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1
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0030954732
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A short-term study of chimeric monoclonal antibody cA2 to tumor necrosis factor *alpha* for Crohn's disease
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Targan SR, Hanauer SB, van Deventer SJH, Mayer L, Present DH, •• Braakman T, DeWoody KL, Schaible TF, Rutgeerts PJ: A short-term study of chimeric monoclonal antibody cA2 to tumor necrosis factor *alpha* for Crohn's disease, N Engl J Med 1997, 337:1029-1035. The largest study until now demonstrating significant effect of a single infusion of an anti-tumor necrosis factor monoclonal antibody in patients with moderate-to-severe treatment-resistant Crohn's disease.
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(1997)
N Engl J Med
, vol.337
, pp. 1029-1035
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Targan, S.R.1
Hanauer, S.B.2
Van Deventer, S.J.H.3
Mayer, L.4
Present, D.H.5
Braakman, T.6
DeWoody, K.L.7
Schaible, T.F.8
Rutgeerts, P.J.9
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2
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0030300013
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Phospholipase A2 activating protein and idiopathic inflammatory bowel disease
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Peterson JW, Dickey DW, Saini SS, Gourley W, Klimpel GR, Chopra AK: Phospholipase A2 activating protein and idiopathic inflammatory bowel disease. Gut 1996, 39:698-704.
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(1996)
Gut
, vol.39
, pp. 698-704
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Peterson, J.W.1
Dickey, D.W.2
Saini, S.S.3
Gourley, W.4
Klimpel, G.R.5
Chopra, A.K.6
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3
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0031043010
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A trial of zileuton versus mesalazine or placebo in the maintenance of remission of ulcerative colitis
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Hawkey CJ, Dube LM, Rountree LV, Linnen PJ, Lancaster JF, and the European Zileuton Study Group for Ulcerative Colitis: A trial of zileuton versus mesalazine or placebo in the maintenance of remission of ulcerative colitis. Gastroenterology 1997, 112:718-724.
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(1997)
Gastroenterology
, vol.112
, pp. 718-724
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Hawkey, C.J.1
Dube, L.M.2
Rountree, L.V.3
Linnen, P.J.4
Lancaster, J.F.5
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4
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0031047277
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Leukotrienes in ulcerative colitis: Results of a multicenter trial of a leukotriene biosynthesis inhibitor, MK-591
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Roberts WG, Simon TJ, Berlin RG, Haggit RC, Snyder ES, Stenson WF, Hanauer SB, Reagan JE, Cagliola A, Tanaka WK, et al.: Leukotrienes in ulcerative colitis: results of a multicenter trial of a leukotriene biosynthesis inhibitor, MK-591. Gastroenterology 1997, 112:725-732.
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(1997)
Gastroenterology
, vol.112
, pp. 725-732
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Roberts, W.G.1
Simon, T.J.2
Berlin, R.G.3
Haggit, R.C.4
Snyder, E.S.5
Stenson, W.F.6
Hanauer, S.B.7
Reagan, J.E.8
Cagliola, A.9
Tanaka, W.K.10
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5
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0030300065
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Alteration of prostaglandin E2 and leukotriene B4 synthesis in chronic inflammatory bowel disease
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Schmidt C, Baumeister B, Kipnowski J, Schiermeyer-Dunkhase B, Vetter H: Alteration of prostaglandin E2 and leukotriene B4 synthesis in chronic inflammatory bowel disease. Hepatogastroenterology 1996, 43:1508-1512.
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(1996)
Hepatogastroenterology
, vol.43
, pp. 1508-1512
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Schmidt, C.1
Baumeister, B.2
Kipnowski, J.3
Schiermeyer-Dunkhase, B.4
Vetter, H.5
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6
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0030879843
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Effects of a thromboxane A2 receptor antagonist in an animal model of inflammatory bowel disease
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Taniguchi T, Tsukada H, Nakamura H, Kodama M, Fukuda K, Tominaga M, • Seino Y: Effects of a thromboxane A2 receptor antagonist in an animal model of inflammatory bowel disease. Digestion 1997, 58:476-478. Simple, well-conducted methodologically, and suggests that thromboxane blockade may have a role in the treatment of IBD.
