Transforming growth factor β2 in the vitreous in proliferative diabetic retinopathy

Archives of Ophthalmology

Volumn 116, Issue 6, 1998, Pages 738-741

  Hirase, Kumiko ^a   Ikeda, Tsunehiko ^a   Sotozono, Chie ^a   Nishida, Kohji ^a   Sawa, Hiroshi ^a   Kinoshita, Shigeru ^a  

^a KYOTO PREFECTURAL UNIVERSITY OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

TRANSFORMING GROWTH FACTOR BETA2;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DIABETIC RETINOPATHY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMAN; HUMAN TISSUE; LASER COAGULATION; MALE; PRIORITY JOURNAL; VITRECTOMY; VITREOUS BODY;

EID: 0031842676     PISSN: 00039950     EISSN: None     Source Type: Journal    
DOI: 10.1001/archopht.116.6.738     Document Type: Article

References (23)

1. Forrester JV, Shafiee A, Schröder S, Knott R, McIntosh L. The role of growth factors in proliferative diabetic retinopathy. Eye. 1993;7:276-287.
2. Wiedemann P. Growth factors in retinal diseases. Sun Ophthalmol. 1992;36: 373-384.
3. Sebag J. McMeel JW. Diabetic retinopathy. Sun Ophthalmol. 1986;30:377-384.
4. Sivalingam A, Kenney J, Brown GC, Benson WE, Donoso L. Basic fibroblast growth factor levels in the vitreous of patients with proliferative diabetic retinopathy. Arch Ophthalmol. 1990;108:869-872.
5. Grant M, Russell B, Fitzgerald C, Merimee TJ. Insulin-like growth factors in vitreous. Diabetes. 1986;35:416-420.
6. Aiello LP, Avery RL, Arrigg PG, et al. Vascular endothelial growth factor in ocular fluid of patients with diabetic retinopathy and other retinal disorders. N Engl J Med. 1994;331:1480-1487.
7. Adamis AP, Miller JW, Bernal MT, et al. Increased vascular endothelial growth factor levels in the vitreous of eyes with proliferative diabetic retinopathy. Am J Ophthalmol. 1994;118.445-450.
8. Sporn MB, Roberts AB, Wakefield LM, de Crombrugghe B. Some recent advances in the chemistry and biology of transforming growth factor-beta. J Cell Biol. 1987;105:1039-1045.
9. Roberts AB, Anzano MA, Wakefield LM, et al. Type β transforming growth factor: a bifunctional regulator of cellular growth. Proc Natl Acad Sci U S A. 1985;82:119-123.
10. Sporn MB, Roberts AB, Wakefield LM, Assoian RK. Transforming growth factor- β: biological function and chemical structure. Science. 1986;233:532-534.
11. Sporn MB, Roberts AB. Peptide growth factors are multifunctional. Nature. 1988; 332:217-219.
12. Brown PD, Wakefield LM, Levinson AD, Sporn MB. Physicochemical activation of recombinant latent transforming growth factor-beta's 1.2, and 3. Growth Factors 1990;3:35-43.
13. β3 in the anterior segment of the human eye. Invest Opthalmol Vis Sci. 1993;34:23-30.
14. Lutty GA, Merges C, Threlkeld AB, Crone S, McLeod DS. Heterogeneity in localization of isoforms of TGF- β in human retina, vitreous, and choroid. Invest Ophthalmol Vis Sci. 1993;34:477-487.
15. Tanihara H, Yoshida M, Matsumoto M, Yoshimura N. Identification of transforming growth factor- β expressed in cultured human retinal pigment epithelial cells. Invest Ophthalmol Vis Sci. 1993;34:413-419.
16. Lutty G, Ikeda K, Chandler C, McLeod DS. Immunohistochemical localization of transforming growth factor- β in human photoreceptors. Cutr Eye Res. 1991;10:61-74.
17. 2 is the predominant isoform in the neural retina, retinal pigment epithelium-choroid and vitreous of the monkey eye. Exp Eye Res 1994;59:323-333.
18. Connor TB, Roberts AB, Sporn MB, et al. Correlation of fibrosis and transforming growth factor- β type 2 levels in the eye J Clin Invest. 1989;83:1661-1666.
19. β2 in aqueous humor during uveitis. Invest Ophthalmol Vis Sci. 1994;35:3702-3710.
20. 2 levels increase following retinal laser photocoagulation. Curr Eye Res. 1994;13:743-746.
21. 2 from cultured human retinal pigment epithelial cells by photocoapulation. Invest Ophthalmol Vis Sci. 1994;35:4245-4252.
22. Yoshimura N, Matsumoto M, Shimizu H, et al. Photocoagulated human retinal pigment epithelial cells produce an inhibitor of vascular endothelial cell proliferation. Invest Ophthalmol Vis Sci. 1995:36:1686-1691.
23. Boulton M, Gregor Z, McLeod D, et al. Intravitreal growth factors in proliferative diabetic retinopathy. Br J Ophthalmol. 1997;81:228-233.