-
1
-
-
0029762462
-
New directions in the drug treatment of Parkinson's disease
-
Montastruc JL, Rascol O, Senard JM. New directions in the drug treatment of Parkinson's disease. Drugs Aging 1996;9:169-84.
-
(1996)
Drugs Aging
, vol.9
, pp. 169-184
-
-
Montastruc, J.L.1
Rascol, O.2
Senard, J.M.3
-
2
-
-
0031105385
-
An overview of novel therapies for Parkinson's disease
-
Fahn S. An overview of novel therapies for Parkinson's disease. Exp Neurol 1997;144:21-3.
-
(1997)
Exp Neurol
, vol.144
, pp. 21-23
-
-
Fahn, S.1
-
3
-
-
0023404750
-
Clinical pharmacokinetics of antiparkinsonian drugs
-
Cedarbaum JM. Clinical pharmacokinetics of antiparkinsonian drugs. Clin Pharmacokinet 1987;13:141-78.
-
(1987)
Clin Pharmacokinet
, vol.13
, pp. 141-178
-
-
Cedarbaum, J.M.1
-
4
-
-
0018639137
-
Levodopa with benserazide or carbidopa in Parkinson disease
-
Rinne UK, Mölsä P. Levodopa with benserazide or carbidopa in Parkinson disease. Neurology 1979;29:1584-9.
-
(1979)
Neurology
, vol.29
, pp. 1584-1589
-
-
Rinne, U.K.1
Mölsä, P.2
-
5
-
-
0023946277
-
Clinical significance of the relationship between O-methyldopa levels and levodopa intake
-
Cedarbaum JM, Kutt H, McDowell FH. Clinical significance of the relationship between O-methyldopa levels and levodopa intake. Neurology 1988;38:533-6.
-
(1988)
Neurology
, vol.38
, pp. 533-536
-
-
Cedarbaum, J.M.1
Kutt, H.2
McDowell, F.H.3
-
6
-
-
0025129116
-
Modification of central dopaminergic mechanism by continuous levodopa therapy for advanced Parkinson's disease
-
Mouradian MM, Heuser IJE, Baronti F, Chase TN. Modification of central dopaminergic mechanism by continuous levodopa therapy for advanced Parkinson's disease. Ann Neurol 1990;27:18-23.
-
(1990)
Ann Neurol
, vol.27
, pp. 18-23
-
-
Mouradian, M.M.1
Heuser, I.J.E.2
Baronti, F.3
Chase, T.N.4
-
7
-
-
0023185154
-
Peripheral pharmacokinetics of levodopa in untreated, stable and fluctuating parkinsonian patients
-
Gancher ST, Nutt JG, Woodward WR. Peripheral pharmacokinetics of levodopa in untreated, stable and fluctuating parkinsonian patients. Neurology 1987;37:940-4.
-
(1987)
Neurology
, vol.37
, pp. 940-944
-
-
Gancher, S.T.1
Nutt, J.G.2
Woodward, W.R.3
-
8
-
-
0023762236
-
Motor fluctuations in Parkinson's disease: Central pathophysiological mechanisms; I
-
Fabbrini G, Mouradian MM, Juncos JL, Schlegel JJ, Mohr E, Chase TN. Motor fluctuations in Parkinson's disease: central pathophysiological mechanisms; I. Ann Neurol 1988;24:366-71.
-
(1988)
Ann Neurol
, vol.24
, pp. 366-371
-
-
Fabbrini, G.1
Mouradian, M.M.2
Juncos, J.L.3
Schlegel, J.J.4
Mohr, E.5
Chase, T.N.6
-
9
-
-
0023711041
-
Motor fluctuations in Parkinson's disease: Central pathophysiological mechanisms; II
-
Mouradian MM, Juncos JL, Fabbrini G, Schlegel J, Bartko JJ, Chase TN. Motor fluctuations in Parkinson's disease: central pathophysiological mechanisms; II. Ann Neurol 1988;24:372-8.
-
(1988)
Ann Neurol
, vol.24
, pp. 372-378
-
-
Mouradian, M.M.1
Juncos, J.L.2
Fabbrini, G.3
Schlegel, J.4
Bartko, J.J.5
Chase, T.N.6
-
10
-
-
0016707704
-
3-O-Methyldopa inhibition of 1-dopa at the blood-brain barrier
-
Wade LA, Katzman R. 3-O-Methyldopa inhibition of 1-dopa at the blood-brain barrier. Life Sci 1975;17:131-6.
-
(1975)
Life Sci
, vol.17
, pp. 131-136
-
-
Wade, L.A.1
Katzman, R.2
-
11
-
-
0028898323
-
Concentration-effect relationship of levodopa in patients with Parkinson's disease after oral administration of an immediate release and a controlled release formulation
-
Harder S, Baas H, Bergemann N, Demisch L, Rietbrock S. Concentration-effect relationship of levodopa in patients with Parkinson's disease after oral administration of an immediate release and a controlled release formulation. Br J Clin Pharmacol 1995;39:39-44.
