In vitro inhibition of hepatic cytochrome P450 and enzyme activity by butyltin compounds in marine mammals

Environmental Pollution

Volumn 99, Issue 2, 1998, Pages 255-261

  Kim, Gi Beum ^a   Nakata, Haruhiko ^a   Tanabe, Shinsuke ^a  

^a EHIME UNIVERSITY   (Japan)

Author keywords

Butyltins; Cytochrome P450; Enzymatic inhibition; EROD; Marine mammals; PROD

Indexed keywords

BUTYLTIN; CYTOCHROME P450; DIBUTYLTIN; ETHOXYRESORUFIN DEETHYLASE;

ANIMAL TISSUE; ARTICLE; DOLPHIN; ENZYME ACTIVITY; LIVER; LIVER MICROSOME; NONHUMAN; SEAL;

ANIMALIA; CETACEA; MAMMALIA; PHOCIDAE; PINNIPEDIA;

EID: 0031838796     PISSN: 02697491     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0269-7491(97)00121-8     Document Type: Article

References (43)

1. Barnes, J.M., Magee, P.N., 1958. The biliary and hepatic lesion produced experimentally by dibutyltin salts J. Pathol. Bacteriol. 75, 267-279.
2. Boon, J.P., Van Arnhem, E., Jansen, S., Kannan, N., Petrick, G., Schulz, D., Duinker, J.C., Reijnders, P.J.H. and Goksøyr, A., 1992. The toxicokinetics of PCBs in marine mammals with special reference to possible interactions of individual congeners with the cytochrome P 450-dependent monooxygenase system: an overview. In: Walker, C.H., Livingstone, D.R. (Eds.), Persistent Pollutant in Marine Ecosystems. Pergamon Press. UK. pp. 119-159.
3. Boyer, I.J., 1989. Toxicity of dibutyltin. tributyltin and other organotin compounds to humans and to experimental animals. Toxicol. 55, 253-298.
4. Brüschweiler, B.J., Würgler, F.E., Fent, K., 1995. Cytotoxicity in vitro of organtin compounds to fish hepatoma cells PLHC-1 (Poecitiopsis lucida). Aquatic Toxicology 32, 143-160.
5. Brüschweiler, B.J., Würgler, F.E., Fent, K., 1996. Inhibition of cytochrome P4501A by organotins in fish hepatoma cells PLHC-1. Environmental Toxicology and Chemistry 15, 728-735.
6. Colborn, T., Smolen, M.J., 1996. Epidemiological analysis of persistent organochlorine contaminants in cetaceans. Rev. Environ. Contam. Toxicol. 146, 91-172.
7. Cummins, J.E., 1988. Extinction: the PCB threat to marine mammals. The Ecologist 18, 193-195.
8. Elferink, J.G.R., Deierkauf, M., Van Steveninck, J., 1986. Toxicity of organotin compounds for polymorphonuclear leukocytes: the effect on phagocytosis and exocytosis. Biochem. Pharmac. 35, 3727-3732.
9. Fent, K., Bucheli, T.D., 1994. Inhibition of hepatic microsomal monooxygenase system by organotins in vitro in freshwater fish. Aquatic Toxicology 28, 107-126.
10. Fent, K., Stegeman, J.J., 1991. Effects of tributyltin chloride on the hepatic microsomal monooxygenase system in the fish Stenotomus chrysops. Aquatic Toxicology 20, 159-168.
11. Fent, K., Stegeman, J.J., 1993. Effects of tribulyltin in vivo on hepatic cytochrome P450 forms inmarinefish. Aquatic Toxicology 24, 219-240.
12. Guengerich, F.P., 1982. Microsomal enzymes involved in toxicology -Analysis and separation. Principles and Methods Toxicol. 121, 609-634.
13. Iwata, H., Tanabe, S., Mizuno, T., Tatsukawa, R., 1995. High accumulation of toxic butyltins in marine mammals from Japanese coastal waters. Environmental Science and Technology 29, 2952-2962.
14. Kannan, K., Corsolini, S., Forcardi, S., Tanabe, S., Tatsukawa, R., 1996. Accumulation pattern of butyltin compounds in dolphin, tuna, and shark collected from Italian coatal waters. Archives of Environmental Contamination Toxicology 31, 19-23.
15. Kannan, K., Senthilkumar, K., Loganathan, B.G., Odell, D.K., Tanabe, S., 1997. Elevated levels of butyltin residues in bottlenose dolphins (Tursiops truncatus) stranded along the southeast US coast. Environmental Science and Technology 31, 296-301.
16. Kim, G.B., Tanabe, S., Tatsukawa, R., Loughlin, R., Shimazaki, K., 1996a. Characteristics of butyltin accumulation and its biomagnification in steller sea lion (Eumetopias jubatus). Environmental Toxicology and Chemistry 15, 2043-2048.
17. Kim, G.B., Tanabe, S., Iwakiri, R., Tatsukawa, R., Amano, M., Miyazaki, N., Tanaka, H., 1996b. Accumulation of butyltin compounds (Grampus griseus) from the Pacific coast of Japan: comparison with organochlorine residue pattern. Environmental Science and Technology 30, 2620-2625.
18. Kim, G.B., Lee, J.S., Tanabe, S., Iwata, H., Tatsukawa, R., Shimazaki, K., 1996c. Specific accumulation and distribution of butyltin compounds in various organs and tissues steller sea lion (Eumetopias jubatus): comparison with organochlorine accumulation pattern. Marine Pollution Bulletin 32, 558-563.
