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Volumn 31, Issue 2, 1998, Pages 253-260

Ionic effects of capsinolol, a calcitonin gene-related peptide releasing β-adrenoceptor blocker, on isolated cardiac muscles

Author keywords

adrenergic blockers; Action potential; Capsaicin analogue; Cardiac muscle; Twitch force

Indexed keywords

BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CALCITONIN GENE RELATED PEPTIDE RECEPTOR; CALCIUM ION; CAPSAICIN; CAPSINOLOL; NORADRENALIN; POTASSIUM ION; SODIUM ION; UNCLASSIFIED DRUG;

EID: 0031836688     PISSN: 03063623     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0306-3623(97)00449-7     Document Type: Article
Times cited : (3)

References (37)
  • 2
    • 85030191343 scopus 로고
    • Electrophysiological effects of capsaicin on the ventricular muscle and myocytes of guinea-pig
    • Aomine M. and Ehara T. (1993) Electrophysiological effects of capsaicin on the ventricular muscle and myocytes of guinea-pig. Jpn. J. Physiol. 43(Suppl. 2), s115.
    • (1993) Jpn. J. Physiol. , vol.43 , Issue.2 SUPPL.
    • Aomine, M.1    Ehara, T.2
  • 3
    • 0026100801 scopus 로고
    • Protons activate a sustained inward current in a sub-population of rat isolated dorsal root ganglion (DRG) neurones
    • Bevan S. and Yeats J. C. (1991) Protons activate a sustained inward current in a sub-population of rat isolated dorsal root ganglion (DRG) neurones. J. Physiol. 433, 145-161.
    • (1991) J. Physiol. , vol.433 , pp. 145-161
    • Bevan, S.1    Yeats, J.C.2
  • 4
    • 0025328825 scopus 로고
    • Sensory neuron-specific actions of capsaicin: Mechanisms and applications
    • Beven S. and Szolcsanyi J. (1990) Sensory neuron-specific actions of capsaicin: mechanisms and applications. Trends Pharmac. Sci. 11, 330-333.
    • (1990) Trends Pharmac. Sci. , vol.11 , pp. 330-333
    • Beven, S.1    Szolcsanyi, J.2
  • 5
    • 0025196889 scopus 로고
    • The effect of capsaicin on voltage-gated calcium currents and calcium signals in cultured dorsal root ganglion cells
    • Bleakman D., Brorson J. R. and Miller R. J. (1990) The effect of capsaicin on voltage-gated calcium currents and calcium signals in cultured dorsal root ganglion cells. Br. J. Pharmac. 101, 423-431.
    • (1990) Br. J. Pharmac. , vol.101 , pp. 423-431
    • Bleakman, D.1    Brorson, J.R.2    Miller, R.J.3
  • 6
    • 85047677273 scopus 로고
    • Differential inhibition of potassium currents in rat ventricular myocytes by capsaicin
    • Castle N. A. (1992) Differential inhibition of potassium currents in rat ventricular myocytes by capsaicin. Cardiovasc. Res. 26, 1137-1144.
    • (1992) Cardiovasc. Res. , vol.26 , pp. 1137-1144
    • Castle, N.A.1
  • 7
    • 0028201820 scopus 로고
    • Guaiacoxypropanolamine derivatives of capsaicin: A new family of β-adrenoceptor blockers with intrinsic cardiotonic properties
    • Chen I. J., Yeh J. L., Liou S. J. and Shen A. Y. (1994) Guaiacoxypropanolamine derivatives of capsaicin: a new family of β-adrenoceptor blockers with intrinsic cardiotonic properties. J. Med. Chem. 37, 938-943.
    • (1994) J. Med. Chem. , vol.37 , pp. 938-943
    • Chen, I.J.1    Yeh, J.L.2    Liou, S.J.3    Shen, A.Y.4
  • 8
    • 0029811699 scopus 로고    scopus 로고
    • Capsinolol: The first β-adrenoceptor blocker with an associated calcitonin gene-related peptide releasing activity in the heart
    • Chen I. J., Yeh J. L., Lo Y. C., Sheu S. H. and Lin Y. T. (1996) Capsinolol: the first β-adrenoceptor blocker with an associated calcitonin gene-related peptide releasing activity in the heart. Br. J. Pharmac. 119, 7-14.
    • (1996) Br. J. Pharmac. , vol.119 , pp. 7-14
