Relationship between parasite load and immune responses in early stages of Leishmania donovani infection in inbred BALB/c mice

East African Medical Journal

Volumn 75, Issue 3, 1998, Pages 156-159

  Wahinya, D N ^a   Mbati, P A ^a   Jomo, P M ^b   Githure, J I ^a  

^a KENYA MEDICAL RESEARCH INSTITUTE   (Kenya)

^b Kenya Polytech Institute   (Kenya)

Author keywords

[No Author keywords available]

Indexed keywords

AGGLUTINATION TEST; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELLULAR IMMUNITY; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMORAL IMMUNITY; LEISHMANIA DONOVANI; MOUSE; NONHUMAN; PARASITEMIA; SKIN TEST; VISCERAL LEISHMANIASIS;

AGGLUTINATION TESTS; ANIMALS; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; ENZYME-LINKED IMMUNOSORBENT ASSAY; LEISHMANIA DONOVANI; LEISHMANIASIS, VISCERAL; MICE; MICE, INBRED BALB C; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SKIN TESTS;

ANIMALIA; LEISHMANIA DONOVANI;

EID: 0031836584     PISSN: 0012835X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (11)

1. Pearson, R.D. and Sousa, A.O. Leishmania species: visceral (kalaazar), cutaneous and mucocutaneous leishmaniasis. Mandell, G.L., Douglas, R.G., Bennet, J.E., (eds). Principles and practice of infectious disease. Third edition. New York: Churchill Livingstone, pp. 2066-2077.
2. Voller, A., Bartelett, A. and Bidwell, D.E. Enzyme immunoassays for parasitic diseases. Trans. roy Soc. trop. Med. Hyg. 197 6; 70:98-106.
3. Thakur, C.P. and Kumar, K. Post kala azar dermal leishmaniasis: a neglected aspect of kalaazar control programs. Ann. trop. Med. Parasit. 1992; 86:355-359.
4. Chang, K.P. Cellular and molecular mechanisms of intracellular symbiosis in leishmaniasis. Intern. Rev. Cytology. 1983; 14:267-276.
5. Mbati, P.A., Anjili, C.O., Lugalia, Tonui, E.K.R., Robert, I. and Githure, J.I. Experimental immunization against cutaneous leishmaniasis using Leishmania major subcellular fractions alone in combination with phlebotomus duboscqi gut antigens. East Afr. Med. J. 1995; 72:519-522.
6. Mbati, P.A., Abok, K., Orago, A.S., Anjili, C.O., Kagai, J.M., Githure, J.I. and Koech, D.K. Establishment of an appropriate inoculum dose of Leishmania donovani promastigotes required to establish a visceral infection in laboratory animal rodent models. Afr. J. Hlth. Sci. 1994; 1:165-168.
7. Mbati, P.A., Anjili, C.O., Kagai, J.M. and Githure, J.I. Giemsa and Acridine Orange stains: A laboratory experience in the diagnosis of leishmaniasis. East Afr. Med. J. 1993; 70:466-467.
8. Mbati, P.A. Use of chelators in the Experimental Chemotherapy of Visceral Leishmaniasis. PhDthesis, 1994. Kenyatta University, Kenya.
9. Lowry, O.H., Rosenbrough, N.J., Farr, A.L. and Randall, R.J. Protein measurements with folin phenol reagent J. Biological. Chem. 1951; 193:263-275.
10. Harith, A.E., Laarman, J.J., Minter-Goedbloed, E., Kager, P.A. and Kolk, A.H.J. Trypsin treated and Coomasie blue epimastigote antigen in micro agglutination test for Chagas disease. Amer. J. trop. Med. Hyg. 1987; 37:66.
11. Mwaniki, J.K., Muigai, R., Mbati, P.A. and Githure, J.J. Use of beef extract as a diluent in Direct Agglutination Test for Visceral leishmaniasis. East Afr. Med. J. 1992; 69:244-247.