Enhancement of oral absorption in selective 5-HT(1D) receptor agonists: Fluorinated 3-[3-(Piperidin-1-yl)propyl]indoles [2]

Journal of Medicinal Chemistry

Volumn 41, Issue 15, 1998, Pages 2667-2670

  Castro, J L ^a   Collins, I ^a   Russell, M G N ^a   Watt, A P ^a   Sohal, B ^a   Rathbone, D ^a   Beer, M S ^a   Stanton, J A ^a  

^a NEUROSCIENCE RESEARCH CENTRE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ELETRIPTAN; FLUORINE; NARATRIPTAN; PIPERIDINE DERIVATIVE; RIZATRIPTAN; SEROTONIN 1 AGONIST; SEROTONIN 1B AGONIST; SEROTONIN 1D RECEPTOR; SUMATRIPTAN; ZOLMITRIPTAN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTINOCICEPTION; CELL STRAIN CACO 2; CHO CELL; CONTROLLED STUDY; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG METABOLISM; DRUG RECEPTOR BINDING; DRUG SELECTIVITY; FLUORINATION; HEADACHE; HUMAN; HUMAN TISSUE; LETTER; LIVER MICROSOME; LIVER SLICE; MIGRAINE; NONHUMAN; ORAL DRUG ADMINISTRATION; PKA; RAT; RECEPTOR AFFINITY; SUBCUTANEOUS DRUG ADMINISTRATION;

EID: 0031857819     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm980204e     Document Type: Letter

References (20)