A comparative study of FK506 granules and capsules in renal transplant recipients

Transplant International

Volumn 11, Issue 3, 1998, Pages 181-185

  Takahara, Shiro ^a   Miki, Tsuneharu ^a   Hatori, Motoaki ^a   Kokado, Yukito ^a   Wang, Jingding ^a   Okuyama, Akihiko ^a  

^a OSAKA UNIVERSITY MEDICAL SCHOOL   (Japan)

Author keywords

FK506 capsules; FK506 granules; Pharmacokinetics, FK506 granules

Indexed keywords

TACROLIMUS;

ADULT; AREA UNDER THE CURVE; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; DRUG BLOOD LEVEL; DRUG CAPSULE; DRUG EFFICACY; DRUG FORMULATION; DRUG GRANULE; DRUG SAFETY; FEMALE; HUMAN; KIDNEY FUNCTION; KIDNEY GRAFT REJECTION; KIDNEY TRANSPLANTATION; MALE; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL;

EID: 0031839406     PISSN: 09340874     EISSN: None     Source Type: Journal    
DOI: 10.1007/s001470050125     Document Type: Article

References (12)

1. Armitage JM, Kormos RL, Morita S, Fung J, Marrone GC, Hardesty RL, Griffith BP, Starzl TE (1992) Clinical trial of FK506 immunosuppression in adult cardiac transplantation. Ann Thorac Surg 54: 205-211
2. European FK506 Multicentre Liver Study Group (1994) Randomised trial comparing tacrolimus (FK506) and cyclosporin in prevention of liver allograft rejection Lancet 344: 423-428
3. Griffith BP, Bando K, Hardesty RL, Armitage JM, Keenan RJ, Pham SM, Paradis IL, Yousem SA, Komatsu K, Konishi H, Fung JJ, Starzl TE (1994) A prospective randomized trial of FK506 versus cyclosporine after human pulmonary transplantation. Transplantation 57: 848-851
4. Ihara H, Shinkuma D, Ichikawa Y, Nojima M, Nagano S, Ikoma F (1995) Intra-and interindividual variation in the pharmacokinetics of tacrolimus (FK506) in kidney transplant recipients - importance of trough level as a practical indicator. Int J Urol 2: 151-155
5. Japanese FK506 Study Group (1994) Two-year follow-up study of the efficacy and safety of FK506 in kidney transplant patients. Transpl Int 7 [Suppl]: S247-S251
6. Kino T, Hatanaka H, Hashimoto M, Nishiyama M, Goto T, Okuhara M, Kohsaka M, Aoki H, Imanaka H (1987) FK-506, a novel immunosuppressant isolated from a Streptomyces. I. Fermentation, isolation, and physicochemical and biological characteristics. J Antibiotics 40: 1249-1255
7. Kino T, Hatanaka H, Miyata S, Inamura N, Nishiyama M, Yajima T, Goto T, Okuhara M, Kohsaka M, Aoki H, Ochiai T (1987) FK-506, a novel immunosuppressant isolated from a Streptomyces. II. Immunosuppressive effect of FK-506 in vitro. J Antibiotics 40: 1256-1265
8. Kobayashi M, Tamura K, Katayama N, Nakamura K, Nagase K, Hane K, Tutumi T, Niwa M, Tanaka H, Iwasaki K, Kohsaka M (1991) FK 506 assay past and present - characteristics of FK 506 ELISA. Transplant Proc 23: 2725-2729
9. Masaoka T, Hiraoka A, Kanamaru A, Dohy H, Moriyama Y, Kodera Y, Okamoto S (1993) A multicenter study of FK 506 in patients with graft-versus-host disease after allogenic bone marrow transplantation. Transplant Now 6: 313-328
10. Ochiai T, Fukao K, Takahashi K, Endo T, Oshima S, Yokoyama I, Uchida K, Ishibashi M, Takahara S, Iwasaki S, Ota K, Takagi H, Ohashi Y, Sonoda T (1994) A phase III comparative study of FK506 (tacrolimus) on kidney transplantation - comparison with ciclosporin based immunosuppressant regimen. Jpn J Transplant 29: 650-681
11. Tanaka K, Uemoto S, Fujita S, Katoh H, Yamamoto E, Sano K, Nishizawa T, Sawada H, Yamaguchi T, Ozawa K (1992) Application of FK 506 to liver transplantation - experience with FK 506 in Living related liver transplantation. Transplant Now 5: 103-107
12. Todo S, Tzakis A, Abu-Elmagd K, Reyes J, Furukawa H, Nour B, Fung JJ, Starzl TE (1993) Clinical intestinal transplantation. Transplant Proc 25: 2195-2197