Exhaustive exercise-induced tissue hypoxia does not change endothelin and big endothelin plasma levels in normal volunteers

American Journal of Hypertension

Volumn 11, Issue 8 I, 1998, Pages 1028-1031

  Lenz, Tomas ^a   Nadansky, Markus ^a   Gossmann, Jan ^a   Oremek, Gerhard ^a   Geiger, Helmut ^a  

^a GOETHE UNIVERSITY   (Germany)

Author keywords

Endothelin; Exercise; Hypoxia

Indexed keywords

ADRENALIN; BIG ENDOTHELIN 1; DIPEPTIDYL CARBOXYPEPTIDASE; ENDOTHELIN 1; LACTIC ACID; NORADRENALIN; RENIN;

ADRENALIN BLOOD LEVEL; ADULT; ARTICLE; BLOOD PRESSURE REGULATION; CONTROLLED STUDY; EXERCISE; EXHAUSTION; FEMALE; HORMONE RELEASE; HUMAN; HUMAN EXPERIMENT; HYPOXEMIA; LACTATE BLOOD LEVEL; MALE; NORADRENALIN BLOOD LEVEL; NORMAL HUMAN; PLASMA RENIN ACTIVITY; PRIORITY JOURNAL; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM;

ADULT; CELL HYPOXIA; ENDOTHELIN-1; ENDOTHELINS; EXERCISE; FEMALE; HUMANS; MALE; PROTEIN PRECURSORS; RENIN;

EID: 0031847011     PISSN: 08957061     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0895-7061(98)00086-7     Document Type: Article

References (24)

1. Kohan DE: Endothelins in the kidney: physiology and pathophysiology. Am J Kidney Dis 1993;22:493-510.
2. Levin ER: Endothelins. N Engl J Med 1995;333:356-363.
3. Predel HG, Meyer-Lehnert H, Backer A, et al: Plasma concentrations of endothelin in patients with abnormal vascular reactivity. Effects of ergometric exercise and acute saline loading. Life Sci 1990;47:1837-1843.
4. McMurray JJ, Ray SG, Abdullah I, et al: Plasma endothelin in chronic heart failure. Circulation 1992;85: 1374-1379.
5. Miyauchi T, Yanagisawa M, Tomizawa T, et al: Increased plasma concentrations of endothelin-1 and big endothelin-1 in acute myocardial infarction. Lancet 1989;2:53-54.
6. Ferri C, Bellini C, De Angelis C, et al: Circulating endothelin concentrations in patients with chronic hypoxia. J Clin Pathol 1995;48:519-524.
7. Li H, Chen SJ, Chen YF, et al: Enhanced endothelin-1 and endothelin receptor gene expression in chronic hypoxia. J Appl Physiol 1994;77:1451-1459.
8. Maeda S, Miyauchi T, Goto K, Matsuda M: Alteration of plasma endothelin-1 by exercise at intensities lower and higher than ventilatory threshold. J Appl Physiol 1994;77:1399-1402.
9. Rocker L, Mockel M, Westpfahl KP, Gunga HC: Influence of maximal ergometric exercise on endothelin concentrations in relation to molecular markers of the hemostatic system. Throm Haemost 1996;75:612-616.
10. Cozenzi A, Sacerdote A, Bocin E, et al: Neither physical exercise nor alpha-1- and β-adrenergic blockade affect plasma endothelin concentrations. Am J Hypertens 1996;9:819-822.
11. Maeda S, Miyauchi T, Waku T, et al: Plasma endothelin-1 level in athletes after exercise in a hot environment: exercise-induced dehydration contributes to increase in plasma endothelin-1. Life Sci 1996;58:1259-1268.
12. Letizia C, Barilla F, Cerci S, et al: Dynamic exercise induces elevation of plasma levels of endothelin-1 in patients with coronary artery disease. Angiology 1995; 46:819-826.
13. Predel HG, Knigge H, Prinz U, et al: The exercise-induced increase in plasma levels of endothelin-1 is enhanced in patients with atherosclerotic coronary artery disease. Modulation by PETN. Agents Actions 1995;45:219-225.
14. Kullmer T, Jungmann E, Haak T, Usadel KH: Modification of the response of endothelin-1 to exhaustive physical exercise under simulated high altitude conditions with acute hypoxia. Metabolism 1995;44:8-9.
15. Richter EA, Emmeluth C, Bie P, et al: Biphasic response of plasma endothelin-1 concentration to exhaustive submaximal exercise in man. Clin Physiol 1994;14:379-384.
16. Vuolteenaho O, Koistinen P, Martikkala V, et al: Effect of physical exercise in hypobaric conditions on atrial natriuretic peptide secretion. Am J Physiol 1992;263: R647-R652.
17. Letizia C, Barilla F, Cerci S, et al: Plasma endothelin-1 concentrations in patients with coronary artery disease during stress test before and after nisoldipine administration. Acta Cardiol 1996;51:165-172.
18. de Groote P, Maillaire A, Racadot A, et al: Plasma levels of endothelin-1 at rest and after exercise in patients with moderate congestive heart failure. Int J Cardiol 1995;51:267-272.
19. Emori T, Hirata Y, Ohta K, et al: Cellular mechanism of endothelin-1 release by angiotensin and vasopressin. Hypertension 1991;18:165-170.
20. Yanagisawa M, Kurihara H, Kimura S, et al: A novel potent vasoconstrictor peptide produced by vascular endothelial cells. Nature 1988;332:411-415.
21. Haller H, Lenz T, Thiede HM, et al: Platelet intracellular free calcium during dynamic exercise. Am J Nephrol 1986;6(suppl 1):57-59.
22. Takahashi H, Irizawa M, Komura T, et al: Relationship among blood lactate and plasma catecholamine levels during exercise in acute hypoxia. Appl Human Sci 1995;14:49-53.
23. Maeda S, Miyauchi T, Sakane M, et al: Does endothelin-1 participate in the exercise-induced changes of blood flow distribution of muscles in humans? J Appl Physiol 1997;82:1107-1111.
24. Lenz T, Thiede HM, Nussberger J, et al: Hyperreninemia and secondary hyperaldosteronism in a patient with pheochromocytoma and von Hippel Lindau disease. Nephron 1992;62:345-350.