Alleviation of the pain of venepuncture in neonates

Acta Paediatrica, International Journal of Paediatrics

Volumn 87, Issue 7, 1998, Pages 774-779

  Larsson, B A ^a   Tannfeldt, G ^a   Lagercrantz, H ^a   Olsson, G L ^a  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Anaesthesia; Analgesia; Heel lancing; Neonates; PKU test; Topical; Venepuncture

Indexed keywords

EMLA; PLACEBO;

ANALGESIA; ARTICLE; CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; FEMALE; HAND; HUMAN; MAJOR CLINICAL STUDY; MALE; NEEDLE; NEWBORN; NOCICEPTION; PAIN; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; TOPICAL DRUG ADMINISTRATION; VEIN PUNCTURE;

ANESTHETICS, LOCAL; DOUBLE-BLIND METHOD; FEMALE; HUMANS; INFANT, NEWBORN; LIDOCAINE; MALE; OBSERVER VARIATION; PAIN; PAIN MEASUREMENT; PHLEBOTOMY; PRILOCAINE;

EID: 0031844081     PISSN: 08035253     EISSN: None     Source Type: Journal    
DOI: 10.1080/080352598750013879     Document Type: Article

References (35)

1. Larsson BA, Tannfeldt G, Lagercrantz H, Olsson GL. Venepuncture is more effective and less painful than heel-lancing for blood tests in neonates. Pediatrics (in press)
2. Hallén B, Uppfeldt A. Does lidocaine-prilocaine cream permit pain-free insertion of i.v. catheters in children? Anesthesiology 1982; 29: 453-5
3. Hallén B, Olsson GL, Uppfeldt A. Pain-free venepuncture. Effect of timing of application of local anaesthetic cream. Anesthesia 1984; 39: 969-72
4. Buckley MM, Benfield B. Eutectic lidocaine/prilocaine cream. A review of the topical anaesthetic/analgesic efficacy of an eutectic mixture of local anaesthetics (EMLA). Drugs 1993; 46: 126-51
5. Nilsson A, Engberg G, Henneberg S, Danielson K, De Verdier CH. Inverse relationship between age-dependent erythrocyte activity of methaemoglohin reductase and prilocaine-induced methaemoglobinaemia during infancy. Br J Anaesth 1990; 64: 1: 72-6
6. Jakobsson B, Nilsson A. Methaemoglobinaemia associated with a prilocaine-lidocaine cream and trimethoprim-sulphamethoxazole. A case report. Acta Anaesth Scand 1985; 29: 453-5
7. Engberg G, Danielson K, Henneberg S, Nilsson A. Plasma concentrations of prilocaine and lidocaine and methaemoglobin formation in infants after epicutaneous application of 5% lidocaine-prilocaine (EMLA). Acta Anaesth Scand 1987; 31: 7: 624-8
8. Taddio A, Shennan AT, Stevens B, Leeder JS. Safety of lidocaine-prilocaine cream in the treatment of preterm neonates. Pediatrics 1995; 127: 6: 1002-5
9. Gourrier E, Karoubi P, el Hanache A, Merbouche S, Mouchnino G, Dhabhi S, Leraillez J. Use of EMLA cream in premature and full-term newborn infants. Study of efficacy and tolerance. Arch Pediatrie 1995; 2: 11: 1041-6
10. Gourrier E, Karoubi P, el Hanache A, Merbouche S, Mouchnino G, Leraillez J. Use of EMLA cream in a department of neonatology. Pain 1996; 68: 431-4
11. Larsson BA, Jylli L, Lagercrantz H, Olsson GL. Does a local anaesthetic cream (EMLA) alleviate pain from heel-lancing in neonates? Acta Anaesth 1995; 23: 1028-31
12. Larsson BA, Norman M, Bjerring P, Egekvist H, Lagercrantz H, Olsson GL. Regional variations in skin perfusion and skin thickness may contribute to varying efficacy of topical, local anaesthetics in neonates. Pediatr Anaesth 1996; 6: 107-10