    • Chen, I.J.1    Yeh, J.L.2    Lo, Y.C.3    Sheu, S.H.4    Lin, Y.T.5
  • 11
    • 0019393641 scopus 로고
    • A new interpretation of the pacemaker current in calf Purkinje fibres
    • DiFrancesco D. (1981) A new interpretation of the pacemaker current in calf Purkinje fibres. J. Physiol 314, 359-376.
    • (1981) J. Physiol , vol.314 , pp. 359-376
    • DiFrancesco, D.1
  • 12
    • 0025975788 scopus 로고
    • Capsaicin causes prolonged inhibition of voltage-activated calcium currents in adult dorsal root ganglion neurons in culture
    • Docherty R. J., Robertson B. and Bevan S. (1991) Capsaicin causes prolonged inhibition of voltage-activated calcium currents in adult dorsal root ganglion neurons in culture. Neuroscience 40, 513-521.
    • (1991) Neuroscience , vol.40 , pp. 513-521
    • Docherty, R.J.1    Robertson, B.2    Bevan, S.3
  • 13
    • 0023085778 scopus 로고
    • Intracellular and voltage clamp studies of capsaicin induced effects on a sensory neuron model
    • Erdelyi I., Such G. and Jancsó G. (1987) Intracellular and voltage clamp studies of capsaicin induced effects on a sensory neuron model. Acta Physiol. Hung. 69, 481-492.
    • (1987) Acta Physiol. Hung. , vol.69 , pp. 481-492
    • Erdelyi, I.1    Such, G.2    Jancsó, G.3
  • 14
    • 0001508993 scopus 로고
    • Properties of single capsaicin-activated channels
    • Forbes C. A. and Bevan S. J. (1988) Properties of single capsaicin-activated channels. Soc. Neurosci. Abstr. 14, 642.
    • (1988) Soc. Neurosci. Abstr. , vol.14 , pp. 642
    • Forbes, C.A.1    Bevan, S.J.2
  • 15
    • 0023910799 scopus 로고
    • Calicitonin gene-related peptide: Release by capsaicin and prolongation of the action potential in the guinea-pig heart
    • Franco-Cereceda A., Lundberg J. M., Saria A., Schreibmayer W. and Tritthart H. A. (1988) Calicitonin gene-related peptide: release by capsaicin and prolongation of the action potential in the guinea-pig heart. Acta Physiol. Scand. 132, 181-190.
    • (1988) Acta Physiol. Scand. , vol.132 , pp. 181-190
    • Franco-Cereceda, A.1    Lundberg, J.M.2    Saria, A.3    Schreibmayer, W.4    Tritthart, H.A.5
  • 16
    • 0028830161 scopus 로고    scopus 로고
    • Characterization of transient outward current in young human atrial myocytes
    • Gross G. J., Burke R. P. and Castle N. A. (1997) Characterization of transient outward current in young human atrial myocytes. Cardiovasc. Res. 29, 112-117.
    • (1997) Cardiovasc. Res. , vol.29 , pp. 112-117
    • Gross, G.J.1    Burke, R.P.2    Castle, N.A.3
  • 17
    • 0000217817 scopus 로고    scopus 로고
    • Catecholamines, sympathomimetic drugs, and adrenergic receptor antagonists
    • Edited by Hardman J. G., Gilman A. G. and Limbird L. E., McGraw-Hill, New York
    • Hoffman B. B. and Lefkowietz R. J. (1996) Catecholamines, sympathomimetic drugs, and adrenergic receptor antagonists. In Goodman and Gilman's Pharmacological Basis of Therapeutics (Edited by Hardman J. G., Gilman A. G. and Limbird L. E.), pp. 199-248. McGraw-Hill, New York.
    • (1996) Goodman and Gilman's Pharmacological Basis of Therapeutics , pp. 199-248
    • Hoffman, B.B.1    Lefkowietz, R.J.2
  • 18
    • 0025871477 scopus 로고
    • Capsaicin: Cellular targets, mechanisms of action and selectivity for thin sensory neurons
    • Holzer P. (1991) Capsaicin: cellular targets, mechanisms of action and selectivity for thin sensory neurons. Pharmac. Rev. 43, 143-201.
    • (1991) Pharmac. Rev. , vol.43 , pp. 143-201
    • Holzer, P.1
  • 19
    • 0017726385 scopus 로고
    • Time- and voltage-dependent interactions of antiarrhythmic drugs with cardiac sodium channels
