Isocratic HPLC separation of several racemic drugs with two stereogenic centers on a pirkle urea-type chiral stationary phase

Journal of Liquid Chromatography and Related Technologies

Volumn 21, Issue 12, 1998, Pages 1817-1831

  Aboul Enein, Hassan Y ^a   Al Duraibi, Ibrahim A ^a  

^a KING FAISAL SPECIALIST HOSPITAL AND RESEARCH CENTER   (Saudi Arabia)

Author keywords

[No Author keywords available]

Indexed keywords

3,4 DICHLORO N METHYL N [2 (1 PYRROLIDINYL)CYCLOHEXYL]BENZAMIDE; FORMOTEROL; INDENOLOL; LABETALOL; NADOLOL;

ARTICLE; DRUG DETERMINATION; DRUG ISOLATION; ENANTIOMER; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; STEREOISOMERISM;

EID: 0031855407     PISSN: 10826076     EISSN: None     Source Type: Journal    
DOI: 10.1080/10826079808005894     Document Type: Article

References (17)

1. J. Trofast, K. Osterberg, B. Kallstrom, B. Waldeck, Chirality, 3, 443-450 (1991).
2. B. Waldeck, Chirality, 5, 350-355 (1993).
3. B. Testa, W. F. Trager, Chirality, 2, 129-133 (1990).
4. S. Ahuja "The Importance of Chiral Separations in Pharmaceuticals," chapter 10, in The Impact of Stereochemistry in Drug Development and Use, edited by H. Y. Aboul-Enein, I. W. Wainer, John Wiley and Sons, New York, 1997, pp. 287-315.
5. D. R. Abernethy, N. S. Andrawis, "Stereoisomeric Drugs in the Therapeutics, Clinical Perspectives" in Drug Stereochemistry; Analytical Methods and Pharmacology, Irving W. Wainer, ed., Marcel Dekker, Inc., New York, 1993, pp. 385-397.
6. H. Y. Aboul-Enein, V. Serignese, J. Liq. Chromatogr. & Rel. Technol., 19, 933-938 (1996).
7. H. Y. Aboul-Enein, L. I. Abou-Basha, J. Liq. Chromatogr., 19, 383-392 (1996).
8. H. Y. Aboul-Enein, M. R. Islam, J. Chromatogr., 511, 109-114 (1990).
9. N. R. Srinivas, W. C. Shyu, V. R. Shah, D. A. Campbell, R. H. Barbhaiya, Biomed. Chromatogr., 9, 226-228 (1995).
10. F. J. Belas, M. A. Phillips, N. R. Srinivas, R. H. Barbhaiya, I. A. Blair, Biomed. Chromatogr., 9, 140-145 (1995).
11. D. Faulds, L. M. Hollingshead, K. L. Goa, Drugs, 42, 115-137 (1991).
12. C. G. Lofdahl, P. J. Barnes, Acta Pharmacol. Toxicol. Suppl., 58, 91-111 (1986).
13. Annual Drug Data Report Vol. 3, J. R. Prous, ed., J. R. Prous, S.A., Inter national Publishers, Barcelona, Spain, 1981, pp. 1-272.
14. Annual Drug Data Report Vol. 5, J. R. Prous, ed., J. R. Prous, S.A., Inter national Publishers, Barcelona, Spain, 1983, pp. 1-210.
15. Annual Drug Data Report Vol. 2, J. R. Prous, ed., J. R. Prous, S.A., Inter national Publishers, Barcelona, Spain, 1981, pp. 1-252.
16. T. Cleveland, J. Liq. Chromatogr., 18, 649-671 (1995).
17. M. Hoshino, K. Yajima, Y. Suzuki, A. Okahira, J. Chromatogr. B, 661, 281-289 (1994).