13. Grunau RVE, Craig KD. Pain expression in neonates: Facial reaction and cry. Pain 1987; 28: 395-410
14. Ekman P, Friesen WV. Manual for the facial coding system. Palo Alto, CA: Consulting Psychologist's Press, 1978
15. Grunau RVE, Johnston CC, Craig KD. Neonatal facial and cry responses to invasive and non-invasive procedures. Pain 1990; 42: 295-305
16. Bjerring P, Arendt-Nielsen L. Depth and duration of skin analgesia to needle insertion after topical application of EMLA cream. Br J Anaesth 1990; 64: 173-7
17. Kurien L, Kollberg H, Uppfeldt A. Venepuncture pain can be reduced. J Trop Med Hyg 1985; 88: 397-9
18. Bjerring P, Andersen PH, Arendt-Nielsen L. Vascular response of human skin after analgesia with EMLA cream. Br J Anaesth 1989; 63: 655-60
19. Amdisen A, Glud V. No influence from topical application of EMLA cream before blood sampling on routine chemistry and haematology measurements. Eur J Clin Pharmacol 1991; 41: 619-20
20. Lorey FW, Cunningham GC. Effect of specimen collection method on newborn screening for PKU. Screening 1994; 3: 57-65
21. Owens ME, Todt EH. Pain in infancy: Neonatal reaction to a heel lance. Pain 1984; 20: 77-86
22. Rushforth JA, Levene MI. Behavioural response to pain in healthy neonates. Arch Dis Child 1994; 70: F174-6
23. Brown L. Physiologic responses to cutaneuous pain in neonates. Neonatal Network. 1987; 6: 18-22
24. McIntosh N, Veen L, Brameyer H. Alleviation of the pain of heel prick in preterm infants. Arch Dis Child 1994; 70: F177-F181
25. Smith BA, Fillion TJ, Blass EM. Orally-mediated sources of calming in one-to three-day-old human infants. Develop Psychol 1990; 26: 731-7
26. Blass EM, Fitzgerald, Kehoe P. Interactions between sucrose, pain and isolation distress. Pharmacol Biochem Behav 1987; 26: 483-9
27. Ramenghi LA, Griffith GC, Wood CM, Levene MI. Effect of non-sucrose sweet tasting solution on neonatal heel prick responses. Arch Dis Childhood 1996; 74: F129-31
28. Gunnar MR, Fish RO, Malone S. The effect of a pacifying stimulus on behavior and adrenocortical response to circumcision in the newborn. J Am Acad Child Psychiatr 1984; 23: 34-8
29. Johnston CC, Stremler RL, Stevens BJ, Horton LJ. Effectiveness of oral sucrose and simulated rocking on pain response in preterm neonates. Pain 1997; 72: 193-9
30. Barker DP, Rutter N. Exposure to invasive procedures in neonatal intensive care unit admissions. Arch Dis Child. Fetal & Neonatal Edition. 1995; 72: F47-8
31. Anand KJS, Phil D, Hickey PR. Pain and its effects in the human neonate and fetus. New Engl. J Med 1987; 317: 1321-9
32. Anand KJS. Long term effects of pain in neonates and infants. 8th world Congress of Pain. August 1996. Vancouver, Canada. IASP Press, 1996
33. Taddio A, Katz J Ilersich AL, Koren G. Effect of neonatal circumcision on pain response during subsequent routine vaccination. Lancet 1997; 349: 599-603
34. Fitzgerald M, Millard C, McIntosh N. Cutaneous hypersensitivity following peripheral tissue damage in newborn infants and its reversal with topical anesthesia. Pain 1989; 39: 31-6
35. Benini F, Johnston CC, Faucher D, Aranda JV. Topical anesthesia during circumcision in newborn infants. JAMA 1993; 270: 7: 850-3