    • Hondeghem L. M. and Katzung B. G. (1977) Time- and voltage-dependent interactions of antiarrhythmic drugs with cardiac sodium channels. Biochem. Biophys. Acta 472, 373-398.
    • (1977) Biochem. Biophys. Acta , vol.472 , pp. 373-398
    • Hondeghem, L.M.1    Katzung, B.G.2
  • 20
    • 0023199709 scopus 로고
    • Effects of calcitonin gene-related peptide (CGRP) and isoproterenol on the contractility and adenylate cyclase activity in the rat heart
    • Ishikawa T., Okamura N., Saito A. and Goto K. (1987) Effects of calcitonin gene-related peptide (CGRP) and isoproterenol on the contractility and adenylate cyclase activity in the rat heart. J. Mol. Cell. Cardiol. 19, 723-727.
    • (1987) J. Mol. Cell. Cardiol. , vol.19 , pp. 723-727
    • Ishikawa, T.1    Okamura, N.2    Saito, A.3    Goto, K.4
  • 21
    • 0028302489 scopus 로고
    • + currents in melantrophs of rat pituitary
    • + currents in melantrophs of rat pituitary. Br. J. Pharmac. 112, 616-624.
    • (1994) Br. J. Pharmac. , vol.112 , pp. 616-624
    • Kehl, S.J.1
  • 22
    • 0023920739 scopus 로고
    • Suppressive effects of somatostatin in dog Purkinje fibers
    • Lin C. I., Su M. T., Luk H. N. and Wu H. L. (1988) Suppressive effects of somatostatin in dog Purkinje fibers. Br. J. Pharmac. 93, 192-198.
    • (1988) Br. J. Pharmac. , vol.93 , pp. 192-198
    • Lin, C.I.1    Su, M.T.2    Luk, H.N.3    Wu, H.L.4
  • 23
    • 0028123430 scopus 로고
    • A rapid capsaicin-activated current in rat trigeminal ganglion cells
    • Liu L. and Simon S. A. (1994) A rapid capsaicin-activated current in rat trigeminal ganglion cells. Proc. Natl. Acad. Sci. USA 91, 738-741.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 738-741
    • Liu, L.1    Simon, S.A.2
  • 24
    • 0030941268 scopus 로고    scopus 로고
    • The responses of rat trigeminal ganglion neurons to capsaicin and two nonpungent vanilloid receptor agonists, olvanil and glyceryl nonivamide
    • Liu L., Lo Y. C., Chen I. J. and Simon S. A. (1997) The responses of rat trigeminal ganglion neurons to capsaicin and two nonpungent vanilloid receptor agonists, olvanil and glyceryl nonivamide. J. Neurosci. 17, 4101-4111.
    • (1997) J. Neurosci. , vol.17 , pp. 4101-4111
    • Liu, L.1    Lo, Y.C.2    Chen, I.J.3    Simon, S.A.4
  • 25
    • 0028913431 scopus 로고
    • Effect of capsaicin on membrane currents in cultured vascular smooth muscle cells of rat aorta
    • Lo Y. C., Wu S. N., Wu J. R. and Chen I. J. (1995) Effect of capsaicin on membrane currents in cultured vascular smooth muscle cells of rat aorta. Eur. J. Pharmac. 292, 321-328.
    • (1995) Eur. J. Pharmac. , vol.292 , pp. 321-328
    • Lo, Y.C.1    Wu, S.N.2    Wu, J.R.3    Chen, I.J.4
  • 26
    • 0023792484 scopus 로고
    • Depressant effects of isoflurane and halothane on isolated human atrial fibers
    • Luk H. N., Lin C. I., Wei J. and Chang C. L. (1988) Depressant effects of isoflurane and halothane on isolated human atrial fibers. Anesthesiology 69, 667-676.
    • (1988) Anesthesiology , vol.69 , pp. 667-676
    • Luk, H.N.1    Lin, C.I.2    Wei, J.3    Chang, C.L.4
  • 27
    • 0023833519 scopus 로고
    • The sensory-efferent function of capsaicin sensitive sensory neurons
    • Maggi C. A. and Meli A. (1988) The sensory-efferent function of capsaicin sensitive sensory neurons. Gen. Pharmac. 19, 1-43.
    • (1988) Gen. Pharmac. , vol.19 , pp. 1-43
    • Maggi, C.A.1    Meli, A.2
  • 28
    • 0023626285 scopus 로고
    • The mechanism and action of capsaicin on sensory C-type neurons and their axons in vitro
    • Marsh S. J., Stanefeld C. E., Brown D. A., Davey R. and McCarthy D. (1987) The mechanism and action of capsaicin on sensory C-type neurons and their axons in vitro. Neuroscience 23, 275-289.
