Antidepressant-like effects of 5-hydroxytryptamine(1A) receptor agonists on operant responding under a response duration differentiation schedule

Behavioural Pharmacology

Volumn 9, Issue 4, 1998, Pages 309-318

  Kinney, G G ^a,b   Griffith, J C W ^a   Hudzik, T J ^a  

^a Astra Arcus USA   (United States)

^b BRISTOL MYERS SQUIBB   (United States)

Author keywords

5 HT(1A) receptor; Depression; Operant behavior; Rat; Response duration differentiation

Indexed keywords

2 DIPROPYLAMINO 8 HYDROXYTETRALIN; ALPRENOLOL; BUSPIRONE; CHLORPROMAZINE; LYSERGIDE; PHENOTHIAZINE DERIVATIVE; PROPRANOLOL; SEROTONIN 1A AGONIST; TRAZODONE;

ANIMAL MODEL; ARTICLE; BEHAVIOR; CONTROLLED STUDY; DEPRESSION; INSTRUMENTAL CONDITIONING; INTRAPERITONEAL DRUG ADMINISTRATION; MALE; NONHUMAN; RAT; REINFORCEMENT;

EID: 0031852402     PISSN: 09558810     EISSN: None     Source Type: Journal    
DOI: 10.1097/00008877-199807000-00002     Document Type: Article

References (32)

1. Amsterdam JD, Berwish N, Potter L, Rickels K (1987). Open trial of gepirone in the treatment of major depressive disorder. Curr Ther Res 41:185-193.
2. 1A antagonists. Trends Neurosci 19:378-383.
3. 1A receptors in the dorsal raphe and hippocampus: I. Effect of spiperonc. J Pharmacol Exp Ther 265:7-15.
4. 1A receptors induces rapid antidepressant response. Neuropsychopharmacol 16:333-338.
5. DeVry J (1995). 5-HTIA receptor agonists: recent developments and controversial issues. Psychopharmacol 121:1-26.
6. 1A receptors in depression and anxiety Stahl SM, Gastpar M, Keppel Hesselink JM, Traber J (editors). New York: Raven Press. pp. 55-81.
7. Fletcher PJ (1993). A comparison of the effects of dorsal or median raphe injections of 8-OH-DPAT in three operant tasks measuring response inhibition. Behav Brain Res 54:187-197.
8. Fletcher PJ (1994). Effects of 8-OH-DPAT, 5-CT and muscimol on behaviour maintained by a DRL20 schedule of reinforcement, following microinjection into the dorsal or median raphe nuclei. Behav Pharmacol 5:326-336.
9. Fletcher PJ (1995). Effects of combined or separate 5,7-dihydroxytryptamine lesions of the dorsal and median raphe nuclei on responding maintained by a DRL 20s schedule of food reinforcement. Brain Res 675:45-54.
10. 1A receptor antagonist and an SSRI in vivo: effects on 5-HT cell firing and extracellular 5-HT. Br J Pharmacol 115:1064-1070.
11. Goldberg AL, Finnerty RJ (1979). The comparative efficacy of buspirone and diazepan in the treatment of anxiety. Am J Psychiatry 136:1184-1187.
12. Hudzik TJ, McMillan DE (1994a). Drug effects on response-duration differentiation I: differential effects of drugs of abuse. Psychopharmacol 114:620-627.
13. Hudzik TJ, McMillan DE (1994b). Drug effects on response-duration differentiation II: selective effects of antidepressant drugs. J Pharmacol Exp Ther 268:1335-1342.
14. Jacobs BL, Azmitia EC (1992). Structure and function of the brain serotonin system. Physiol Rev 72:165-229.
15. Lucki I, Singh A, Kreiss DS (1994). Antidepressant-like behavioral effects of serotonin recfeptor agonists. Neurosci Biobehav Rev 18:85-95.
16. Martin P, Tissier MH, Adrien J, Puech AJ (1991). Antidepressant-like effects of buspirone mediated by the 5-HT1A post-synaptic receptors in the learned helplessness paradigm. Life Sci 48:2505-2511.
17. McMillan DE, Patton RA (1965). Differentiation of a precise timing response. J Exp Anal Behav 8:219-226.
18. McMillan DE, Adams SL, Wenger GR, McClure GYH, Hardwick WC (1994). Effects of drugs on response duration differentiation III. Acute variation of reinforced duration. Pharmacol Biochem Behav 48:941-957.
19. Molliver ME (1987). Serotonergic neuronal systems: what their anatomic organization tells us about function. J Clin Psychopharmacol 7:3S-23S.
20. O'Donnell JM, Seiden LS (1983). Differential reinforcement of low rate 72-s schedule: selective effects of antidepressant drugs. J Pharmacol Exp Ther 224:80-88.
21. Perez V, Gilaberte I, Faries D, Alvarez E, Artigas F (1997). Randomised, double-blind, placebo-controlled trial of pindolol in combination with fluoxetine antidepressant treatment. Lancet 349:1594-1597.
22. Pollard GT, Howard JL (1986). Similar effects of antidepressant and non-antidepressant drugs on behavior under an interresponse-time > 72-s schedule. Psychopharmacol 89:253-258.
23. Richards JB, Sabol KE, Hand TH, Jolly DC, Marck GJ, Seiden JS (1994). Buspirone, gepirone, ipsapirone, and zalospirone have distinct effects on the differential-reinforcement-oflow-rate 72-s schedule when compared with 5-HTP and diazepam. Psychopharmacol 114:39-46.
24. Schulze GE, Paule MG (1990). Acute effects of d-amphetamine in a monkey operant behavioral test battery. Pharmacol Biochem Behav 35:759-765.
25. Schulze GE, Paule MG (1991). Effects of morphine sulfate on operant behavior in rhesus monkeys. Pharmacol Biochem Behav 38:77-83.
26. Schulze GE, McMillan DE, Bailey JR, Scallet A, Ali SF, Slikker W, Paule MG (1988). Acute effects of delta-9-tetrahydrocannabinol in rhesus monkeys as measured by performance in a battery of complex operant tests. J Pharmacol Exp Ther 245:178-186.
27. Seiden LS (1983). Effects of trazadonc, fluoxetine and bupropion on rats responding under a schedule of differential reinforcement of low rate 72 s (DRL72 s). Fed Proc 42:1163.
28. 1A receptor ligand. Eur J Pharmacol 201:163-169.
29. 1A selective agonists. Eur J Pharmacol 128:295-298.
30. Steinbusch HWM (1981). Distribution of serotonin-immunoreactivity in the central nervous system of the rat - cell bodies and terminals. Neuroscience 6:557-618.
31. Tam EM, Lam RW, Levitt AJ (1995). Treatment of seasonal affective disorder: a review. Can J Psychiatry 40:457-466.
32. Wilkinson LO, Dourish CT (1991). Serotonin and animal behavior. In: Serotonin receptor subtypes: basic and clinical aspects. Peroutka SJ (editor) New York: Wiley-Liss. pp. 147-210.