Production of Nocardicyclins by clinical isolates of Nocardia pseudobrasiliensis and in vivo antitumor activity of the antibiotic

Journal of Antibiotics

Volumn 51, Issue 6, 1998, Pages 589-591

  Tanaka, Yasushi ^a   Gräefe, Udo ^b   Yazawa, Katsukiyo ^a   Mikami, Yuzuru ^a  

^a CHIBA UNIVERSITY   (Japan)

^b HANS KNÖLL INSTITUTE   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC ANTIBIOTIC; DOXORUBICIN; NOCARDICYCLIN A; NOCARDICYCLIN B; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBIOTIC BIOSYNTHESIS; ANTINEOPLASTIC ACTIVITY; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG STRUCTURE; INTRAPERITONEAL DRUG ADMINISTRATION; LD 50; LEUKEMIA P 388; MOUSE; MULTIDRUG RESISTANCE; NOCARDIA; NONHUMAN; PRIORITY JOURNAL;

NOCARDIA PSEUDOBRASILIENSIS;

EID: 0031845048     PISSN: 00218820     EISSN: None     Source Type: Journal    
DOI: 10.7164/antibiotics.51.589     Document Type: Article

References (7)

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2. TSUDA, M.; H. SATO, Y. TANAKA, K. YAZAWA, Y. MIKAMI, T. SASAKI & J. KOBAYASHI: Brasiliquinones A∼C, new cytotoxic benz[a]anthraquinone with an ethyl group at C-3 from actinomycete Nocardia brasiliensis. J. Chem. Soc., Perkins Trans. 1: 1773-1775, 1996
3. TANAKA, Y.; U. GRAEFE, K. YAZAWA, M. RITZAU & Y. MIKAMI: Nocardicyclins A and B: new anthracycline antibiotics produced by Nocardia pseudobrasiliensis. J. Antibiotics 50: 822-827, 1997
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6. WALLACE, R. J., Jr.; B. A. BROWN, Z. BLACKLOCK, R. ULRICH, K. JOST, J. M. BROWN, M. M MCNEIL, G. ONYI, V. A. STAINGRUBE & J. GIBSON: New Nocardia taxon among isolates of Nocardia brasiliensis associated with invasive disease. J. Clin. Microbiol. 33: 1528-1533, 1995
7. RUIMY, R.; P. RIEGEL, A. CARLOTTI, P. BOIRON, G. BERNARDIN, H. MONTEIL, R. J. WALLACE, Jr. & R. CHRISTEN: Nocardia pseudobrasiliensis sp. nov., a new species of Nocardia which groups bacterial strains previously identified as Nocardia brasiliensis and associated with invasive diseases. Int. J. Syst. Bacteriol. 46: 259-264, 1996