Preparation and evaluation of micro-porous ethylcellulose capsule as oral sustained-release preparation of theophyllin

Biopharmaceutics and Drug Disposition

Volumn 19, Issue 5, 1998, Pages 333-339

  Yoshikawa, Y ^a   Kawai, A ^a   Yasui, H ^a   Yoshikawa, H ^b   Takada, K ^a  

^a KYOTO PHARMACEUTICAL UNIVERSITY   (Japan)

^b UNIVERSITY OF TOYAMA   (Japan)

Author keywords

Beagle dog; EC capsule; Micro porous membrane; Sustained release; Theophylline

Indexed keywords

ETHYL CELLULOSE; THEOPHYLLINE;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; DOG; DRUG MIXTURE; DRUG SOLUBILITY; FOOD DRUG INTERACTION; MALE; NONHUMAN; ORAL DRUG ADMINISTRATION; SUSTAINED RELEASE PREPARATION;

ADMINISTRATION, ORAL; ANIMALS; CAPSULES; CELLULOSE; DELAYED-ACTION PREPARATIONS; DOGS; FOOD; MALE; SOLUBILITY; THEOPHYLLINE;

EID: 0031839596     PISSN: 01422782     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1099-081X(199807)19:5<333::AID-BDD109>3.0.CO;2-L     Document Type: Article

References (20)

1. J.G. Hardy, S.S. Davis and C.G. Wilson (Ed.), Drug Delivery to the Gastrointestinal Tract, Ellis Horwood, Chichester, UK, 1989.
2. T. Takaya, C. Ikeda, N. Imagawa, K. Niwa and K. Takada, Development of a colon delivery capsule and the pharmacological activity of recombinant human granulocyte colony-stimulating factor (rhG-CSF) n beagle dogs, J. Pharm. Pharmacol., 47, 474-478 (1995).
3. K. Niwa, T. Takaya, T. Morimoto and K. Takada, Preparation and evaluation of a time-controlled release capsule made of EC for colon delivery of drugs. J. Drug Targeting, 3, 83-89 (1995).
4. T. Houjou, K. Nakano, O. Ike, H. Wada, S. Hitomi, Y. Shinmi, N. Danno, Y. Yoshikawa and K. Takada, Oral sustained-release cisplatin capsule. J. Pharm. Pharmacol., 48, 474-478 (1996).
5. R.F. Adams, F.L. Vandemark and G.J. Schmidt, More sensitive high-pressure liquid-chromatographic determination of theophylline in serum. Clin. Chem., 22, 1903-1906 (1976).
6. M. Gibaldi and D. Perrier, Pharmacokinetics, 2nd edn., Marcel Dekker, New York, 1982.
7. M. Weingerber and E. Bronsky, Evaluation of oral bronchodilator therapy in asthmatic children, J. Pediatr., 84, 421-427 (1974).
8. J.G. Hardy, S.S. Davis and C.G. Wilson, Drug Delivery to the Gastrointestinal Tract, Ellis Horwood, Chichester, UK, 1989.
9. G.K. Shiu, A. LeMarchand, A.O. Sager, R.B. Velagapudi and J.P. Skelly, The beagle dog as an animal model for a bioavailability study of controlled-release theophylline under the influence of food. Pharmaceut. Res., 6, 1039-1042 (1989).
10. K. Matsuda, T. Takaya, F. Shimoji, M. Muraoka, Y. Yoshikawa and K. Takada, Effect of food intake on the delivery of fluorescein as a model drug in colon delivery capsule after oral administration to beagle dogs, J. Drug Targeting, 4, 59-67 (1996).
11. C.S. Cook, C.L. Hauwald, A.Y. Grahn, K. Kowalski, A. Karm, R. Koch, G.L. Schoenhard and J.A. Oppermann, Suitability of the dog as an animal model for evaluating theophylline absorption and food effects from different formulations. Int. J. Pharm., 60, 125-132 (1990).
12. H. Mizuta, Y. Kawazoe, K. Haga, K. Ogawa and T. Yokobe, Determination of small intestinal transit time in beagle dogs using salicylazosulfapylidine. Yakugaku Zasshi, 109, 760-765 (1989).
13. M.J. Vazquez, B. Perez-Marcos, J.L. Gomez-Amoza, R. Martinez-Pacheco, C. Souto and A. Concheiro, Influence of technological variables on release of drugs from hydrophilic matrics. Drug Dev. Ind. Pharm., 18, 1355-1375 (1992).
14. J.D. Smart, Some formulation factors influencing the rate of drug release from bioadhesive matrics, Drug Dev. Ind. Pharm., 18, 223-232 (1992).
15. Z. Hussein, M. Bialer, M Friedman and I. Raz, Comparative pharmacokinetic evaluation of sustained-release theophylline formulations in dogs and humans. Int. J. Pharm., 37, 97-102 (1987).
16. E. Rudnic and J.B. Schwartz, Oral solid dosage forms. In Remington's Pharmaceutical Sciences, A.R. Gennaro (Ed.), 18th edn, Mack, Pennsylvania, 1990, p. 1633.
17. M. Bialer, M. Friedman and J. Dubrovsky, Relation between absorption half-life values of four novel sustained release dosage forms of valproic acid in dogs and humans. Biopharm. Drug Dispos., 7, 495-501 (1986).
18. N. Aoyagi, H. Ogata, N. Kaniwa, M. Koibuchi, T. Shibazaki, A. Ejima, N. Tamaki, H. Kamimura, Y. Katougi and Y Omi, Bioavailability of griseofulvin from tablets in beagle dogs and correlation with dissolution rate and bioavailability in humans. J. Pharm. Sci., 71, 1169-1172 (1982).
19. K. Sagara, Y. Nagamatsu, I. Yamada, M. Kawata, H. Mizuta and K. Ogawa, Bioavailability study of commercial sustained-release preparations of diclofenac sodium in gastrointestinal physiology regulated-dogs. Chem. Pharm. Bull., 40, 3303-3305 (1992).
20. N. Katori, N. Aoyagi and S. Kojima, Effects of atropine and loperamide on the agitating force and GI transit time in dogs in drug absorption studies. Biol. Pharm. Bull., 19, 1338-1340 (1996).