Chromogranin A measurement in neuroendocrine tumors

International Journal of Biological Markers

Volumn 13, Issue 1, 1998, Pages 3-9

  Ferrari, L ^a   Seregni, E ^a   Martinetti, A ^a   Van Graafeiland, B ^a   Nerini Molteni, S ^a   Botti, C ^a   Artale, S ^a   Cresta, S ^a   Bombardieri, E ^a  

^a NATIONAL CANCER INSTITUTE   (Italy)

Author keywords

Carcinoids; Chromogranin A; Gastroenteropancreatic tumors; Medullary thyroid carcinoma; Neuroblastoma; Neuroendocrine tumors; Pheochromocytoma; Small cell lung cancer; Tumor markers

Indexed keywords

CHROMOGRANIN A; GLYCOPROTEIN; TUMOR MARKER;

ARTICLE; FOLLOW UP; HUMAN; NEUROENDOCRINE TUMOR; PROGNOSIS; TREATMENT PLANNING;

EID: 0031849286     PISSN: 03936155     EISSN: None     Source Type: Journal    
DOI: 10.1177/172460089801300102     Document Type: Article

References (47)

1. Neary PC, Redmond PH, Houghton T, Watson GRK, Bouchier-Hayes D. Carcinoid disease. Review of the literature. Dis Colon Rectum 1997; 40: 349-62.
2. Capella C, Heitz PU, Höfler H, Solcia E, Klöppel G. Revised classification of neuroendocrine tumours of the lung, pancreas and gut. Virchows Archiv 1995; 425: 547-60.
3. Hauser H, Wolf G, Uranüs S, Klimpfinger M. Neuroendocrine tumours in various organ systems in a ten-year period. Eur J Surgical Oncol 1995; 21: 297-300.
4. Feldman JM. Carcinoid tumors and syndrome. Semin Oncol 1987; 14: 237-46.
5. Wolfe MM, Jensen RT. Zollinger-Ellison syndrome. Current concepts in diagnosis and management. N Engl J Med 1987; 317: 1200-09.
6. Vinik AI, Gonin J, England BJ, Jackson T, McLeod MK. Plasma substance-P in neuroendocrine tumors and idiopathic flushing: the value of pentagastrin stimulation tests and the effects of somatostatin analog. J Clin Endocrinol Metab 1990; 70: 1702-09.
7. Danforth DN Jr, Gorden P, Brennan MF. Metastatic insulin-secreting carcinoma of the pancreas: clinical course and the role of surgery. Surgery 1984; 96: 1027-37.
8. O'Connor DT, Deftos LJ. Secretion of chromogranin A by peptide-producing endocrine neoplasms. N Engl J Med 1986; 314: 1145-51.
9. Eriksson B, Arnberg H, Öberg K, et al. Chromogranins - New sensitive markers for neuroendocrine tumors. Acta Oncol 1989; 28: 325-9.
10. Gerbitz KD, Summer J, Schumacher I, Arnold H, Kraft A, Mross K. Enolase isoenzymes as tumor markers. J Clin Chem Clin Biochem 1986; 24: 1009-16.
11. Prinz RA, Marangos PJ. Use of neuron-specific enolase as serum marker for neuroendocrine neoplasms. Surgery 1982; 92: 887-9.
12. Huttner WB, Gerdes HH, Rosa P. The granin (chromogranin/secretogranin) family. TIBS 1991; 16: 27-30.
13. Cohn DV, Elting JJ, Frick M, Elde R. Selective localization of the parathyroid secretory protein I/adrenal medulla chromogranin A protein family in a wide variety of endocrine cells of the rat. Endocrinol 1984; 114: 1963-74.
14. Hendy GN, Bevan S, Mattei MG, Mouland AJ. Review: Chromogranin A. Clin Invest Med 1995; 18: 47-65.
15. Hutton JC, Davidson HW, Peshavaria M. Proteolytic processing of chromogranin A in purified insulin granules. Biochem J 1987; 244: 457-64.
16. Barbosa JA, Gill BM, Takiyyuddin MA, O'Connor DT. Chromogranin A: Posttranslational modifications in secretory granules. Endocrinol 1991; 128: 174-90.
17. Sanchez-Margalet V, Lucas M, Goberna R. Pancreastatin: Further evidence for its consideration as a regulatory peptide. J Molec Endocrinol 1996; 16: 1-8.
18. Kirchmair R, Leitner B, Fischer-Colbrie R, Marksteiner J, Hogue-Angeletti R, Winkler H. Large variations in the proteolytic formation of a chromogranin A-derived peptide (GE-25) in neuroendocrine tissues. Biochem J 1995; 310: 331-6.
19. Simon J-P, Bader M-F, Aunis D. Secretion from chromaffin cells is controlled by chromogranin A-derived peptides. Proc Natl Acad Sci USA 1988; 85: 1712-6.
20. Benedum UM, Baeuerle PA, Konecki DS, et al. The primary structure of bovine chromogranin A: a representative of a class of acidic secretory proteins common to a variety of peptidergic cells. EMBO J 1986; 5: 1495-502.
21. Winkler H, Apps DK, Fischer-Colbrie R. The molecular function of adrenal chromaffin granules: established facts and unresolved topics. Neuro science 1986; 18: 261-90.
22. Falkensammer G, Fischer-Colbrie R, Winkler H. Biogenesis of chromaffin granules: incorporation of sulfate into chromogranin B and into a proteoglycan. J Neurochem 1985; 45: 1475-80.
