Superiority of hepatic arterial infusion in preventing catabolism of 5-FU compared with portal vein infusion revealed by an in vivo 19F NMR study

Cancer Chemotherapy and Pharmacology

Volumn 42, Issue 4, 1998, Pages 341-344

  Okuno, Kiyotaka ^a   Hirai, Norihiko ^a   Lee, Yung Sun ^a   Tarabar, Dino ^a   Ueno, Hideo ^b   Yasutomi, Masayuki ^a  

^a KINKI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b KYOWA HAKKO KOGYO CO LTD   (Japan)

Author keywords

5 FU; 19F NMR; FBAL; Hepatic arterial infusion; Portal vein infusion

Indexed keywords

ALPHA FLUORO BETA ALANINE; FLUOROURACIL;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG EFFICACY; DRUG METABOLISM; DRUG MONITORING; HEPATIC ARTERY; INTRAARTERIAL DRUG ADMINISTRATION; INTRAVENOUS DRUG ADMINISTRATION; MALE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PORTAL VEIN; PRIORITY JOURNAL; RAT;

ANIMALS; ANTIMETABOLITES, ANTINEOPLASTIC; BETA-ALANINE; FLUORINE; FLUOROURACIL; HEPATIC ARTERY; INFUSIONS, INTRA-ARTERIAL; INFUSIONS, INTRAVENOUS; ISOTOPES; MAGNETIC RESONANCE SPECTROSCOPY; MALE; PORTAL VEIN; RATS; RATS, WISTAR; TAIL;

EID: 0031851710     PISSN: 03445704     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002800050827     Document Type: Article

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