Disturbed initiation of gastric interdigestive migrating complexes despite high plasma motilin levels in patients with low gastric pH

Digestive Diseases and Sciences

Volumn 43, Issue 8, 1998, Pages 1697-1700

  Kusano, Motoyasu ^a,b   Sekiguchi, Toshikazu ^a   Kawamura, Osamu ^a   Kikuchi, Kazuma ^a   Nakamura, Kazumi ^a   Mori, Masatomo ^a  

^a GUNMA UNIVERSITY   (Japan)

^b GUNMA UNIVERSITY   (Japan)

Author keywords

H2 receptor antagonist; Interdigestive migrating complex; Low gastric pH; Manometry; Motilin

Indexed keywords

MOTILIN;

ADULT; ARTICLE; CASE REPORT; DYSPEPSIA; FEMALE; HUMAN; MALE; MIGRATING MYOELECTRIC COMPLEX; PATHOPHYSIOLOGY; PH MEASUREMENT; PRIORITY JOURNAL; PROTEIN SECRETION; STOMACH ACID SECRETION; STOMACH MOTILITY; STOMACH PH; STOMACH PRESSURE;

EID: 0031851473     PISSN: 01632116     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1018815215724     Document Type: Article

References (15)

1. Itoh Z: Effect of motilin on gastrointestinal motor activity in the dog. In Motilin. Z Itoh (ed). San Diego, Academic Press, 1990, pp 133-154
2. Itoh Z, Nakaya M, Suzuki T, Arai H, Wakabayashi K: Erythromycin mimics exogenous motilin in gastrointestinal contractile activity in the dog. Am J Physiol 247:G688-G694, 1984
3. Lee KY, Chang TM, Chey WY: Effect of rabbit anti-motilin serum on myoelectric activity and plasma motilin concentration in fasting dog. Am J Physiol 245:G547-G553, 1983
4. 125I-motilin to duodenal muscle. Biochem Biophys Res Commun 150:877-882, 1988
5. Satoh M, Sakai T, Sano I, Fujikura K, Koyama H, Ohshima K, Itoh S, Omura S: EM574, an erythromycin derivative, is a potent motilin receptor agonist in human gastric antrum. J Pharmacol Exp Ther 271:574-579, 1994
6. Labo G, Bortolotti M, Vezzadini P, Bonora G, Bersani G: Interdigestive gastroduodenal motility and scrum motilin levels in patients with idiopathic delay in gastric emptying. Gastroenterology 90:20-26, 1986
7. Kusano M, Sekiguchi T, Kawamura O, Kikuchi K, Miyazaki M, Horikoshi T, Tsunoda T, Mori M: Further classification of dysmotility-like dyspepsia by interdigestive gastroduodenal manometry and plasma niotilin level. Am J Gastroenterol 92:481-484, 1947
8. Kusano M, Sekiguchi T, Nishioka T, Kawamura O, Kikuchi K, Matsuzaki T, Horikoshi T: Gastric acid inhibits antral phase III activity in duodenal ulcer patients. Dig Dis Sci 38:824-831, 1993
9. Arndorfer RC, Stef JJ, Dodds WJ, Linehan JH, Hogan WJ: Improved infusion system for intraluminal esophageal manometry. Gastroenterology 73:23-27, 1977
10. Shima K, Shin S, Tanaka A, Hashimura E, Nishino T, Imagawa K, Kumahara Y, Yanaihara N: Heterogeneity of plasma motilin in patients with chronic renal failure. Horm Metab Res 12:328-331, 1980
11. Wilmer A, Tack J, Coremans G, Janssens J, Peeters T, Vantrappen G: 5-Hydroxytryptamine-3 receptors are involved in the initiation of gastric phase-3 motor activity in humans. Gastroenterology 105:773-780, 1993
12. Achem-Karam SR, Funakoshi A, Vinik AI, Owyang C: Plasma motilin concentration and interdigestive migrating motor complex in diabetic gastroparesis: Effect of metoclopramide. Gastroenterology 88:492-499, 1985
13. Bortolotti M, Frada G, Vezzadini P, Bonora G, Barbagallo-Sangiorgi B, Labo G: Influence of gastric acid secretion on interdigestive gastric motor activity and serum motilin in the elderly. Digestion 38:226-233, 1987
14. Besterman HS, Mallinson CN, Modigliani R, Christofides ND, Pera A, Ponti V, Sarson DL, Bloom SR: Gut hormones in inflammatory bowel disease. Scand J Gastroenterol 18:845-852, 1983
15. Yamamoto O, Matsunaga Y, Haga N, Mizumoto A, Itoh Z: Inhibition of phase III activity by acidifiying stomach in vagally denervated and innervated dogs with gastric pouches. Gastroenterology 106:1533-1541, 1994