    • (1987) Neuroscience , vol.23 , pp. 275-289
    • Marsh, S.J.1    Stanefeld, C.E.2    Brown, D.A.3    Davey, R.4    McCarthy, D.5
  • 29
    • 0025363645 scopus 로고
    • Electrophysiological and mechanical effects of calcitonin gene-related peptide on guinea-pig atria
    • Ohmura T., Nishio M., Kigoshi S. and Muramatsu I. (1990) Electrophysiological and mechanical effects of calcitonin gene-related peptide on guinea-pig atria. Br. J. Pharmac. 100, 27-30.
    • (1990) Br. J. Pharmac. , vol.100 , pp. 27-30
    • Ohmura, T.1    Nishio, M.2    Kigoshi, S.3    Muramatsu, I.4
  • 30
    • 0024378301 scopus 로고
    • Calcitonin-gene related peptide regulates calcium current in heart muscle
    • Ono K., Delay M., Nakajima T., Irisawa H. and Giles W. (1989) Calcitonin-gene related peptide regulates calcium current in heart muscle. Nature 340, 721-724.
    • (1989) Nature , vol.340 , pp. 721-724
    • Ono, K.1    Delay, M.2    Nakajima, T.3    Irisawa, H.4    Giles, W.5
  • 31
    • 0024447233 scopus 로고
    • Contractile effects of cardiac neuropeptides in isolated canine atrial and ventricular muscles
    • Rigel D. F., Grupp I. L., Balasubramaniam A. and Grupp G. (1989) Contractile effects of cardiac neuropeptides in isolated canine atrial and ventricular muscles. Am. J. Physiol. 257, H1082-1087.
    • (1989) Am. J. Physiol. , vol.257
    • Rigel, D.F.1    Grupp, I.L.2    Balasubramaniam, A.3    Grupp, G.4
  • 32
    • 0001954570 scopus 로고    scopus 로고
    • Antiarrhythmic drugs
    • Edited by Hardman J. G., Gilman A. G. and Limbird L. E., McGraw-Hill, New York
    • Roden D. M. (1996) Antiarrhythmic drugs. In Goodman and Gilman's Pharmacological Basis of Therapeutics (Edited by Hardman J. G., Gilman A. G. and Limbird L. E.), pp. 839-874. McGraw-Hill, New York.
    • (1996) Goodman and Gilman's Pharmacological Basis of Therapeutics , pp. 839-874
    • Roden, D.M.1
  • 33
    • 0017143158 scopus 로고
    • A metabolic control mechanism for calcium ion influx that may protect the ventricular myocardial cell
    • Sperelakis N. and Schneider J. A. (1976) A metabolic control mechanism for calcium ion influx that may protect the ventricular myocardial cell. Am. J. Cardiol. 37, 1079-1085.
    • (1976) Am. J. Cardiol. , vol.37 , pp. 1079-1085
    • Sperelakis, N.1    Schneider, J.A.2
  • 35
    • 0029967617 scopus 로고    scopus 로고
    • Inhibition of contractile tension by capsaicin in rat ventricular papillary muscle
    • Yamato T., Aomine M., Ikeda M., Noto H. and Ohat C. (1996) Inhibition of contractile tension by capsaicin in rat ventricular papillary muscle. Gen. Pharmac. 27, 129-132.
    • (1996) Gen. Pharmac. , vol.27 , pp. 129-132
    • Yamato, T.1    Aomine, M.2    Ikeda, M.3    Noto, H.4    Ohat, C.5
  • 36
    • 0026695786 scopus 로고
    • Arrhythmogenic mechanisms in human atrial and ventricular muscle fibers
    • Yeh T. C., Vassalle M. and Lin C. I. (1992) Arrhythmogenic mechanisms in human atrial and ventricular muscle fibers. Cardiology 80, 205-214.
    • (1992) Cardiology , vol.80 , pp. 205-214
    • Yeh, T.C.1    Vassalle, M.2    Lin, C.I.3
  • 37
    • 0021237199 scopus 로고
    • A study of the mode and site of action of capsaicin in guinea-pig heart and rat uterus
    • Zernig G., Holzer P. and Lembeck F. (1984) A study of the mode and site of action of capsaicin in guinea-pig heart and rat uterus. Naunyn-Schmiedeberg's Arch Pharmac. 326, 58-63.
    • (1984) Naunyn-Schmiedeberg's Arch Pharmac. , vol.326 , pp. 58-63
    • Zernig, G.1    Holzer, P.2    Lembeck, F.3


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