Small-cell lung carcinoma: An analysis of 194 consecutive patients

American Journal of Clinical Oncology: Cancer Clinical Trials

Volumn 21, Issue 4, 1998, Pages 333-337

  Dosoretz, Daniel E ^a,b,c,d,e   Rubenstein, James H ^a,b,c,d,e   Katin, Michael J ^a,b,c,d,e   Blitzer, Peter H ^a,b,c,d,e   Reisinger, Susan A ^a,b,c,d   Garton, Graciela R ^a,b,c,d   Salenius, Sharon A ^a,b,c,d   Harwin, William H ^h   Teufel, Thomas E ^h   Raymond, Michael G ^f   Reeves, James A ^h   Rubin, Mark S ^h   Hart, Lowell L ^h   McCleod, Michael J ^f   Pizarro, Alejandro ^g   Gabarda, Antonio L ^g  

^a Radiation Therapy Regional Center   (United States)

^b Radiation Therapy Regional Centers   (United States)

^c Radiation Therapy Regional Center   (United States)

^d Radiation Therapy Regional Centers   (United States)

^e UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^f Island Coast Hematology and Oncology   (United States)

^g Intermedic Health Center   (United States)

^h NONE

Author keywords

Carcinoma, small cell; Chemotherapy; Combined modality therapy; Lung neoplasms; Radiotherapy

Indexed keywords

ANTINEOPLASTIC AGENT; CISPLATIN; CYCLOPHOSPHAMIDE; DOXORUBICIN; ETOPOSIDE; VINCRISTINE;

ADULT; AGED; ARTICLE; CANCER COMBINATION CHEMOTHERAPY; CANCER RADIOTHERAPY; CANCER SURVIVAL; CONTROLLED STUDY; FEMALE; HUMAN; LUNG FIBROSIS; LUNG SMALL CELL CANCER; MAJOR CLINICAL STUDY; MALE; MULTIMODALITY CANCER THERAPY; NAUSEA; NEUTROPENIA; PROGNOSIS; SURVIVAL TIME; TREATMENT OUTCOME; VOMITING;

ADULT; AGED; AGED, 80 AND OVER; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; CARCINOMA, SMALL CELL; COMBINED MODALITY THERAPY; CRANIAL IRRADIATION; FEMALE; HUMANS; LUNG NEOPLASMS; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; SURVIVAL ANALYSIS;

EID: 0031843912     PISSN: 02773732     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000421-199808000-00003     Document Type: Article

References (14)

1. Rubenstein JH, Dosoretz DE, Katin MJ, et al. Low doses of prophylactic cranial irradiation effective in limited stage small cell carcinoma of the lung. Int J Radiat Oncol Biol Phys 1995;33:329-37.
2. Murray N, Coy P, Pater JL, et al. Importance of timing for thoracic irradiation in the combined modality treatment of limited-stage small-cell lung cancer. J Clin Oncol 1993;11:336-44.
3. Coy P, Hodson I, Murray N, et al. Patterns of failure following loco-regional radiotherapy in the treatment of limited stage small cell lung cancer. Int J Radiat Oncol Biol Phys 1994;28:355-62.
4. Komaki R, Shin DM, Glisson BS, et al. Interdigitating versus concurrent chemotherapy and radiotherapy for limited small cell lung cancer. Int J Radiat Oncol Biol Phys 1995;31:801-11.
5. Pignon J-P, Arriagada R, Ihde DC, et al. A meta-analysis of thoracic radiotherapy for small-cell lung cancer. N Engl J Med 1992;327:1618-24.
6. Lichter AS, Bunn Jr PA, Ihde DC, et al. The role of radiation therapy in the treatment of small cell lung cancer. Cancer 1985;55:2163-75.
7. Turrisi AT. Platinum combined with radiation therapy in small cell lung cancer: focusing like a laser beam on crucial issues. Semin Oncol 1994;21:36-42.
8. Perez CA, Stanley K, Grundy G, et al. Impact of irradiation technique and tumor extent in tumor control and survival of patients with unresectable non-oat cell carcinoma of the lung. Report by the Radiation Therapy Oncology Group. Cancer 1982;50:1091-9.
9. Mira JG, Livingston RB, Moore TN, et al. Influence of chest radiotherapy in frequency and patterns of chest relapse in disseminated small cell lung carcinoma. A Southwest Oncology Group Study. Cancer 1982;50:1266-72.
10. Liengswangwong V, Bonner JA, Shaw EG, et al. Limited-stage small-cell lung cancer: patterns of intrathoracic recurrence and the implications for thoracic radiotherapy. J Clin Oncol 1994;12:496-502.
11. Kies MS, Mira JG, Crowley JJ, et al. Multimodal therapy for limited small-cell lung cancer: a randomized study of induction combination chemotherapy with or without thoracic radiation in complete responders, and with wide-field versus reduced-field radiation in partial responders: a Southwest Oncology Group study. J Clin Oncol 1987;5:592-600.
12. Arriagada R, Le Chevalier T, Pignon J-P, et al. Initial chemotherapeutic doses and survival in patients with limited small-cell lung cancer. N Engl J Med 1993;329:1848-52.
13. Turrisi AT, Glover DJ. Thoracic radiotherapy variables: influence on local control in small cell lung cancer limited disease. Int J Radiat Oncol Biol Phys 1990;19:1473-9.
14. Goldie JG, Coldman AJ. A mathematic model for relating the drug sensitivity of tumors to their spontaneous mutation rate. Cancer Treatment Reports 1979;63:1727-33.