-
(1995)
Br J Clin Pharmacol
, vol.39
, pp. 39-44
-
-
Harder, S.1
Baas, H.2
Bergemann, N.3
Demisch, L.4
Rietbrock, S.5
-
12
-
-
0025869874
-
Temporal relationships between plasma and cerebrospinal fluid pharmacokinetics of levodopa and clinical effects in Parkinson's disease
-
Olanow CW, Gauger LL, Cederbaum JM. Temporal relationships between plasma and cerebrospinal fluid pharmacokinetics of levodopa and clinical effects in Parkinson's disease. Ann Neurol 1991;29:556-9.
-
(1991)
Ann Neurol
, vol.29
, pp. 556-559
-
-
Olanow, C.W.1
Gauger, L.L.2
Cederbaum, J.M.3
-
13
-
-
0026724717
-
A 3-O-methyldopa administration does not alter fluorodopa transport into the brain
-
Guttman M, Léger G, Ceberbaum JM, Reches A, Woodward W, Evans A, et al. A 3-O-methyldopa administration does not alter fluorodopa transport into the brain. Ann Neurol 1992;31:628-43.
-
(1992)
Ann Neurol
, vol.31
, pp. 628-643
-
-
Guttman, M.1
Léger, G.2
Ceberbaum, J.M.3
Reches, A.4
Woodward, W.5
Evans, A.6
-
14
-
-
0020045716
-
3-O-Methyldopa inhibits rotations induced by levodopa in rats after unilateral destruction of the nigrostriatal pathway
-
Reches A, Mielke LR, Fahn S. 3-O-Methyldopa inhibits rotations induced by levodopa in rats after unilateral destruction of the nigrostriatal pathway. Neurology 1982;32:887-8.
-
(1982)
Neurology
, vol.32
, pp. 887-888
-
-
Reches, A.1
Mielke, L.R.2
Fahn, S.3
-
15
-
-
0023809040
-
Properties of novel effective and highly selective inhibitors of catechol-O-methyltransferase
-
Männistö PT, Kaakkola S, Nissinen E, Linden IB, Pohto P. Properties of novel effective and highly selective inhibitors of catechol-O-methyltransferase. Life Sci 1988;43:1465-71.
-
(1988)
Life Sci
, vol.43
, pp. 1465-1471
-
-
Männistö, P.T.1
Kaakkola, S.2
Nissinen, E.3
Linden, I.B.4
Pohto, P.5
-
16
-
-
0028203007
-
Inhibition of soluble catechol-O-methyltransferase and single-dose pharmacokinetics after oral and intravenous administration of entacapone
-
Keränen T, Gordin A, Karlsson M, Korpela K, Pentikäinen PJ, Rita H, et al. Inhibition of soluble catechol-O-methyltransferase and single-dose pharmacokinetics after oral and intravenous administration of entacapone. Eur J Clin Pharmacol 1994;46:151-7.
-
(1994)
Eur J Clin Pharmacol
, vol.46
, pp. 151-157
-
-
Keränen, T.1
Gordin, A.2
Karlsson, M.3
Korpela, K.4
Pentikäinen, P.J.5
Rita, H.6
-
17
-
-
0028286186
-
Effect of peripheral catechol-O-methyltransferase inhibition on the pharmacokinetics and pharmacodynamics of levodopa in parkinsonian patients
-
Nutt JG, Woodward WR, Becker RM, Stone CK, Berggren K, Carter JH et al. Effect of peripheral catechol-O-methyltransferase inhibition on the pharmacokinetics and pharmacodynamics of levodopa in parkinsonian patients. Neurology 1994;44:913-9.
-
(1994)
Neurology
, vol.44
, pp. 913-919
-
-
Nutt, J.G.1
Woodward, W.R.2
Becker, R.M.3
Stone, C.K.4
Berggren, K.5
Carter, J.H.6
-
18
-
-
0028137620
-
Effect of entacapone, a peripherally acting catechol-O-methyltransferase inhibitor, on the motor response to acute treatment with levodopa in patients with Parkinson's disease
-
Merello M, Lees AJ, Webster R, Bovingdon M, Gordin A. Effect of entacapone, a peripherally acting catechol-O-methyltransferase inhibitor, on the motor response to acute treatment with levodopa in patients with Parkinson's disease. J Neurol Neurosurg Psychiatry 1994;57:186-9.