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(1997)
Digestion
, vol.58
, pp. 476-478
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Taniguchi, T.1
Tsukada, H.2
Nakamura, H.3
Kodama, M.4
Fukuda, K.5
Tominaga, M.6
Seino, Y.7
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7
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0029885179
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Picotamide inhibition of excess in vitro thromboxane B2 release by colorectal mucosa in inflammatory bowel disease
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Collins CE, Benson MJ, Burnham WR, Ramptom DS: Picotamide inhibition of excess in vitro thromboxane B2 release by colorectal mucosa in inflammatory bowel disease. Aliment Pharmacol Ther 1996, 10:315-320.
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(1996)
Aliment Pharmacol Ther
, vol.10
, pp. 315-320
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Collins, C.E.1
Benson, M.J.2
Burnham, W.R.3
Ramptom, D.S.4
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8
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0031016144
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An enteral formula containing fish oil, indigestible oligosaccharides, gum arabic and antioxidants affects plasma and colonic phospholipid fatty acid and prostaglandin profiles in pigs
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Campbell JM, Fahey GC, Lichtensteiger CA, Demichele SJ. Garleb KA: An enteral formula containing fish oil, indigestible oligosaccharides, gum arabic and antioxidants affects plasma and colonic phospholipid fatty acid and prostaglandin profiles in pigs. J Nutr 1997, 127:137-145.
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(1997)
J Nutr
, vol.127
, pp. 137-145
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Campbell, J.M.1
Fahey, G.C.2
Lichtensteiger, C.A.3
Demichele, S.J.4
Garleb, K.A.5
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9
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0029830453
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Platelet-activating factor acetylhydrolase activity in intestinal mucosa and plasma of patients with Crohn's disease
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Kald B, Smedh K, Olaison G, Sjodahl R, Tagesson C: Platelet-activating factor acetylhydrolase activity in intestinal mucosa and plasma of patients with Crohn's disease, Digestion 1996, 57:472-477.
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(1996)
Digestion
, vol.57
, pp. 472-477
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Kald, B.1
Smedh, K.2
Olaison, G.3
Sjodahl, R.4
Tagesson, C.5
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10
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0030944609
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Substance P containing nerve fibers in rectal mucosa of ulcerative colitis
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Watanabe T, Kubota Y, Muto T: Substance P containing nerve fibers in • rectal mucosa of ulcerative colitis. Dis Colon Rectum 1997, 40:718-725. An interesting new method for staining and quantitation of substance P-containing nerve fibers in the intestinal mucosa.
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(1997)
Dis Colon Rectum
, vol.40
, pp. 718-725
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Watanabe, T.1
Kubota, Y.2
Muto, T.3
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11
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0029843304
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Abnormal neuropeptide concentration in rectal mucosa of patients with inflammatory bowel disease
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Yamamoto H, Morise K, Kusugami K, Furusawa A, Konagaya T, Nishio Y, Kaneko H, Uchida K, Nagai H, Mrrsuma T, Nagura H: Abnormal neuropeptide concentration in rectal mucosa of patients with inflammatory bowel disease. J Gastroenterol 1996, 31:525-532.
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(1996)
J Gastroenterol
, vol.31
, pp. 525-532
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Yamamoto, H.1
Morise, K.2
Kusugami, K.3
Furusawa, A.4
Konagaya, T.5
Nishio, Y.6
Kaneko, H.7
Uchida, K.8
Nagai, H.9
Mrrsuma, T.10
Nagura, H.11
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12
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8244235129
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Increased nitric oxide production and inducible nitric oxide synthase activity in colonic mucosa of patients with active ulcerative colitis and Crohn's disease
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Kimura H, Miura S, Shigematsu T, Ohkubo N, Tsuzuki Y, Kurose I, Higuchi •• H, Akiba Y, Hokari R, Hirokawa M, et al.: Increased nitric oxide production and inducible nitric oxide synthase activity in colonic mucosa of patients with active ulcerative colitis and Crohn's disease, Dig Dis Sci 1997, 42:1047-1054. A "multilevel" work correlating tissue activities of NOS isoforms. plasma levels of NO metabolites, and clinical and histologic meaning, demonstrating a significant increase of these substances in the inflamed tissues.
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(1997)
Dig Dis Sci
, vol.42
, pp. 1047-1054
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Kimura, H.1
Miura, S.2
Shigematsu, T.3
Ohkubo, N.4
Tsuzuki, Y.5
Kurose, I.6
Higuchi, H.7
Akiba, Y.8
Hokari, R.9
Hirokawa, M.10
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13
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8044257700
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Amelioration of chronic inflammation by ingestion of elemental diet in a rat model of granulomatous enteritis
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Tanaka S, Miura S, Kimura H, Ohkubo N, Tsuzuki Y, Fukumura D, Serizawa H, Kurose I, Mori M, Ishii H: Amelioration of chronic inflammation by ingestion of elemental diet in a rat model of granulomatous enteritis. Dig Dis Sci 1997, 42:408-419.
