Differential effect of halothane and forskolin on platelet cytosolic Ca2+ mobilization and aggregation

Anesthesiology

Volumn 89, Issue 2, 1998, Pages 401-410

  Corbin, François ^b   Blaise, Gilbert ^b   Sauvé, Rémy ^a  

^a UNIVERSITÉ DE MONTRÉAL   (Canada)

^b NONE

Author keywords

Bleeding; Phospholipase C; Second messenger; Thrombus; Time

Indexed keywords

15 HYDROXY 11ALPHA,9ALPHA EPOXYMETHANOPROSTA 5,13 DIENOIC ACID; CALCIUM ION; CYCLIC AMP; FORSKOLIN; HALOTHANE; PHOSPHOLIPASE C; THAPSIGARGIN; THROMBIN; THROMBOCYTE ACTIVATING FACTOR;

ARTICLE; CALCIUM CELL LEVEL; CALCIUM MOBILIZATION; DRUG ACTIVITY; DRUG EFFECT; ENZYME ACTIVITY; FLUOROMETRY; HUMAN; HUMAN CELL; PRIORITY JOURNAL; QUANTITATIVE ASSAY; SECOND MESSENGER; SIGNAL TRANSDUCTION; THROMBOCYTE AGGREGATION; THROMBUS;

ANESTHETICS, INHALATION; BLOOD PLATELETS; CALCIUM; FORSKOLIN; HALOTHANE; HUMANS; PHOSPHOLIPASE C; PLATELET AGGREGATION; PLATELET AGGREGATION INHIBITORS; SIGNAL TRANSDUCTION; SPECTROMETRY, FLUORESCENCE;

EID: 0031857330     PISSN: 00033022     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000542-199808000-00017     Document Type: Article

References (28)

1. Gibbs NM: The effect of anaesthetic agents on platelet function. Anesth Intens Care 1991; 19:495-505
2. Dalsgaard-Nielsen J, Risbo A, Simmelkjaer P, Gormsen J: Impaired platelet aggregation and increased bleeding time during general anaesthesia with halothane. Br J Anaesth 1981; 53:1039-42
3. Dalsgaard-Nielsen J, Gormsen J: Effects of halothane on platelet function. Thromb Haemost 1980; 44:143-5
4. Hofmann JG, Siedel U, Till U: Effect of halothane on metabolic ATP and induced aggregation of human blood platelets. Biomed Biochim Acta 1989; 48:337-41
5. Bertha BG, Folts JD, Nugent M, Rusy BF: Halothane, but not isoflurane or enflurane, protects against spontaneous and epinephrine-exacerbated acute thrombus formation in stenosed dog coronary arteries. ANESTHESIOLOGY 1989; 71:96-102
6. Siess W: Molecular mechanisms of platelet activation. Physiol Rev 1989; 69:158-78
7. Rink TJ, Sage SO: Calcium signaling in human platelets. Annu Rev Physiol 1990; 52:431-49
8. Freeman LC, Li Q: Effects of halothane on delayed after depolarization and calcium transients in dog ventricular myocytes exposed to isoproterenol. ANESTHESIOLOGY 1991; 74:146-54
9. 2+ mobilization in endothelial cells by volatile anesthetics. Biochem Pharmacol 1993; 45:1137-42
10. 2+ influx in bovine aortic endothelial cells. ANESTHESIOLOGY 1996; 85:366-79
11. Kohro S, Yamakage M: Direct inhibitory mechanisms of halothane on human platelet aggregation. ANESTHESIOLOGY 1996; 85:96-106
12. Sprague DH, Yang JC, Ngai SH: Effects of isoflurane and halothane on contractility and the cyclic 3′,5′-adenosine monophosphate system in the rat aorta. ANESTHESIOLOGY 1974; 40:162-7
13. Walter F, Vulliemoz Y, Verosky M, Triner L: Effects of halothane on the cyclic 3′,5′-adenosine monophosphate enzyme system in human platelets. Anesth Analg 1980; 59:856-61
14. Haynes DH: Effects of cyclic nucleotides and protein kinases on platelet calcium homeostasis and mobilization. Platelets 1993; 4:231-42
15. 2+ entry regulated by intracellular stores. Biochem J 1990; 265:675-80
16. Franks NP, Lieb WR: Selective actions of volatile general anaesthetics at molecular and cellular levels. Br J Anaesth 1993; 71:65-76
17. Biaise G, To Q, Parent M, Lagarde B, Asenjo F, Sauvé R: Does halothane interfere with the release, action, or stability of endothelium-derived relaxing factor/nitric oxide? ANESTHESIOLOGY 1994; 80:417-26
18. 2+ indicators with greatly improved fluorescence properties. J Biol Chem 1985; 260:3440-50
19. Putney JW: Capacitative calcium entry revisited. Cell Calcium 1990; 11:611-24
20. Thastrup O, Linnebjerg H, Bjerrum PJ, Knudsen JB, Christensen SB: The inflammatory and tumor-promoting sesquiterpene lactone, thapsigargin, activates platelets by selective mobilization of calcium as shown by protein phosphorylations. Biochim Biophys Acta 1987; 927:65-73
21. 2+ signaling in A7r5 cultured vascular smooth muscle cells. Mol Pharmacol 1991; 40:1006-13
22. 2+-ATPase activity by volatile anesthetics. ANESTHESIOLOGY 1993; 79:774-80
23. Suganuma A, Nakasima S, Okano Y, Nozawa Y: Mass contents of inositol 1,4,5-triphosphate and 1,2-diacylglycerol in human platelets stimulated with a thromboxane analogue and thrombin. Thromb Haemost 1992; 68:341-5
24. Sage SO, Rink TJ: The kinetics of changes in intracellular calcium concentration in fura-2 loaded human platelets. J Biol Chem 1987; 262:16364-9
25. 2+ store depletion in human platelets. Cell Calcium 1994; 15:381-90
26. Zucker MB, Troll W, Belman S: The tumor-promotor phorbol ester (12-O-tetradecanoyl-phorbol 13-acetate), a potent aggregating agent for blood platelets. J Cell Biol 1974; 60:325-36
27. Rink TJ, Sanchez A, Hallam TJ: Diacylglycerol and phorbol ester stimulate secretion without raising cytoplasmic free calcium in human platelets. Nature 1983; 305:317-9
28. Rooney TA, Hager R, Stubbs C, Thomas AP: Halothane regulates G-protein-dependent phospholipase C activity in turkey erythrocyte membranes. J Biol Chem 1993; 268:15550-6