Changes in the lipoprotein profile in postmenopausal women receiving hormone replacement therapy: Effects of natural and synthetic progesterone

Journal of Reproductive Medicine for the Obstetrician and Gynecologist

Volumn 43, Issue 7, 1998, Pages 568-574

  Chen, Fang Ping ^a   Lee, Ning ^a   Soong, Yung Kui ^a  

^a CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

Author keywords

Hormone replacement therapy; Lipoproteins; Menopause; Post menopausal; Progesterone

Indexed keywords

CONJUGATED ESTROGEN; HIGH DENSITY LIPOPROTEIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL; MEDROXYPROGESTERONE ACETATE; PROGESTERONE;

ADULT; AGED; ARTICLE; CHOLESTEROL BLOOD LEVEL; CORONARY RISK; DRUG EFFECT; ESTROGEN THERAPY; FEMALE; HEART PROTECTION; HORMONE SUBSTITUTION; HUMAN; ISCHEMIC HEART DISEASE; LIPID METABOLISM; LIPOPROTEIN BLOOD LEVEL; LIPOPROTEIN METABOLISM; MAJOR CLINICAL STUDY; POSTMENOPAUSE; PRIORITY JOURNAL; RISK FACTOR;

ADULT; CARDIOVASCULAR DISEASES; ESTROGEN REPLACEMENT THERAPY; FEMALE; HUMANS; LIPOPROTEINS; MEDROXYPROGESTERONE 17-ACETATE; MIDDLE AGED; POSTMENOPAUSE; PROGESTERONE; PROGESTERONE CONGENERS; PROSPECTIVE STUDIES;

EID: 0031843855     PISSN: 00247758     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (40)

