RXR agonists activate PPARα-inducible genes, lower triglycerides, and raise HDL levels in vivo

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 18, Issue 2, 1998, Pages 272-276

  Mukherjee, Ranjan ^a   Strasser, Josef ^a   Jow, Lily ^a   Hoener, Patricia ^a   Paterniti Jr , James R ^a   Heyman, Richard A ^a  

^a LIGAND PHARMACEUTICALS INC   (United States)

Author keywords

Hypertriglyceridemia; Low HDL; PPAR; Rexinoids; RXR

Indexed keywords

ACYL COENZYME A OXIDASE; ANTILIPEMIC AGENT; APOLIPOPROTEIN A1; BEXAROTENE; GEMFIBROZIL; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LDG 100268; LGD 100268; MESSENGER RNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR; RETINOID X RECEPTOR; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

ADOLESCENT; ANIMAL MODEL; ARTICLE; DRUG EFFICACY; DRUG MECHANISM; ENZYME INDUCTION; FEMALE; GENE EXPRESSION; HYPERLIPIDEMIA; MALE; MOUSE; NONHUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION;

EID: 0031836567     PISSN: 10795642     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.ATV.18.2.272     Document Type: Article

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