-met gene in scirrhous type of stomach cancer. Biochem Biophys Res Commun 1992;189: 227-232.
4. Naldini L, Weidner KM, Vigna E, Gaudino G, Bardelli A, Ponzetto C, Narsimhan RP, Hartmann G, Zarnegar R, Michalopoulos GK, Comoglio PM: Scatter factor and hepatocyte growth factor are indistinguishable ligands for the MET receptor. EMBO J 1991;10:2867-2878.
5. Nakamura T, Nishizawa T, Hagiya M, Seki T, Shimonishi M, Sugimura A, Tashiro K, Shimizu S: Molecular cloning and expression of human hepatocyte growth factor. Nature 1989; 342:440-443.
6. Stoker M, Gherardi E, Ferryman M, Gray J: Scatter factor is a fibroblast-derived modulator of epithelial cell mobility. Nature 1987;327: 239-242.
7. Weidner KM, Behrens J, Vandekerckhove J, Birchmeier W: Scatter factor: Molecular characteristics and effect on the invasiveness of epithelial cells. J Cell Biol 1990;111:2097-2108.
8. Carpenter G, Cohen S: Epidermal growth factor. J Biol Chem 1990;265:7709-7712.
9. Japanese Research Society for Gastric Cancer: The general rules for the gastric cancer study in surgery and pathology. Jpn J Surg 1981;11: 127-139.
10. Ullrich A, Coussens L, Hayflick JS, Dull TJ, Gray A, Tam AW, Lee J, Yarden Y, Libermann TA, Schlessinger J, Downward J, Mayes ELV, Whittle N, Waterfield MD, Seeburg PH: Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells. Nature 1984;309:418-425.
11. Fukushige S, Matsubara K, Yoshida M, Sasaki M, Suzuki T, Semba K, Toyoshima K, Yamamoto T: Localization of a novel v-erbB-related gene, c-erbB-2, on human chromosome 17 and its amplification in a gastric cancer cell line. Mol Cell Biol 1986;6:955-958.
12. Dubeau L, Chandler LA, Gralow JR, Nichols PW, Jones PA: Southern blot analysis of DNA extracted from formalin-fixed pathology specimens. Cancer Res 1986;46:2964-2969.
13. Goelz SE, Hamilton SR, Vogelstein B: Purification of DNA from formaldehyde fixed and paraffin embedded human tissue. Biochem Biophys Res Commun 1985;130:118-126.
14. Park M, Dean M, Cooper CS, Schmidt M, O'Brian SJ, Blair DG, Vande Woude GF: Mechanism of met oncogene activation. Cell 1986;45:895-904.
15. Semba K, Kamata N, Toyoshima K, Yamamoto T: A v-erbB-related protooncogene, c-erbB-2, is distinct from the c-erbB-1/epidermal growth factor-receptor gene and is amplified in a human salivary gland adenocarcinoma. Proc Natl Acad Sci USA 1985;82:6497-6501.
16. Xu YH, Ishii S, Clark AJ, Sullivan M, Wilson RK, Ma DP, Roe BA, Merlino GT, Pastan I: Human epidermal growth factor receptor cDNA is homologous to a variety of RNAs overproduced in A431 carcinoma cells. Nature 1984;309:806-810.
17. Kuniyasu H, Yasui W, Yokozaki H, Kitadai Y, Tahara E: Aberrant expression of c-met mRNA in human gastric carcinomas. Int J Cancer 1993;55:72-75.
18. Park M, Dean M, Kaul K, Braun MJ, Gonda MA, Vande Woude G: Sequence of MET protooncogene cDNA has features characteristic of the tyrosine kinase family of growth-factor receptors. Proc Natl Acad Sci USA 1987;84: 6379-6383.
19. Kaji M, Yonemura Y, Harada S, Xjauxu L, Terada I, Yamamoto H: Participation of c-met in the progression of human gastric cancers; anti-c-met oligonucleotides inhibit proliferation or invasiveness of gastric cancer cells. Cancer Gene Ther 1996;3:393-404.
20. Slamon DJ, Clark GM, Wong SG, Levin WJ, Ullrich A, McGuire WL: Human breast cancer: Correlation of relapse and survival with amplification of the HER-2/neu oncogene. Science 1987;235:177-182.
21. Yonemura Y, Ninomiya I, Ohoyama S, Fushida S, Kimura H, Tsugawa K, Kamata T, Yamaguchi A, Miyazaki I, Endou Y, Tanaka M, Sasaki T: Correlation of c-erbB-2 protein expression and lymph node status in early gastric cancer. Oncology 1992;49:363-367.
22. Yoshida K, Tusda T, Matsumura T, Tsujino T, Hattori T, Ito H, Tahara E: Amplification of epidermal growth factor receptor (EGFR) gene and oncogenes in human gastric carcinomas. Virchows Arch B Cell Pathol 1989;57:285-290.
23. Lemoine NR, Jain S, Silvestre F, Lopes C, Hughes CM, McLelland E, Gullick WJ, Filipe MI: Amplification and overexpression of the EGF receptor and c-erbB-2 proto-oncogenes in human stomach cancer. Br J Cancer 1991;64: 79-83.
24. Ishitoya J, Toriyama M, Oguchi N, Kitamura K, Ohshima M, Asano K, Yamamoto T: Gene amplification and overexpression of EGF receptor in squamous cell carcinomas of the head and neck. Br J Cancer 1989;59:559-562.
25. Furuta Y, Takasu T, Asai T, Yoshimura S, Tokuchi F, Shinohara T, Nagashima K, Inuyama Y: Clinical significance of the epidermal growth factor receptor gene in squamous cell carcinomas of the nasal cavities and paranasal sinuses. Cancer 1992;69:358-362.
26. Clinical protocols list. Cancer Gene Ther 1995; 2:137-145.
27. Chen J, Gamou S, Takayanagi A, Shimizu N: A novel gene delivery system using EGF receptor-mediated endocytosis. FEBS Lett 1994; 338:167-169.
28. Harris JD, Gutierrez AA, Hurst HC, Sikora K, Lemoine NR: Gene therapy for cancer using tumor-specific prodrug activation. Gene Ther 1994;1:170-175.