Assessment of D-glucose transport kinetics in the perfused human placenta: An in vitro study

Pediatrics International

Volumn 40, Issue 4, 1998, Pages 307-312

  Nandakumaran, Moorkath ^a   Dev, Bhaskar R ^a   Makhseed, Ma'Asoumah ^a   Sugathan, Thattaruparambil N ^a  

^a KUWAIT UNIVERSITY   (Kuwait)

Author keywords

D glucose; Human placenta; Maternal fetal exchange; Perfusion; Transport kinetics; Tritiated water

Indexed keywords

CARBON 14; GLUCOSE; TRITIUM OXIDE;

AREA UNDER THE CURVE; ARTICLE; CLEARANCE; CONTROLLED STUDY; FEMALE; FETOMATERNAL TRANSFUSION; FETUS CIRCULATION; GLUCOSE ABSORPTION; GLUCOSE TRANSPORT; HUMAN; HUMAN TISSUE; HYPERGLYCEMIA; PLACENTA; PRIORITY JOURNAL; TRANSPORT KINETICS; WATER TRANSPORT;

FEMALE; GLUCOSE; HUMANS; MATERNAL-FETAL EXCHANGE; PLACENTA; PREGNANCY;

EID: 0031844039     PISSN: 13288067     EISSN: 1442200X     Source Type: Journal    
DOI: 10.1111/j.1442-200X.1998.tb01937.x     Document Type: Article

References (29)

1. Salafia C. The fetal, placental and neonatal pathology associated with maternal diabetes mellitus. In: Reece Ea, Coustan Dr (eds). Diabetes mellitus in pregnancy. Principles and practice. New York, Churchill Livingstone, 1988; 143–81.
2. Yudilevich Dl, Eaton Bm, Short Ah, Leichtweiss Hp. Glucose carriers at maternal and fetal sides of the trophoblast in guinea pig placenta. Am. J. Physiol. 1979; 237: C205–12.
3. Bissonnette Jm. Studies in vivo of glucose transfer across the guinea pig placenta. Placenta 1981; 2 (Suppl.): 155–62.
4. Simmons Ma, Battaglia Fc, Meschia G. Placental transfer of glucose. J. Dev. Physiol. 1979; 1: 227–43.
5. Thomas Cr, Lowy C. Bidirectional placental transfer (‘leak’) of L-glucose in control and diabetic rats. Acta Diabetol. 1995; 32: 23–7.
6. Chinard S., Danesino V., Hartman Wf, Huggett Asg, Paul W., Reynolds Srm. The transmission of hexoses across the placenta in the human and rhesus monkey. J. Physiol. 1956; 132: 289–92.
7. Nesbitt Rel, Rice Pa, Rourke Je. In vitro perfusion studies of the human placenta. III. The relationship between glucose utilization rates and concentrations. Gynecol. Invest. 1973; 4: 243–53.
8. Carlstensen M., Leichtweiss Hp, Molsen G., Schroder H. Evidence for a specific transport of D-hexoses across the human term placenta in vitro. Arch. Gynak. 1977; 222: 197–8.
9. Challier Jc, Nandakumaran M., Mondon F. Placental transport of hexoses: A comparative study with antipyrine and amino acids. Placenta 1985; 6: 497–504.
10. Smith Ch, Nelson Dm, King Bf, Donohue Tm, Ruzycki Sm, Kelley Lk. Characterization of a microvillous membrane preparation from human placental syncytiotrophoblast: a morphologic, biochemical and physiologic study. Am. J. Obstet. Gynecol. 1977; 128: 190–6.
11. Johnson Lw, Smith Ch. Glucose transport across the basal plasma membrane of human syncytiotrophoblast. Biochim. Biophys. Acta 1985; 815: 544–50.
12. Hauguel S., Desmaizieres V., Challier Jc. Glucose uptake, utilization and transfer by the human placenta as functions of maternal glucose concentration. Pediatr. Res. 1986; 20: 269–73.
13. Nandakumaran M., Makhseed M., Devarajan Lv. Transport of water and insulin in insulin-dependent diabetic pregnancies: In vitro study. Diabetes Res. 1995; 28: 9–15.
14. Nandakumaran M., Makhseed M. Placental transport kinetics of alpha-aminoisobutyric acid (AIB) in vitro in insulin-dependent diabetic pregnancies. Diabetes Res. 1995; 29: 93–102.
15. Panigel M., Pascaud M., Brun Jl. Une nouvelle technique de perfusion de l'espace intervilleux dans le placenta humain isole. Pathol. Biol. 1967; 15: 821.
16. Nandakumaran M., Gardey C., Challier Jc, Richard Mo, Panigel M., Olive G. Transfer of salbutamol. in the human placenta in vitro. Dev. Pharmacol. Then 1981; 3: 88–98.
17. Nandakumaran M., Challier Jc, Rey E., Richard Mo, Olive G. In vitro transfer of six benzamides in the human placenta. Dev. Pharmacol. Ther. 1984; 7: 60–6.
18. Schneider H. Proegler M, Sodha R, Dancis J. Asymmetrical transfer of alpha-aminoisobutyric acid (AIB), leucine and lysine across the in vitro perfused human placenta. Placenta 8: 141–51.
19. Nandakumaran M., Sugathan Tn. Assessment of transport dynamics in the perfused human placental lobule; In vitro study. Med. Principles Pract. 1992-3; 3: 219–22.
20. Hay Ww Jr, Sparks Jw, Wlikening Rb, Battaglia Fc, Meschia G. Fetal glucose uptake and utilization as functions of maternal glucose concentration. Am. J. Physiol. 1984; 246: E237–42.
21. Crandell Ss, Fisher Dj, Morriss Fh. Effects of ovine maternal hyperglycemia on fetal regional blood flows and metabolism. Am. J. Physiol. 1985; 249: E454–60.
22. Herrera E., Palacin M., Martin A., Lasuncion Ma. Relationship between maternal and fetal fuels and placental glucose transfer in rats with maternal diabetes of varying severity. Diabetes 1985: 34: 42–6.
23. Rice Pa, Rourke Je, Nesbitt Rel. In vitro perfusion studies of the human placenta. IV. Some characteristics of the glucose transport system in the human placenta. Gynecol. Invest. 1976; 213–21.
24. Schneider H., Challier Jc, Dancis J. Transfer and metabolism of glucose and lactate in the human placenta studied by a perfusion system in vitro. Placenta 1981; 2 (Suppl.): 129–35.
25. Bell Gi, Kayono T., Buse Jb, Molecular biology of mammalian glucose transporters. Diabetes Care 1990; 13: 198–208.
26. Devaskar Su, Mueckler Mm. The mammalian glucose transporters. Pediatr. Res. 1992; 31: 1–13.
27. Jansson T., Wennergren M., Illsley Np. Glucose transporter protein expression in human placenta throughout gestation and in intrauterine growth retardation. J. Clin. Endocrinol. Metab. 1993; 77: 1554–62.
28. Morris Fh, Boyd Rdh, Mahendran D. Placental transport. In. Knobil E., Neill Jd (eds). The Physiology of Reproduction. New York, Raven Press, 1994; 813–61.
29. Reece Ea, Pinter E., Homko C., Wu Yk, Nafrolin F. The yolksac theory: Closing the circle on why diabetes-associated malformations occur. J. Soc. Gynecol. Invest. 1994; 1: 3–13.