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(1997)
Dig Dis Sci
, vol.42
, pp. 408-419
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Tanaka, S.1
Miura, S.2
Kimura, H.3
Ohkubo, N.4
Tsuzuki, Y.5
Fukumura, D.6
Serizawa, H.7
Kurose, I.8
Mori, M.9
Ishii, H.10
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14
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0030899297
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The effect of inhibitors of inducible nitric oxide synthase on chronic colitis in the rhesus monkey
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Ribbons KA, Currie MG, Connor JR, Manning PT, Allen PC, Didier P, •• Ratterree MS, Clark DA, Miller MJS: The effect of inhibitors of inducible nitric oxide synthase on chronic colitis in the rhesus monkey. J Pharmacol Exp Ther 1997, 280:1008-1015. In the first work of its kind in a primate, this interesting model resembling UC showed failure of iNOS inhibition to improve colitis.
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(1997)
J Pharmacol Exp Ther
, vol.280
, pp. 1008-1015
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Ribbons, K.A.1
Currie, M.G.2
Connor, J.R.3
Manning, P.T.4
Allen, P.C.5
Didier, P.6
Ratterree, M.S.7
Clark, D.A.8
Miller, M.J.S.9
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15
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0031041841
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Inducible nitric oxide synthase plays a critical role in resolving intestinal inflammation
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McCafferty DM, Mudget JS, Swain MG. Kubes P: Inducible nitric oxide synthase plays a critical role in resolving intestinal inflammation. Gastroenterology 1997, 112:1022-1027.
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(1997)
Gastroenterology
, vol.112
, pp. 1022-1027
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McCafferty, D.M.1
Mudget, J.S.2
Swain, M.G.3
Kubes, P.4
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16
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0030981289
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Circulating antioxidant concentrations in children with inflammatory bowel disease
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Hoffenberg EJ, Deutsch J, Smith S, Sokol RJ: Circulating antioxidant • concentrations in children with inflammatory bowel disease. Am J Clin Nutr 1997, 65:1482-1488. Interesting results suggesting that the oxidative burden in children with IBD may cause decrease of circulating antioxidants.
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(1997)
Am J Clin Nutr
, vol.65
, pp. 1482-1488
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Hoffenberg, E.J.1
Deutsch, J.2
Smith, S.3
Sokol, R.J.4
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17
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0030797642
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Circulating antioxidants in ulcerative colitis and their relationship to disease severity and activity
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Ramakrishna BS, Varghese R, Jayakumar S, Mathan M, Balasubramanian KA: Circulating antioxidants in ulcerative colitis and their relationship to disease severity and activity. J Gastroenterol Hepatol 1997, 12:490-494.
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(1997)
J Gastroenterol Hepatol
, vol.12
, pp. 490-494
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Ramakrishna, B.S.1
Varghese, R.2
Jayakumar, S.3
Mathan, M.4
Balasubramanian, K.A.5
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18
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0030747182
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Effect of Z-103 on TNB-induced colitis in rats
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Yoshikawa T, Yamaguchi T, Yoshida N, Yamamoto H, Kitazumi S, • Takahashi S, Naito Y, Kondo M: Effect of Z-103 on TNB-induced colitis in rats. Digestion 1997, 58:464-468. An established model of colitis in which a presumed antioxidant has therapeutic effect similar to that of sulfasalazine.
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(1997)
Digestion
, vol.58
, pp. 464-468
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Yoshikawa, T.1
Yamaguchi, T.2
Yoshida, N.3
Yamamoto, H.4
Kitazumi, S.5
Takahashi, S.6
Naito, Y.7
Kondo, M.8
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19
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0031047320
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Quantification of inflammatory mediators in stool samples of patients with inflammatory bowel disorders and controls
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Bischoff SC, Grabowsky J. Manns MP: Quantification of inflammatory mediators in stool samples of patients with inflammatory bowel disorders and controls, Dig Dis Sci 1997, 24:394-403.
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(1997)
Dig Dis Sci
, vol.24
, pp. 394-403
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Bischoff, S.C.1
Grabowsky, J.2
Manns, M.P.3
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