1. Martin MJ, Hulley SB, Browner WS, et al: Serum cholesterol, blood pressure, and mortality: Implications from a cohort of 361,662 men. Lancet 1986;2:933-936
2. Stamler J, Wentworth D, Neaton JD: Is the relationship between serum cholesterol and risk of premature death from coronary heart disease continuous and graded? JAMA 1986; 256:2823-2828
3. Castelli WP, Garrison PJ, Wilson PWF, et al: Incidence of coronary heart disease and lipoprotein cholesterol levels: The Framingham Study. JAMA 1986;256:2835-2838
4. Ross RK, Paganini-Hill A, Mack TH, et al: Cardiovascular benefits of estrogen replacement therapy. Am J Obstet Gynecol 1989;160:1301-1306
5. Colditz GA, Willett WC, Stampfer MJ, et al: Menopause and the risk of coronary heart disease in women. N Engl J Med 1987;316:1105-1110
6. Bush TL, Barrert-Connor E, Cowan LD, et al: Cardiovascular mortality and noncontraceptive use of estrogen in women: Results from the lipid research clinics program follow-up study. Circulation 1987;75:1102-1109
7. Sullivan JM, Zwaag RV, Lemp GF, et al: Postmenopausal estrogen use and coronary atherosclerosis. Ann Intern Med 1988;108:358-363
8. Witteman JCM, Grobbee DE, Kok FJ, et al: Increased risk of atherosclerosis in women after menopause. Br Med J 1989; 298:642-644
9. Stampfer MJ, Colditz GA, Willett WC, et al: Postmenopausal estrogen therapy and cardiovascular disease. N Engl J Med 1991;325:756-762
10. Knopp RH: The effect of postmenopausal estrogen therapy on the incidence of arteriosclerotic vascular disease. Obstet Gynecol 1988;72:23S-30S
11. Lobo RA: Effects of hormone replacement on lipids and lipoproteins in postmenopausal women. J Clin Endocrinol Metab 1991;73:925-930
12. Walsh BW, Schiff I, Rosner B, et al: Effects of postmenopausal estrogen replacement therapy on the concentrations and metabolism of plasma lipoproteins. N Engl J Med 1991; 325:1196-1204
13. Williams KJ, Adams MR, Klopfenstein SH: Estrogen modulates responses of atherosclerotic coronary arteries. Circulation 1990;81:1680-1687
14. Negre-Salvayre A, Pieraggi M, Mabile M, et al: Protective effect of 17β-estradiol against the cytotoxicity of minimally oxidized LDL to cultured bovine aortic endothelial cells. Atherosclerosis 1993;99:207-217
15. Smith DC, Prentice R, Thompson DJ, et al: Association of exogenous estrogen and endometrial carcinoma. N Engl J Med 1975;293:1164-1167
16. Whitehead MI, King RJB, McQueen J, et al: Endometrial histology and biochemistry in climacteric women during oestrogen and oestrogen/progestogen therapy. J R Soc Med 1979;72:322-327
17. Hulka BS, Kaufman DG, Fowler WC, et al: Predominance of early endometrial cancers after long-term estrogen use. JAMA 1980;244:2419-2422
18. Gambrell RD Jr: The menopause: Benefits and risks of estrogen-progestogen replacement therapy. Fertil Steril 1982;37:457-474
19. Sherwin BB, Gelfand MM: A prospective one-year study of estrogen and progestin in postmenopausal women: Effects on clinical symptoms and lipoprotein lipids. Obstet Gynecol 1989;73:759-766
20. Crook D, Stevenson JC: Progestogens, lipid metabolism and hormone replacement therapy. Br J Obstet Gynaecol 1991;98: 749-750
21. Yancey MK, Hannan CJ, Plymate SR, et al: Serum lipids and lipoproteins in continuous or cyclic medroxyprogesterone acetate treatment in postmenopausal women treated with conjugated estrogens. Fertil Steril 1990;54:778-782
22. Haarbo J, Hassager C, Jensen SB, et al: Serum lipids, lipoproteins and apolipoproteins during postmenopausal estrogen replacement therapy combined with either 19-Nortestosterone derivatives or 17-hydroxy progesterone derivatives. Am J Med 1991;90:584-589
23. Jensen J, Riis BJ, Strom V, et al: Long-term effects of percutaneous estrogens and oral progesterone on serum lipoproteins in postmenopausal women. Am J Obstet Gynecol 1987; 156:66-71
24. Ottosson UB, Johansson BG, von Schoultz B: Subfractions of high-density lipoprotein cholesterol during estrogen replacement therapy: A comparison between progestogens and natural progesterone. Am J Obstet Gynecol 1985;151: 746-750
25. Campos H, McNamara JR, Wilson PW, et al: Differences in low density lipoprotein subfractions and apolipoproteins in premenopausal and postmenopausal women. J Clin Endocrinol Metab 1988;67:30-35
26. Mathews KA, Meilhan E, Kuller LH, et al: Menopause and risk factors for coronary heart disease. N Engl J Med 1989; 321:641-646
27. Kim CJ, Min YK, Ryu WS, et al: Effect of hormone replacement therapy on lipoprotein (a) and lipid levels in postmenopausal women. Arch Intern Med 1996;156:1693-1700
28. Jensen J, Nilas L, Christiansen C: Cyclic changes in serum cholesterol and lipoproteins following different doses of combined postmenopausal hormone replacement therapy. Br J Obstet Gynaecol 1986;93:613-618
29. Gambrell RD JR, Teran A-Z: Changes in lipids and lipoproteins with long-term estrogen deficiency and hormone replacement therapy. Am J Obstet Gynecol 1991;165:307-317
30. The Writing Group for the PEPI Trial: Effects of estrogen or estrogen/ progestin regimens on heart disease risk factors in postmenopausal women. JAMA 1995;273:199-208
31. Paganini-Hill A, Dworsky R, Krauss RM: Hormone replacement therapy, hormone levels, and lipoprotein cholesterol concentrations in elderly women. Am J Obstet Gynecol 1996; 174:897-902
32. Rijpkema AHM, Van der Sanden AA, Ruijs AHC: Effects of postmenopausal oestrogen-progesterone replacement therapy on serum lipids and lipoproteins: A review. Maturitas 1990;12:259-285
33. Crook D, Cust MP, Gangar KF, et al: Comparison of transdermal and oral estrogen-progestin replacement therapy: Effects on serum lipids and lipoproteins. Am J Obstet Gynecol 1992;166:950-955
34. Miller VT, Muesing RA, LaRosa JC, et al: Effects of conjugated equine estrogen with and without three different progestogens on lipoproteins, high-density lipoprotein subfractions, and apolipoprotein A-I. Obstet Gynecol 1991;77: 235-240
35. Nabulsi AM, Folsom AR, White A, et al: Association of hormone-replacement therapy with various cardiovascular risk factors in postmenopausal women. N Engl J Med 1993;328: 1069-1075
36. Barrett-Connor E, Wingard D, Criqui MH: Postmenopausal estrogen use and heart disease risk factors in the 1980s. JAMA 1989;261:2095-2100
37. Farish E, Fletcher CD, Hart DM, et al: The effects of conjugated equine oestrogens with and without a cyclical progestogen on lipoproteins, and HDL subfractions in postmenopausal women. Acta Endocrinol 1986;113:123-127
38. Weinstein L: Efficacy of a continuous estrogen-progestin regimen in the menopausal patient. Obstet Gynecol 1987;69: 929-932
39. Kannel WB: Metabolic risk factors for coronary artery disease in women: Perspective from the Framingham study. Am Heart J 1987;114:413-419
40. Whitehead MI, Fraser D: The effects of estrogens and progestogens on the endometrium. Obstet Gynecol Clin North Am 1987;14:299-320