Sorbitol as a test substance for measurement of liver plasma flow in humans

Hepatology

Volumn 28, Issue 1, 1998, Pages 50-56

  Keiding, Susanne ^a,b   Engsted, Eva ^b   Ott, Peter ^b  

^a AARHUS UNIVERSITY HOSPITAL   (Denmark)

^b University of Copenhagen   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

INDOCYANINE GREEN; SORBITOL;

ADULT; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED STUDY; DRUG CLEARANCE; DRUG ELIMINATION; FEMALE; HEMODYNAMICS; HUMAN; INTRAVENOUS DRUG ADMINISTRATION; LIVER BLOOD FLOW; LIVER CIRRHOSIS; LIVER FUNCTION; LIVER METABOLISM; MALE; PRIORITY JOURNAL;

ADULT; AGED; AGED, 80 AND OVER; COLORING AGENTS; FEMALE; HOMEOSTASIS; HUMANS; INDICATORS AND REAGENTS; INDOCYANINE GREEN; LIVER CIRCULATION; LIVER DISEASES; MALE; MIDDLE AGED; MODELS, CARDIOVASCULAR; REFERENCE VALUES; SORBITOL;

EID: 0031837193     PISSN: 02709139     EISSN: None     Source Type: Journal    
DOI: 10.1002/hep.510280109     Document Type: Article

References (24)

1. Keiding S. Drug administration to liver patients: aspects of liver pathophysiology. Semin Liver Dis 1995;15:268-282.
2. Skak C, Keiding S. Methodological problems in the use of indocyanine green to estimate hepatic blood flow and ICG clearance in man. Liver 1987;7:155-162.
3. Ott P, Keiding S, Johnsen AH, Bass L. Hepatic removal of two fractions of indocyanine green after bolus injection in anaesthetized pigs. Am J Physiol 1994;266:G1108-G1122.
4. Molino G, Avagnina P, Cavanna A, Ballare M, Torchio M, Bona B, Belforte G. Sorbitol clearance: a parameter reflecting liver plasma flow in the rat. Res Commun Chem Pathol Pharmacol 1986;52:119-132.
5. Molino G, Cavanna A, Avagnina P, Ballare M, Torchio M. Hepatic clearance of D-sorbitol. Noninvasive test for evaluating functional liver plasma flow. Dig Dis Sci 1987;32:753-758.
6. Molino G, Avagnina P, Ballare M, Torchio M, Niro AG, Aurucci PE, Grosso M, et al. Combined evaluation of total and functional liver plasma flows and intrahepatic shunting. Dig Dis Sci 1991;36:1189-1196.
7. Zeeh J, Lange H, Bosch J, Pohl S, Loesgen H, Eggers R, Navasa M, et al. Steady-state extra-renal sorbitol clearance as a measure of hepatic plasma flow. Gastroenterology 1988;95:749-759.
8. Avagnina P, Martini M, Terzolo M, Sansoe G, Peretti P, Tinivella M, Pia A, et al. Assessment of functional liver mass and plasma flow in acromegaly before and after long-term treatment with octreotide. Metabolism 1996;45:109-113.
9. Avagnina P, Sansoe G, Martini M, Peretti P, Tinivella M, Molino G. Combined evaluation of total and functional liver plasma flows and intrahepatic shunting. Clin Pharmacol Ther 1993;53:368-373.
10. Molino G, Battista S, Bar F, Garello E, Avagnina P, Grosso M, Spalluto E Determination of functional portal-systemic shunting in patients submitted to hepatic angiography. Liver 1996;16:347-352.
11. Keiding S. Can intrahepatic shunting be measured? [Editorial]. Dig Dis Sci 1991;36:1185-1188.
12. Winkler K, Bass L, Keiding S, Tygstrup N. Physiologic basis of clearance measurements in HEPATOLOGY. Scand J Gastroenterol 1979;14:439-448.
13. Bergmeyer HU, Gruber W, Gutmann I. D-Sorbitol. In Methods of Enzymatic Analysis. HU Bergmeyer, ed. Weinheim, Verlag Chemie, 1975:1323-1330.
14. Ott P, Keiding S, Bass L. Plasma elimination of indocyanine green in the intact pig after bolus injection and during constant infusion: Comparison of spectrophotometry and HPLC for concentration analysis. HEPATOLOGY 1993;18:1504-1515.
15. Tygstrup N. Determination of the hepatic elimination capacity (Lm) of galactose by single injection. Scand J Clin Lab Invest 1966;18:131-138.
16. Tygstrup N. Effect of sites of blood sampling in determination of the galactose elimination capacity. Scand J Clin Lab Invest 1977;37:333-338.
17. Keiding S, Johansen S, Midotbll I, Rabol A, Christiansen L. Ethanol elimination kinetics in pig liver and human liver. Am J Physiol 1979;237:E316-E324.
18. Bass L, Keiding S, Winkler K, Tygstrup N. Enzymatic elimination of substrates flowing through the intact liver. J Theor Biol 1976;61:393-409.
19. Tygstrup N. The galactose elimination capacity in control subjects and in patients with cirrhosis of the liver. Acta Med Scand 1964;175:281-290.
20. Keiding S, Johansen S, Winkler K, Tonnesen K, Tygstrup N. Michaelis-Menten kinetics of galactose elimination by the isolated perfused pig liver. Am J Physiol 1976;230:1302-1313.
21. Weiss M, Hübner GH, Hübner IG, Teichmann W. Effects of cardiac output on disposition kinetics of sorbitol: recirculatory modelling. Br J Pharmacol 1996;41:261-268.
22. Keiding S. Dynamic aspects of hepatic removal of circulating substances. In: McIntyre N, Benhamou J-P, Bircher J, Rizzetto M, Rodes J, eds. Oxford Textbook of Clinical Hepatology. Oxford University Press, 1991:78-87.
23. Keiding S. Galactose clearance measurements and liver blood flow. Gastroenterology 1988;94:477-481.
24. Clemmesen O, Tygstrup N, Ott P. Evaluation of indocyanine green and D-sorbitol for estimate of hepatic plasma flow according to Fick's principle in patients with hepatic encephalopathy. HEPATOLOGY; in press.