Double esterase staining and other neutrophilic granule abnormalities in 237 patients with the myelodysplastic syndrome studied by the Cancer and Leukemia Group B

Acta Haematologica

Volumn 100, Issue 1, 1998, Pages 13-16

  Elghetany, M Tarek ^a,h   Peterson, Bercedis ^b   MacCallum, Jane ^c   Nelson, Douglas A ^c   Varney, Judy F ^c   Sullivan, Arthur K ^g   Silverman, Lewis R ^d   Schiffer, Charles A ^e   Davey, Frederick R ^c   Bloomfield, Clara D ^f  

^a UNIVERSITY OF TEXAS MEDICAL BRANCH   (United States)

^b CALGB Statistical Center   (United States)

^c SUNY UPSTATE MEDICAL UNIVERSITY   (United States)

^d MOUNT SINAI HOSPITAL   (United States)

^e UNIVERSITY OF MARYLAND GREENEBAUM CANCER CENTER   (United States)

^f ROSWELL PARK CANCER INSTITUTE   (United States)

^g MCGILL UNIVERSITY   (Canada)

^h University of Texas Medical Branch School of Medicine   (United States)

Author keywords

Cytochemistry; Esterase; Myelodysplastic syndromes; Neutrophils

Indexed keywords

CD15 ANTIGEN; ELASTASE; ESTERASE; GLYCOPROTEIN; LACTOFERRIN; MEMBRANE PROTEIN; MYELOPEROXIDASE;

ARTICLE; CELL GRANULE; CONTROLLED STUDY; CYTOCHEMISTRY; DISEASE SEVERITY; ENZYME ACTIVITY; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; MAJOR CLINICAL STUDY; MYELODYSPLASTIC SYNDROME; NEUTROPHIL; PRIORITY JOURNAL; REFRACTORY ANEMIA;

BONE MARROW CELLS; CYTOPLASMIC GRANULES; ESTERASES; HUMANS; MYELODYSPLASTIC SYNDROMES; NEUTROPHILS; STAINING AND LABELING;

EID: 0031856750     PISSN: 00015792     EISSN: None     Source Type: Journal    
DOI: 10.1159/000040855     Document Type: Article

References (10)

1. Bendix-Hansen K, Kerndrup G: Myeloperoxidase-deficient polymorphonuclear leukocytes. V. Relationship to FAB-classification and neutrophil alkaline phosphatase activity in primary myelodysplastic syndromes. Scand J Haematol 1985;35:197-200.
2. Seo IS, Li C-Y, Yam LT: Myelodysplastic syndrome: Diagnostic implications of cytochemical and immunocytochemical studies. Mayo Clin Proc 1993;68:47-53.
3. Scott CS, Cahill A, Bynoe AG, Ainley MJ, Hough D, Roberts BE: Esterase cytochemistry in primary myelodysplastic syndromes and megaloblastic anemia: Demonstration of abnormal staining patterns associated with dysmyelopoiesis. Br J Haematol 1983;55:411-418.
4. Hayhoe FGJ, Quaglino D: Haematological Cytochemistry, ed 3. New York, Churchill Livingstone, 1994.
5. Uphoff CC, Gignac SM, Metge K, Zschunke F, Radzun HJ, Drexler HG: Expression of the monocyte-specific esterase gene in leukemia-lymphoma cell lines. Leukemia 1993;7:58-62.
6. Drexler HG, Gignac SM, Patel D, Scott CS: Lineage-specific monocytic esterase, a distinct marker for leukemias of monocytic origin: Cytochemical, isoenzymatic and biochemical features. Leuk Lymphoma 1991;4:295-312.
7. Patel D, Hooper NM, Scott CS: Subcellular fractionation studies indicate an intracellular localization for monocyte specific esterase. Br J Haematol 1993;84:608-614.
8. Elghetany MT, Sullivan AK, Kurec AS, MacCullum JM, Bloomfield CD, Sobol RE, Davey FR: The use of monoclonal antibodies against primary myeloid granules in normal and leukemic cells. Am J Clin Pathol 1992;98:430-436.
9. Yourno J, Walsh J, Kornatowski G, O'Connor D, Kumar SA: Nonspecific esterases of leukemia cell lines: Evidence for activation of myeloid-associated zymogen in HL-60 by phorbol esters. Blood 1984;63:238-241.
10. Markay GM, McCormick JA, Morris TCM, Alexander HD, Nolan L, Morgan LM, Reynolds ME, Edgar S, Bell AL, McCaigue MD, Robertson JH: Monocyte esterase deficiency in malignant neoplasia. J Clin Pathol 1990;45: 282-286.