-
(1994)
J Neurol Neurosurg Psychiatry
, vol.57
, pp. 186-189
-
-
Merello, M.1
Lees, A.J.2
Webster, R.3
Bovingdon, M.4
Gordin, A.5
-
19
-
-
0029881772
-
Effect of one month's treatment with peripherally-acting catechol-O-methyltransferase inhibitor, entacapone, on pharmacokinetics and motor response to levodopa in advanced parkinsonian patients
-
Ruottinen H, Rinne UK. Effect of one month's treatment with peripherally-acting catechol-O-methyltransferase inhibitor, entacapone, on pharmacokinetics and motor response to levodopa in advanced parkinsonian patients. Clin Neuropharmacol 1996;19:222-33.
-
(1996)
Clin Neuropharmacol
, vol.19
, pp. 222-233
-
-
Ruottinen, H.1
Rinne, U.K.2
-
20
-
-
0029895288
-
A double-blind pharmacokinetic and clinical dose-response study of entacapone as an adjuvant to levodopa therapy in advanced Parkinson's disease
-
Ruottinen HM, Rinne UK. A double-blind pharmacokinetic and clinical dose-response study of entacapone as an adjuvant to levodopa therapy in advanced Parkinson's disease. Clin Neuropharmacol 1996;19:283-96.
-
(1996)
Clin Neuropharmacol
, vol.19
, pp. 283-296
-
-
Ruottinen, H.M.1
Rinne, U.K.2
-
21
-
-
0026566932
-
Liquid Chromatographic determination of a new catechol-O-methyltransferase inhibitor, entacapone, and its Z-isomer in human plasma and urine
-
Karlsson M, Wikberg T. Liquid Chromatographic determination of a new catechol-O-methyltransferase inhibitor, entacapone, and its Z-isomer in human plasma and urine. J Pharm Biomed Anal 1992;10:593-600.
-
(1992)
J Pharm Biomed Anal
, vol.10
, pp. 593-600
-
-
Karlsson, M.1
Wikberg, T.2
-
22
-
-
0021783191
-
Le test à la L-Dopa dans la maladie de Parkinson
-
Esteguy M, Bonnet AM, Kefalos J, Lhermitte F, Agid Y. Le test à la L-Dopa dans la maladie de Parkinson. Rev Neurol 1985;141:413-5.
-
(1985)
Rev Neurol
, vol.141
, pp. 413-415
-
-
Esteguy, M.1
Bonnet, A.M.2
Kefalos, J.3
Lhermitte, F.4
Agid, Y.5
-
23
-
-
0018394195
-
Simultaneous modeling of pharmacokinetics and pharmacodynamics: Application to d-tubocurarine
-
Sheiner LB, Stanski DR, Vozeh S, Miller RD, Ham J. Simultaneous modeling of pharmacokinetics and pharmacodynamics: application to d-tubocurarine. Clin Pharmacol Ther 1979;25:358-71.
-
(1979)
Clin Pharmacol Ther
, vol.25
, pp. 358-371
-
-
Sheiner, L.B.1
Stanski, D.R.2
Vozeh, S.3
Miller, R.D.4
Ham, J.5
-
24
-
-
0027049043
-
Building population pharmacokinetic-pharmacodynamic models; I: Models for covariate effects
-
Mandema JW, Verotta D, Sheiner LB. Building population pharmacokinetic-pharmacodynamic models; I: models for covariate effects. J Pharmacokinet Biopharm 1992;20:511-28.
-
(1992)
J Pharmacokinet Biopharm
, vol.20
, pp. 511-528
-
-
Mandema, J.W.1
Verotta, D.2
Sheiner, L.B.3
-
25
-
-
0003747347
-
-
San Francisco: NONMEM Project Group, University of California, San Francisco
-
Beal SL, Sheiner LB, editors. NONMEM users guides. San Francisco: NONMEM Project Group, University of California, San Francisco; 1992.
-
(1992)
NONMEM Users Guides
-
-
Beal, S.L.1
Sheiner, L.B.2
-
26
-
-
0003287188
-
Xpose: An Splus based model building aid for population analysis with NONMEM
-
Aarons L, Balant LP, Danhof M, et al, editors. Brussels: European Commission
-
Jonsson EN, Karlsson MO. Xpose: an Splus based model building aid for population analysis with NONMEM. In: Aarons L, Balant LP, Danhof M, et al, editors. The population approach: measuring and managing variability in response, concentration and dose. Brussels: European Commission; 1997.
-
(1997)
The Population Approach: Measuring and Managing Variability in Response, Concentration and Dose
-
-
Jonsson, E.N.1
Karlsson, M.O.2
-
27
-
-
0027715858
-
The importance of modelling interoccasion variability in population pharmacokinetic analyses
-
Karlsson MO, Sheiner LB. The importance of modelling interoccasion variability in population pharmacokinetic analyses. J Pharmacokinet Biopharm 1993;21:735-50.