19. Kimmel, E.C., Fish, R.H., Casida, J.E., 1977. Bioorganotin chemistry. Metabolism of organotin compounds in microsomal monooxygenase systems and in mammals. J. Agric. Food Chem. 25, 1-9.
20. Laughlin Jr, R.B., Johannesen, R.B., French, W., Guard, H., Brinckman, F.F., 1985. Structure activity relationships for organotin compounds. Environmental Toxicology and Chemistry 4, 343-351.
21. Lee, R.F., 1986. Metabolism of bis(tributyltin)oxide by estuarine animals. In Proceedings of the Organotin Symposium Oceans '86. Washington, DC, IEEE and Marine Technology Society. New York, 1182-1188.
22. Lee, R.F., 1991. Metabolism of tributyltin by marine animals and possible linkages to effects. Marine Environment Research 32, 29-35.
23. Mizuno, T., 1997. Butyltin compound accumulation in high trophic-levels. M.Sc. thesis, Ehime University, Japan.
24. Norstrom, R.J., Muir, D.C.G., 1994. Chlorinated hydrocarbon contaminants in arctic marine mammals. The Science of the Total Environment 154, 107-128.
25. Penninks, A.H., Seinen, W., 1980. Toxicity of organotin compounds IV. Impairment of energy metabolism of rat thymocytes by various dialkyl compounds. Toxicology and Applied Pharmacology 56, 221-231.
26. Rosenberg, D.W., Drummond, G.S., 1983. Direct in vitro effects of bis(tri-n-butyltin)oxide on hepatic cytochrome P-450. Biochem. Pharmacol. 32, 3823-3829.
27. Rosenberg, D.W., Kappas, A., 1989. Actions of orally administered organotin compounds on heme metabolism and cytochrome P-450 content and function in intestinal epithelium. Biochem. Pharmacol. 38, 1155-1161.
28. Rosenberg, D.W., Drummond, G.S., Cornish, H.C., Kappas, A., 1980. Prolonged induction of hepatic haem oxygenase and decreases in cytochrome P-450 content by organotin compounds. Biochem. J. 190, 465-468.
29. Sato, R., Omura, T., 1978. In: Sato, R., Omura, T., (Eds.). Cytochrome P-450. Kodansha, Tokyo, Japan, pp. 1-135.
30. Seinen, W., 1980. Immunosuppression induced by certain organotin compounds. Vet. Sci. Commun. 3, 279-287.
31. Smith, P.J., Crowe, A.J., Kumar Das, V.G., Duncan, J., 1979. Structure-activity relationships for some organotin molluscicides. Pesticide Science 10, 419-422.
32. Snoeij, N.J., Punk, P.M., Penninks, A.H., Seinen, W., 1986a. Effects of tri-n-butyltin chloride on energy metabolism, macromolecular synthesis, precursor uptake and cyclic AMP production in isolated rat thymocytes. Biochim. Biophys. Acta 852, 234-243.
33. Snoeij, N.J., Van Iersel, A.A.J., Penninks, A.H., Seinen, W., 1986b. Triorganotin-induced cytotoxicity to rat thymus, bone marrow and red blood cells as determined by several in vitro assays. Toxicol. 39, 71-83.
34. Snoeij, N.J., Penninks, A.H., Seinen, W., 1987. Biological activity of organotin compounds - An overview. Environmental Research 44, 335-353.
35. Stegeman, J.J. and Hahn, M.E., 1994. Biochemistry and molecular biology of monooxygenase: Current perspectives on forms, functions, and regulation of cytochrome P450 in aquatic species. In: Malins, D.C., Ostrander, G.K. (Eds.), Aquatic Toxicology. Lewis Publishers, USA, pp. 87-206.
36. Stegeman, J.J., Kloepper-Sams, P.J., 1987. Cytochrome P-450 isozymes and monooxygenase activity in aquatic animals. Environ. Health Perspect. 71, 87-95.
37. Tan, L.P., Ng, M.L., Kumar Das, V.G., 1978. The effect of trialkyltin compounds on tubulin polymerisation. J. Neurochem. 31, 1035-1041.
38. Tanabe, S., 1988. PCB problems in the future: foresight from current knowledge. Environmental Pollution 50, 5-28.
39. Tanabe, S., Tatsukawa, R., 1992 Chemical modernization an vulnerability of cetaceans: increasing toxic threat of organochlorine contaminants. In: Walker C.H., Livingstone, D.R. (Eds.), Persistent Pollutants in Marine Ecosystems. Pergamon Press, UK, pp. 161-177.
40. Tanabe, S., Iwata, H., Tatsukawa, R., 1994. Global contamination by persistent organochlorines and their ecotoxicological impact on marine mammals. The Science of the Total Environment 154, 163-177.
41. Ueno, S., Susa, N., Furukawa, Y., Sugiyama, M., 1994. Comparison of hepatotoxicity caused by mono-, di- and tributyltin compounds in mice. Arch. Toxicol. 69, 30-34.
42. White, R.D., Hahn, M.E., Lockhart, W.L., Stegeman, J.J., 1994. Catalytic immunochemical characterization of hepatic microsomal cytochromes P450 in heluga whale (Delphinapterus leucas). Toxicology and Applied Pharmacology 126, 45-57.
43. Wong, P.T.S., Chau, Y.K., Kramar, O., Bengert, G.A., 1982. Structure-toxicity relationship of tin compounds on algae. Canadian Journal Fisheries and Aquatic Science 39, 483-488.