Dobutamine antagonizes epinephrine's biochemical and cardiotonic effects: Results of an in vitro model using human lymphocytes and a clinical study in patients recovering from cardiac surgery

Anesthesiology

Volumn 89, Issue 1, 1998, Pages 49-57

  Prielipp, Richard C ^a   MacGregor, Drew A ^b   Royster, Roger L ^b   Kon, Neal D ^b   Hines, Michael H ^b   Butterworth IV, John F ^b  

^a WAKE FOREST SCHOOL OF MEDICINE   (United States)

^b NONE

Author keywords

Cyclic adenosine monophosphate; Partial agonist; Pseudoantagonist

Indexed keywords

ADRENALIN; DOBUTAMINE;

ARTICLE; CARDIOVASCULAR RESPONSE; CLINICAL ARTICLE; CLINICAL TRIAL; CORONARY ARTERY BYPASS GRAFT; CYCLIC AMP BLOOD LEVEL; DOSE RESPONSE; DRUG ANTAGONISM; DRUG MECHANISM; HEART INDEX; HUMAN; HUMAN CELL; INOTROPISM; LYMPHOCYTE; PHASE 1 CLINICAL TRIAL; PHASE 2 CLINICAL TRIAL; PRIORITY JOURNAL; TREATMENT OUTCOME;

ADRENERGIC AGONISTS; CARDIOTONIC AGENTS; CELLS, CULTURED; CORONARY ARTERY BYPASS; CYCLIC AMP; DOBUTAMINE; DOSE-RESPONSE RELATIONSHIP, DRUG; EPINEPHRINE; HEART RATE; HEMODYNAMIC PROCESSES; HUMANS; LYMPHOCYTES; POSTOPERATIVE COMPLICATIONS;

EID: 0031855423     PISSN: 00033022     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000542-199807000-00010     Document Type: Article

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