-
(1993)
J Pharmacokinet Biopharm
, vol.21
, pp. 735-750
-
-
Karlsson, M.O.1
Sheiner, L.B.2
-
30
-
-
0024521415
-
Pharmacokinetic and pharmacodynamic modeling of L-dopa plasma concentrations and clinical effects in Parkinson's disease after Sinemet
-
Nelson MV, Berchou RC, Lewitt PA, Kareti D, Kesaree N, Schlick P, et al. Pharmacokinetic and pharmacodynamic modeling of L-dopa plasma concentrations and clinical effects in Parkinson's disease after Sinemet. Neuropharmacology 1989;12:91-7.
-
(1989)
Neuropharmacology
, vol.12
, pp. 91-97
-
-
Nelson, M.V.1
Berchou, R.C.2
Lewitt, P.A.3
Kareti, D.4
Kesaree, N.5
Schlick, P.6
-
31
-
-
0027477017
-
Pharmacodynamic modeling of oral levodopa: Clinical application in Parkinson's disease
-
Contin M, Riva R, Martinelli P, Cortelli P, Albani F, Baruzzi A. Pharmacodynamic modeling of oral levodopa: clinical application in Parkinson's disease. Neurology 1993;43:367-71.
-
(1993)
Neurology
, vol.43
, pp. 367-371
-
-
Contin, M.1
Riva, R.2
Martinelli, P.3
Cortelli, P.4
Albani, F.5
Baruzzi, A.6
-
32
-
-
0027930341
-
Longitudinal monitoring of the levodopa concentration-effect relationship in Parkinson's disease
-
Contin M, Riva R, Martinelli P, Cortelli P, Albani F, Baruzzi A. Longitudinal monitoring of the levodopa concentration-effect relationship in Parkinson's disease. Neurology 1994;44:1287-92.
-
(1994)
Neurology
, vol.44
, pp. 1287-1292
-
-
Contin, M.1
Riva, R.2
Martinelli, P.3
Cortelli, P.4
Albani, F.5
Baruzzi, A.6
-
33
-
-
0029764853
-
Population pharmacokinetics and pharmacodynamics of oral levodopa in parkinsonian patients
-
Triggs EJ, Charles BG, Contin M, Martinelli P, Cortelli P, Riva R, et al. Population pharmacokinetics and pharmacodynamics of oral levodopa in parkinsonian patients. Eur J Clin Pharmacol 1996;51:59-67.
-
(1996)
Eur J Clin Pharmacol
, vol.51
, pp. 59-67
-
-
Triggs, E.J.1
Charles, B.G.2
Contin, M.3
Martinelli, P.4
Cortelli, P.5
Riva, R.6
-
34
-
-
0029883235
-
The response to levodopa in Parkinson's disease: Imposing pharmacological law and order
-
Nutt JG, Holford NHG. The response to levodopa in Parkinson's disease: imposing pharmacological law and order. Ann Neurol 1996;39:561-73.
-
(1996)
Ann Neurol
, vol.39
, pp. 561-573
-
-
Nutt, J.G.1
Holford, N.H.G.2
-
35
-
-
0025162198
-
Pharmacodynamic modeling of concentration-effect relationships after controlled-release carbidopa/levodopa (Sinemet CR4) in Parkinson's disease
-
Nelson MV, Berchou RC, LeWitt PA, Kareti D, Galloway MP. Pharmacodynamic modeling of concentration-effect relationships after controlled-release carbidopa/levodopa (Sinemet CR4) in Parkinson's disease. Neurology 1990;40:70-4.
-
(1990)
Neurology
, vol.40
, pp. 70-74
-
-
Nelson, M.V.1
Berchou, R.C.2
LeWitt, P.A.3
Kareti, D.4
Galloway, M.P.5
-
36
-
-
0028838259
-
Concentration-effect relationship of levodopa in patients with Parkinson's disease
-
Harder S, Baas H, Rietbrock S. Concentration-effect relationship of levodopa in patients with Parkinson's disease. Clin Pharmacokinet 1995;29:243-56.
-
(1995)
Clin Pharmacokinet
, vol.29
, pp. 243-256
-
-
Harder, S.1
Baas, H.2
Rietbrock, S.3
-
37
-
-
0025803672
-
Central action of benserazide after COMT inhibition demonstrated in vivo by PET
-
Tedroff J, Hartvig P, Bjurling P, Andersson Y, Antoni G, Långström B. Central action of benserazide after COMT inhibition demonstrated in vivo by PET. J Neural Transm 1991;85:11-7.
-
(1991)
J Neural Transm
, vol.85
, pp. 11-17
-
-
Tedroff, J.1
Hartvig, P.2
Bjurling, P.3
Andersson, Y.4
Antoni, G.5
Långström, B.6
|