23. Modlin IM, Tang LH. Approaches to the diagnosis of gut neuroendocrine tumours: the last word (today). Gastroenterol 1997; 112: 583-90.
24. Sakamoto T, Miyata M, Izukura M, et al. Role of endogenous somatostatin in postprandial hypersecretion of neurotensin in patients after gastrectomy. Ann Surg 1997; 225: 377-81.
25. Eriksson B, Öberg K. Peptide hormones as tumor markers in neuroendocrine gastrointestinal tumors. Acta Oncol 1991; 30: 477-83.
26. Schürmann G, Raeth U, Wiedenmann B. Serum chromogranin A in the diagnosis and follow-up of neuroendocrine tumors of the gastroenteropancreatic tract. World J Surg 1992; 16: 697-702.
27. Haller DG. Endocrine tumors of the gastrointestinal tract. Curr Opinion Oncol 1994; 6: 72-6.
28. Öberg K. Neuroendocrine gastrointestinal tumours. Ann Oncol 1996; 7: 453-63.
29. Nobels FRE, Kwekkeboom DJ, Coopmans W, et al. Chromogranin A as serum marker for neuroendocrine neoplasia: comparison with neuron-specific enolase and the α-subunit of glycoprotein hormones. J Clin Endocrinol Metab 1997; 82: 2622-8.
30. Janson ET, Holmberg L, Stridsberg M, et al. Carcinoid tumors: Analysis of prognostic factors and survival in 301 patients from a referral center. Ann Oncol 1997; 8: 685-90.
31. Nanes MS, O'Connor DT, Marx SJ. Plasma chromogranin A in primary hyperparathyroidism. J Clin Endocrinol Metab 1989; 320: 444-7.
32. Stabile BE, Howards TJ, Passaro E, O'Connor DT. Source of plasma chromogranin A elevation in gastrinoma patients. Arch Surg 1990; 125: 451-53.
33. Addis BJ. Neuroendocrine differentiation in lung carcinoma. Thorax 1995; 50: 113-15.
34. Sobol RE, O'Connor DT, Addison J, Suchocki K, Royston I, Deftos LJ. Elevated serum chromogranin A concentrations in small cell lung carcinoma. Ann Intern Med 1986; 105: 698-700.
35. Deftos LJ. Chromogranin A: its role in endocrine function and as an endocrine and neuroendocrine tumor marker. Endocr Rev 1991; 12: 181-7.
36. Johnson PWM, Joel SP, Love S, et al. Tumour markers for prediction of survival and monitoring of remission in small cell lung cancer. Br J Cancer 1993; 67: 760-6.
37. Smith AF, Winkler H. Purification and properties of an acidic protein from chromaffin granules of bovine adrenal medulla. Biochem J 1967; 103: 483-92.
38. O'Connor DT, Frigon RP, Sokoloff RL. Human chromogranin A: purification and characterization from catecholamine storage vesicles of human pheochromocytoma. Hypertension 1984; 6: 2-12.
39. O'Connor DT, Frigon RP. Chromogranin A, the major catecholamine storage vesicle soluble protein: multiple size forms, subcellular storage, and regional distribution in chromaffin and nervous tissue elucidated by radioimmunoassay. J Biol Chem 1984; 259: 3237-47.
40. Saaman NA, Hickey RC. Pheochromocytoma. Sem Oncol 1987; 14: 297.
41. O'Connor DT, Bernstein KN. Radioimmunoassay of chromogranin A in plasma as a measure of exocytotic sympathoadrenal activity in normal subjects and patients with pheochromocytoma. New Engl J Med 1984; 311: 764-70.
42. Hsiao RJ, Parmer RJ, Takiyyuddin MA, O'Connor DT. Chromogranin A storage and secretion: sensitivity and specificity for the diagnosis of pheochromocytoma. Medicine 1991; 70: 33-45.
43. Stridsberg M, Husebye ES. Chromogranin A and chromogranin B are sensitive circulating markers for phaeochromocytoma. Eur J Endocrinol 1997; 136: 67-73.
44. Hsiao RJ, Neumann HPH, Parmer RJ, Barbosa JA, O'Connor DT. Chromogranin A in familial pheochromocytoma: diagnostic screening value, prediction of tumour mass, and post-resection kinetics indicating two-compartment distribution. Am J Med 1990; 88: 607-13.
45. Hsiao RJ, Seeger RC, Yu AL, O'Connor DT. Chromogranin A in children with neuroblastoma. Serum concentration parallels disease stage and predicts survival. J Clin Invest 1990; 85: 1555-9.
46. Wassberg E, Stridsberg M, Christofferson R. Plasma levels of chromogranin A are directly proportional to tumour burden in neuroblastoma. J Endocrinol 1996; 151: 225-30.
47. Schürmann G, Betzler M, Buhr HJ. Chromogranin A, neuron-specific enolase and synaptophysin as neuroendocrine cell markers in the diagnosis of tumours of the gastro-entero-pancreatic system. Eur J Surg Oncol 1990; 16: 298-303.