Synaptically evoked dendritic action potentials in rat neocorfical pyramidal neurons

Journal of Neurophysiology

Volumn 79, Issue 5, 1998, Pages 2432-2446

  Schwindt, Peter C ^a   Crill, Wayne E ^a  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUTAMATE RECEPTOR;

ACTION POTENTIAL; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; ELECTROSTIMULATION; EXCITATORY POSTSYNAPTIC POTENTIAL; IONTOPHORESIS; MICROELECTRODE; NEOCORTEX; NONHUMAN; PRIORITY JOURNAL; PYRAMIDAL NERVE CELL; RAT;

EID: 0031841079     PISSN: 00223077     EISSN: None     Source Type: Journal    
DOI: 10.1152/jn.1998.79.5.2432     Document Type: Article

References (19)

1. ANDERSEN, P., STORM, J., AND WHEAL, H. V. Thresholds of action potentials evoked by synapses on the dendrites of pyramidal cells in the rat hippocampus in vitro. J. Physiol (Lond.) 383: 509-526, 1987.
2. CAULLER, L. J. AND CONNORS, B. W. Functions of very distal dendrites: experimental and computational studies of layer I synapses on neocortical pyramidal cells. In: Single Neuron Computation, edited by T. McKenna, J. Davis, and S. F. Zornetzer. New York: Academic, 1992, p. 199-230.
3. CAULLER, L. J. AND CONNORS, B. W. Synaptic physiology of horizontal afferents to layer I in slices of rat SI neocortex. J. Neurosci. 14: 751-762, 1994.
4. COLLING, S. B. AND WHEAL, H. V. Fast sodium action potentials are generated in the distal apical dendrites of rat hippocampal CA1 pyramidal cells. Neurosci. Lett. 172: 73-76, 1994.
5. HUFFMAN, D. A., MAGEE, J. C., COLBERT, C. M., AND JOHNSTON, D. K channels regulation of signal propagation in dendrites of hippocampal pyramidal neurons. Nature 387: 869-875, 1997.
6. KIM, H. G. AND CONNORS, B. W. Apical dendrites of the neocortex: correlation between sodium-and calcium-dependent spiking and pyramidal cell morphology. J. Neurosci. 13: 5301-5311, 1993.
7. 2+ influx into the dendrites of hippocampal pyramidal neurons. J. Neurophysiol. 74: 1335-1342, 1995.
8. MARKRAM, H. AND SAKMANN, B. Calcium transients in dendrites of neocortical neurons evoked by single subthreshold excitatory postsynaptic potentials via low-voltage-activated calcium channels. Proc. Natl. Acad. Sci. USA 91: 5207-5211, 1994.
9. POOLOS, N. P. AND KOCSIS, J. D. Dendritic action potentials activated by NMDA receptor-mediated EPSPs in CA1 hippocampal pyramidal cells. Brain Res. 524: 342-346, 1990.
10. REGEHR, W. G., KEHOW, J., ASCHER, P, AND ARMSTRONG, C. Synaptically triggered action potentials in dendrites. Neuron 11: 145-151, 1993.
11. SCHILLER, J., SCHILLER, Y., AND SAKMANN, B. Calcium action potentials in apical dendrite of neocortical pyramidal neurons in rat brain slices Soc. Neurosci. Abstr. 22: 794, 1996.
12. SCHWINDT, P. C. AND CRILL, W. E. Amplification of synaptic current by persistent sodium conductance in apical dendrite of neocortical neurons. J. Neurophysiol. 74: 2220-2224, 1995.
13. SCHWINDT, P. C. AND CRILL, W. E. Equivalence of amplified current flowing from dendrite to soma measured by alteration of repetitive firing and by voltage clamp in layer 5 pyramidal neurons. J. Neurophysiol. 76: 3731-3739, 1996.
14. SCHWINDT, P. C. AND CRILL, W. E. Local and propagated dendritic action potentials evoked by glutamate iontophoresis on rat neocortical pyramidal neurons. J. Neurophysiol. 77: 2466-2483, 1997.
15. SCHWINDT, P. C., O'BRIEN, J. A., AND CRILL, W. E. Quantitative analysis of firing properties of pyramidal neurons from layer 5 of rat sensorimotor cortex. J. Neurophysiol. 77: 2484-2498, 1997.
16. STUART, G. AND SAKMANN, B. Action potential initiation in neocortical neurons-revisited. Soc. Neurosci. Abstr. 22: 794, 1996.
17. STUART, G., SPRUSTON, N., SAKMANN, B., AND HAEUSSER, M. Action potential initiation and backpropagation in neurons of the mammalian CNS. Trends Neurosci. 20: 125-131, 1997.
18. TURNER, R. W., MEYERS, D.E.R., RICHARDSON, T. L., AND BARKER, J. L. The site for initiation of action potential discharge over the somatodendritic axis of rat hippocampal CA1 pyramidal neurons. J. Neurosci. 11: 2270-2280, 1991.
19. ZILLES, K. AND WREE, A. Cortex area 1 and laminar structure. In: The Rat Nervous System, edited by G. Paxinos. Sydney, Australia: Academic, 1985, vol. 1, p. 375-415.