Slow-release pellets of sodium butyrate increase apoptosis in the colon of rats treated with azoxymethane, without affecting aberrant crypt foci and colonic proliferation

Nutrition and Cancer

Volumn 30, Issue 3, 1998, Pages 175-181

  Caderni, Giovanna ^a   Luceri, Cristina ^a   Lancioni, Lorella ^a   Tessitore, Luciana ^b   Dolara, Piero ^a  

^a UNIVERSITY OF FLORENCE   (Italy)

^b UNIVERSITY OF TURIN   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

AZOXYMETHANE; BUTYRIC ACID; CORN OIL; SODIUM CHLORIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL PROLIFERATION; COLON CARCINOGENESIS; COLON MUCOSA; CONTROLLED STUDY; FEMALE; INTESTINE CRYPT; LIPID DIET; MALE; NONHUMAN; ORAL DRUG ADMINISTRATION; RAT; SLOW RELEASE FORMULATION; SUBCUTANEOUS DRUG ADMINISTRATION; TUMOR CELL LINE;

ANIMALIA; ZEA MAYS;

EID: 0031839010     PISSN: 01635581     EISSN: None     Source Type: Journal    
DOI: 10.1080/01635589809514660     Document Type: Article

References (26)

1. Bugaut, M, and Bentéjac, M: Biological effects of short-chain fatty acids in nonruminant mammals. Annu Rev Nutr 13, 217-241, 1993.
2. Clausen, MR: Butyrate and colorectal cancer in animals and in humans. Minisymposium: butyrate and colorectal cancer. Eur J Cancer Prev 4, 483-490, 1995.
3. Freeman, HJ: Effects of differing concentrations of sodium butyrate on 1,2-dimethylhydrazine-induced rat intestinal neoplasia. Gastroenterology 91, 596-602, 1986.
4. Deschner, EE, Ruperto, JF, Lupton, JR, and Newmark, HL: Dietary butyrate (tributyrin) does not enhance AOM-induced colon tumorigenesis. Cancer Lett 52, 79-82, 1990.
5. Caderni, G, Bianchini, F, Mancina, A, Spagnesi, MT, and Dolara, P: Effect of dietary carbohydrates on the growth of dysplastic crypt foci in the colon of rats treated with 1,2-dimethylhydrazine. Cancer Res 51, 3721-3725, 1991.
6. European Community: European Community Regulations on the Care and Use of Laboratory Animals, Law 86/609/EC, 1986.
7. Bird, RP: Observation and quantification of aberrant crypts in the murine colon treated with a colon carcinogen: preliminary findings. Cancer Lett 37, 147-151, 1987.
8. Corpet, DE, Stamp, D, Medline, A, Minkin, S, Archer, MA, et al.: Promotion of colonie microadenoma growth in mice and rats fed cooked sugar or cooked casein and fat. Cancer Res 50, 6955-6958, 1990.
9. Caderni, G, Giannini, A, Lancioni, L, Luceri, C, Biggeri, A, et al.: Characterisation of aberrant crypt foci in carcinogen-treated rats: association with intestinal cancerogenesis. Br J Cancer 71, 763-769, 1995.
10. Risio, M, Lipkin, M, Newmark, H, Yang, K, Rossini, FP, et al.: Apoptosis, cell replication, and Western-style diet-induced tumorigenesis in mouse colon. Cancer Res 56, 4910-4916, 1996.
11. Pouillart, P, Ronco, G, Cerutti, I, Trouvin, JH, Pieri, F, et al.: Pharmacokinetic studies of N-butyric acid mono-and polyesters derived from monosaccharides. J Pharm Sci 81, 241-244, 1992.
12. Bird, RP: Role of aberrant crypt foci in understanding the pathogenesis of colon cancer. Cancer Lett 93, 55-71, 1995.
13. Lipkin, M: Biomarkers of increased susceptibility to gastrointestinal cancer: new applications to studies of cancer prevention in human subjects. Cancer Res 48, 235-245, 1988.
14. Samaha, HS, Kelloff, GJ, Steele, V, Rao, CV, and Reddy, BS: Modulation of apoptosis by sulindac, curcumin, phenylethyl-3-methylcaffeate, and 6-phenylhexyl isothiocyanate: apoptotic index as a biomarker in colon cancer chemoprevention and promotion. Cancer Res 57, 1301-1305, 1997.
15. 1. Cancer Lett 63, 33-40, 1992.
16. Whitehead, RH, Young, GP, and Bhatal, PS: Effects of short chain fatty acids on a new human colon carcinoma cell line (LIM 1215). Gut 27, 1457-1463, 1986.
17. Hague, A, Manning, AM, Hanlon, KA, Huschtscha, LI, Hart, D, et al.: Sodium butyrate induces apoptosis in human colonie cell lines in a p53-independent pathway: implications for the possible role of dietary fibre in the prevention of large-bowel cancer. Int J Cancer 55, 498-505, 1993.
18. Hague, A, Elder, DJE, Hicks, DJ, and Paraskeva, C: Apoptosis in colorectal tumour cells: induction by the short chain fatty acids butyrate, propionate and acetate and by the bile salt deoxycholate. Int J Cancer 60, 400-406, 1995.
19. Heruth, DP, Zirnstein, GW, Bradley, JE, and Rothberg, PG: Sodium butyrate causes an increase in the block to transcriptional elongation in the c-myc gene in SW837 rectal carcinoma cells. J Biol Chem 268, 20466-20472, 1993.
20. Bianchini, F, Caderni, G, Magno, C, Testolin, G, and Dolara, P: Profile of short-chain fatty acids and rectal proliferation in rats fed sucrose or corn-starch diets. J Nutr 122, 254-261, 1992.
21. Hall, PA, Coates, PJ, Ansari, B, and Hopwood, D: Regulation of cell number in the mammalian gastrointestinal tract: the importance of apoptosis. J Cell Sci 107, 3569-3577, 1994.
22. Chang, WCL, Chapkin, RS, and Lupton, JR: Predictive value of proliferation, differentiation and apoptosis as intermediate markers for colon tumorigenesis. Carcinogenesis 18, 721-730, 1997.
23. Scheppach, W, Sommer, H, Kirchner, T, Paganelli, GM, Bartram, P, et al.: Effect of butyrate enemas on the colonie mucosa in distal ulcerative colitis. Gastroenterology 103, 51-56, 1992.
24. Tonelli, F, Dolara, P, Batignani, G, Monaci, I, Caderni, G, et al.: Effects of short chain fatty acids on mucosal proliferation and inflammation of ileal pouches in patients with ulcerative colitis and familial polyposis. Dis Colon Rectum 38, 974-978, 1995.
25. McIntryre, A, Gibson, PR, and Young, GP: Butyrate production from dietary fibre and protection against large bowel cancer. Gut 34, 386-391, 1993.
26. D'Argenio, G, Cosenza, V, Delle Cave, M, Iovino, P, Della Valle, N, et al.: Butyrate enemas in experimental colitis and protection against large bowel cancer in a rat model. Gastroenterology 110, 1727-1734, 1996.