The use of thyroid supplements to augment antidepressant medication

Journal of Clinical Psychiatry

Volumn 59, Issue SUPPL. 5, 1998, Pages 26-31

  Joffe, Russell T ^a,b  

^a MCMASTER UNIVERSITY   (Canada)

^b MCMASTER UNIVERSITY MEDICAL CENTRE   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

BUSPIRONE; DESIPRAMINE; IMIPRAMINE; LEVOTHYROXINE; LEVOTHYROXINE SODIUM; LIOTHYRONINE; LIOTHYRONINE SODIUM; NORADRENALIN; PINDOLOL;

ARTICLE; BIOAVAILABILITY; DEPRESSION; DOSE RESPONSE; DRUG EFFICACY; DRUG MECHANISM; ENZYME INHIBITION; HUMAN; PRIORITY JOURNAL; RISK BENEFIT ANALYSIS; THYROID DISEASE; THYROID HORMONE BLOOD LEVEL;

EID: 0031839337     PISSN: 01606689     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (30)

1. Hall RCW. Psychiatric effects of thyroid hormone disturbance. Psychosomatics 1983;24:7-14
2. Fava GA, Sonino N, Morphy MA. Major depression associated with endocrine disease. Psychiatric Developments 1987;4:321-348
3. Joffe RT, Levitt AJ. The thyroid and depression. In: Joffe RT, Levitt AJ, eds. The Thyroid Axis and Psychiatric Illness. Washington, DC: American Psychiatric Press; 1993:195-254
4. Feldmeisser-Reiss EE. The application of triiodothyronine in the treatment of mental disorders. J Nerv Ment Dis 1958:127:540-543
5. Flach FF, Celian CI, Rawson RW. Treatment of psychiatric disorders with triiodothyronine. Am J Psychiatry 1958;114:841-846
6. Wilson IC, Prange AJ Jr, McClane TK, et al. Thyroid hormone enhance ment of imipramine in non-retarded depression. N Engl J Med 1970;282: 1063-1067
7. Wheatley D. Potentiation of amitriptyline by thyroid hormone. Arch Gen Psychiatry 1972;26:229-233
8. Feighner JP, King LJ, Schuckit MA, et al. Hormonal potentiation of imipramine and ECT in primary depression. Am J Psychiatry 1972;28:1230-1234
9. Earle BV. Thyroid hormone or tricyclic antidepressants in resistant depression. Am J Psychiatry 1970;126:1667-1669
10. Ogura C, Okuma T, Uchida Y, et al. Combined thyroid (triiodothyronine)-tricyclic antidepressant treatment in depressive states. Folia Psychiatr Neurol Jpn 1974;28:189-196
11. Banki CM. Triiodothyronine in the treatment of depression. Orv Hetil 1975;116:2543-2547
12. Tsutsui S, Tamazaki Y, Namba T. Combined therapy of T3 and antidepressants in depression. J Int Med Res 1979;7:138-146
13. Schwarcz G, Halaris A, Baxter L, et al. Normal thyroid function in desipramine non-responders converted to responders by the addition of L-triiodothyronine. Am J Psychiatry 1984;141:1614-1616
14. Thase ME, Kupfer DJ, Jarrett DB. Treatment of imipramine-resistant recurrent depression, I: an open clinical trial of adjunctive L-triiodothyronine. J Clin Psychiatry 1989;50:385-388
15. Banki CM. Cerebrospinal fluid amine metabolites after combined amitriptyline triiodothyronine treatment of depressed women. Eur J Clin Pharmacol 1977;11:311-315
16. Goodwin FK, Prange AJ Jr, Post RM, et al. Potentiation of antidepressant effects by L-triiodothyronine in tricyclic non-responders. Am J Psychiatry 1982;139:34-38
17. Joffe RT, Singer W. A comparison of triiodothyronine and thyroxine in the potentiation of tricyclic antidepressants. Psychol Res 1990;32:241-251
18. Joffe RT, Singer W, Levitt AJ, et al. A placebo-controlled comparison of lithium and triiodothyronine augmentation of tricyclic antidepressants in unipolar refractory depression. Arch Gen Psychiatry 1993;50:387-393
19. Gitlin MJ, Weiner H, Fairbanks L, et al. Failure of T3 to potentiate tricyclic antidepressant response. J Affect Disord 1987;13:267-272
20. Joffe RT. Triiodothyronine potentiation of antidepressant effect of phenelzine. J Clin Psychiatry 1988;49:409-410
21. Joffe RT. Triiodothyronine potentiation of fluoxetine in depressed patients. Can J Psychiatry 1992;37:48-50
22. Aronson R, Offman HJ, Joffe RT, et al. Triiodothyronine augmentation in the treatment of refractory depression: a meta-analysis. Arch Gen Psychiatry 1996;53:842-848
23. Targum SD, Greenberg RD, Harmon RL, et al. Thyroid hormone and the TRH stimulation test in refractory depression. J Clin Psychiatry 1984;45: 345-346
24. Whybrow PC, Prange AJ Jr. A hypothesis of thyroid-catecholamine-receptor interaction. Arch Gen Psychiatry 1981;38:106-111
25. Joffe RT, Roy-Byrne PP, Uhde TW, et al. Thyroid function in affective illness: a reappraisal. Biol Psychiatry 1984;19:1685-1691
26. Joffe RT, Levitt AJ, Bagby RM, et al. Predictors of response to lithium and triiodothyronine augmentation of antidepressants in tricyclic non-responders. Br J Psychiatry 1993;163:574-578
27. Sokolov STH, Levitt AJ, Joffe RT. The relationship between basal thyroid hormone levels and T3 augmentation response. Psychiatry Res 1997; 69:203-206
28. Joffe RT, Levitt AJ. Subclinical (Grade II) hypothyroidism and major depression. Psychoneuroendocrinology 1992;17:215-221
29. Joffe RT. T3 and lithium potentiation of tricyclic antidepressants. Am J Psychiatry 1988;145:1317-1318
30. Garbutt JC, Mayo MB Jr, Gillette GM, et al. Lithium potentiation of tricyclic antidepressants following lack of T3 potentiation. Am J Psychiatry 1986;143:1038-1039