Effect of long-term recombinant growth hormone therapy in children - The National Cooperative Growth Study, USA, 1985-1994

Journal of Pediatric Endocrinology and Metabolism

Volumn 11, Issue 3, 1998, Pages 403-412

  Root, Allen W ^a,d   Kemp, Stephen F ^b   Rundle, Amy C ^c   Dana, Kenneth ^c   Attie, Kenneth M ^c  

^a UNIVERSITY OF SOUTH FLORIDA   (United States)

^b UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

^c GENENTECH INC   (United States)

^d JOHNS HOPKINS ALL CHILDREN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

RECOMBINANT GROWTH HORMONE;

ADOLESCENT; ARTICLE; CHILD; CHILD GROWTH; DRUG EFFICACY; DRUG RESPONSE; FEMALE; GROWTH HORMONE BLOOD LEVEL; GROWTH HORMONE DEFICIENCY; GROWTH RATE; HORMONAL THERAPY; HUMAN; MAJOR CLINICAL STUDY; MALE; SHORT STATURE; TURNER SYNDROME;

EID: 0031846497     PISSN: 0334018X     EISSN: None     Source Type: Journal    
DOI: 10.1515/JPEM.1998.11.3.403     Document Type: Article

References (31)

1. Rabin MS. Treatment of a pituitary dwarf with human growth hormone. J Clin Endocrinol Metab 1958; 18: 901-903.
2. Brown P, Gadjusek DC, Gibbs DC Jr, Aser DM. Potential epidemic of Creutzfeldt-Jakob disease from human growth hormone therapy. N Engl J Med 1985; 313: 728-731.
3. Frasier SD. Human pituitary growth hormone therapy in growth hormone deficiency. Endocr Rev 1983; 4: 155-170.
4. Jorgensen JOL. Human growth hormone replacement therapy: Pharmacological and clinical aspects. Endocr Rev 1991; 12: 189-207.
5. Kaplan SL, Underwood LE, August GP, Bell JJ, Blethen SL, Blizzard RM, Brown DR, Foley TP, Hintz RL, Hopwood NJ, Johanson A, Kirkland RT, Plotnick LP, Rosenfeld RG, Van Wyk JJ. Clinical studies with recombinant-DNA-methionyl growth hormone in growth hormone deficient children. Lancet 1986; 1: 697-700.
6. August GP, Lippe BM, Blethen SL, Rosenfeld RG, Seelig SA, Johanson AJ, Compton PG, Frane JW, McClellan BH, Sherman BM. Growth hormone treatment in the United States: Demographic and diagnostic features of 2331 children. J Pediatr 1990; 116: 899-903.
7. Blethen SL, Compton P, Lippe BM, Rosenfeld RG, August GP, Johanson A. Factors predicting the response to growth hormone (GH) therapy in prepubertal children with GH deficiency. J Clin Endocrinol Metab 1993; 76: 574-579.
8. Ranke MB. Toward a consensus on the diagnosis of idiopathic short stature. Horm Res 1996; 45 (Suppl 2): 64-66.
9. Hamill PVV, Drizd TA, Johnson CL, Reed RB, Roche AF, Moore WM. Physical growth: National Center for Health Statistics percentiles. Am J Clin Nutr 1979; 32: 607-629.
10. Tanner JM, Davies PW. Clinical longitudinal standards for height and height velocity in North American children. J Pediatr 1985; 107: 317-329.
11. Tanner JM. Use and abuse of growth standards. In: Falkner F, Tanner JM, eds, Human Growth. A Comprehensive Treatise, 2nd Ed, Volume 3. New York: Plenum Press, 1986; 95-109.
12. Celniker AC, Chen AB, Wert RM Jr, Sherman BM. Variability in the quantitation of circulating growth hormone using commercial immunoassays. J Clin Endocrinol Metab 1989; 68: 469-476.
13. Marin GA, Domene HM, Barnes KM, Blackwell BJ, Cassorla FG, Cutler GB Jr. The effects of estrogen priming and puberty on the growth hormone response to standardized treadmill exercise and arginine-insulin in normal girls and boys. J Clin Endocrinol Metab 1994; 79:537-541.
14. Ranke MB, Guilbaud O. Growth response in prepubertal children with idiopathic growth hormone deficiency during the first two years of treatment with human growth hormone. Analysis of the Kabi Pharmacia International Growth Study. Acta Paediatr Scand 1991; Suppl 379: 109-115.
15. Schwartz ID, Hu C-S, Shulman DI, Root AW, Bercu, BB. Linear growth response to exogenous growth hormone (GH) in children with short stature. Am J Dis Child 1990; 144: 1092-1097.
16. Albertsson-Wikland K, Westphal O, Westgren U. Daily administration of human growth hormone in growth hormone deficient children. Acta Paediatr Scand 1986; 75: 89-57.
17. Kastrup KW, Christiansen JS, Anderson JK, Orskov H. Increased growth rate following transfer to daily sc administration from three weekly injections of hGH in growth hormone deficient children. Acta Endocrinol (Copenh) 1983; 104: 148-152.
18. Rosenbloom AL, Knuth C, Shulman D. Growth hormone by daily injection in patients previously treated for growth hormone deficiency. Southern Med J 1990; 83: 653-655.
19. MacGillivray MH, Baptista J, Johanson A. Outcome of a four-year randomized study of daily versus three times weekly somatotropin treatment in prepubertal naive growth hormone-deficient children. J Clin Endocrinol Metab 1996; 81: 1806-1809.
20. Allen DB, Brook CGD, Bridges NA, Hindmarsh PC, Guyda HJ, Frazier D. Therapeutic controversies: Growth hormone (GH) treatment of non-GH deficient subjects. J Clin Endocrinol Metab 1994; 79: 1239-1248.
21. Price DA. Spontaneous adult height in patients with idiopathic short stature. Horm Res 1996; 45 (Suppl 2): 59-63.
22. Guyda HJ. Use of growth hormone in children with short stature and normal growth hormone secretion. A growing problem. Trends Endocrinol Metab 1994; 5: 334-340.
23. Wit J-M, Boersma B, de Muinck Keizer-Schrama SMPF, Nienhuis HE, Oostdijk W, Otten BJ, Delemarre-Van de Waal HA, Reeser M, Waelkens JJ, Rikken B. Long-term results of growth hormone therapy in children with short stature, subnormal growth rate and normal growth hormone response to secretagogues. Clin Endocrinol 1995; 42: 365-372.
24. Hindmarsh PC, Brook CGD. Final height of short normal children treated with growth hormone. Lancet 1996; 348: 13-16.
25. Loche S, Cambiaso P, Setzu S, Carta D, Marini R, Borrelli P, Cappa M. Final height after growth hormone therapy in non-growth-hormone-deficient children with short stature. J Pediatr 1994; 125: 196-200.
26. Kawai M, Momoi T, Yorifuji T, Yamanaka C, Sasaki H, Furusho K. Unfavorable effects of growth hormone therapy on the final height of boys with short stature not caused by growth hormone deficiency. J Pediatr 1997; 130: 205-209.
27. Rosenfeld RG, Attie KM, Frane J, Brasel JA, Burstein S, Cara JF, Chernausek S, Gotlin RW, Kuntze J, Lippe BM, Mahoney PC, Moore WV, Saenger P, Johanson AJ. Growth hormone therapy of Turner syndrome: Beneficial effect on adult height. J Pediatr in press.
28. Van den Broeck J, Massa GG, Attanasio A, Matranga A, Chaussain J-L, Price DA, Aarskog D, Wit J-M, and the European Study Group. Final height after long-term growth hormone treatment in Turner syndrome. J Pediatr 1995; 127: 729-735.
29. Rosenfeld RG, Albertsson-Wikland K, Cassorla F, Frasier SD, Hasegawa Y, Hintz RL, LaFranchi S, Lippe B, Loriaux L, Melmed S, Preece MA, Ranke MB, Reiter EO, Rogol AD, Underwood LE, Werther GA. Diagnostic controversy: The diagnosis of growth hormone deficiency revisited. J Clin Endocrinol Metab 1995; 80: 1532-1540.
30. Rosenfeld RG. Is growth hormone just a tall story? J Pediatr 1997; 130: 172-174.
31. Blethen SL, Allen DB, Graves D, August G, Moshang T, Rosenfeld R. Safety of recombinant DNA-derived growth hormone (rhGH): The National Cooperative Growth Study experience. J Clin Endocrinol Metab 1996; 81: 1704-1710.