Skin and plasma levels of acetylsalicylic acid: A comparison between topical aspirin/diethyl ether mixture and oral aspirin in acute herpes zoster and postherpetic neuralgia

European Journal of Clinical Pharmacology

Volumn 54, Issue 3, 1998, Pages 231-235

  Bareggi, S R ^a   Pirola, R ^a   De Benedittis, G ^a  

^a UNIVERSITY OF MILAN   (Italy)

Author keywords

Herpetic neuralgia; Pharmacokinetics; Topical aspirin

Indexed keywords

ACETYLSALICYLIC ACID; ETHER;

ADULT; AGED; ANALGESIA; ARTICLE; CLINICAL ARTICLE; DRUG BLOOD LEVEL; DRUG EFFICACY; DRUG MIXTURE; FEMALE; HERPES ZOSTER; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; MALE; ORAL DRUG ADMINISTRATION; PLASMA; POSTHERPETIC NEURALGIA; PRIORITY JOURNAL; SKIN; TOPICAL DRUG ADMINISTRATION;

ACUTE DISEASE; ADMINISTRATION, ORAL; ADMINISTRATION, TOPICAL; AGED; ANALGESICS; ANTI-INFLAMMATORY AGENTS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ASPIRIN; CROSS-OVER STUDIES; DOUBLE-BLIND METHOD; ETHER, ETHYL; FEMALE; HERPES ZOSTER; HERPESVIRIDAE INFECTIONS; HUMANS; MALE; MIDDLE AGED; NEURALGIA; PAIN; PAIN MEASUREMENT; SALICYLIC ACID; SALICYLIC ACIDS; SKIN; SOLVENTS; TREATMENT OUTCOME;

EID: 0031836433     PISSN: 00316970     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002280050451     Document Type: Article

References (23)

1. Loeser JD (1986) Herpes zoster and postherpetic neuralgia. Pain 25: 149-164
2. Portenoy RK, Duma C, Foley KM (1986) Acute herpetic and postherpetic neuralgia: clinical review and current management. Ann Neurol 20: 651-664
3. Watson CPN, Evans RJ, Watt VR, Birkett N (1988) Postherpetic neuralgia: 208 cases. Pain 35: 289-297
4. Bernstein JE, Bickers DR, Dahl MV, Roshal JY (1987) Treatment of chronic postherpetic neuralgia with topical capsaicin J Am Acad Dermatol 17: 93-96
5. Drake HF, Harries AJ, Gamester RE, Justins D (1990) Randomized double-blind study of topical capsaicin for treatment of post-herpetic neuralgia. Pain [suppl] 5: S58
6. Watson CPN, Evans RJ, Watt VR (1988) Post-herpetic neuralgia and topical capsaicin. Pain 33: 333-340
7. Rowbotham MC, Fields HL (1989) Post-herpetic neuralgia: the relation of pain complaint, sensory disturbance and skin temperature. Pain 39: 129-144
8. Rowbotham MC, Fields HL (1989) Topical lidocaine reduces pain in post-herpetic neuralgia. Pain 39: 297-301
9. Rowbotham MC, Davies PS, Verkempinck C, Galer BS (1996) Lidocaine patch: double-blind controlled study of a new treatment method of post-herpetic neuralgia. Pain 65: 39-45
10. King RB (1988) Concerning the management of pain associated with herpes zoster and postherpetic neuralgia. Pain 33: 73-78
11. King RB (1993) Topical aspirin in chloroform and the relief of pain due to herpes zoster and postherpetic neuralgia. Arch Neurol 50: 1046-1053
12. Morimoto M, Inamori K, Hyodo M (1990) The effect of indomethacin stupe for post-herpetic neuralgia - particularly in comparison with chloroform-aspirin solution. Pain [suppl] 5: S59
13. De Benedittis G, Lorenzetti A, Besana F (1992) A new topical treatment for acute herpetic neuralgia and post-herpetic neuralgia: the aspirin/diethyl ether mixture. An open-label study plus a double-blind controlled clinical trial. Pain 48: 383-391
14. De Benedittis G, Lorenzetti A (1996) Topical aspirin diethyl ether mixture for acute herpetic neuralgia and postherpetic neuralgia: a double-blind crossover placebo-controlled study. Pain 65: 45-51
15. Ferreira SH, Lorenzetti BB, Correa FMA (1978) Central and peripheral antialgesic action of aspirin-like drues. Eur J Pharmacol 53: 39-48
16. Yaksh TL, Farb DH, Leeman SE, Jessell TM (1979) Intrathecal capsaicin depletes substance P in the rat spinal cord and produces prolonged thermal analgesia. Science 206: 481-483
17. Rougier A, Lotte C, Maibach HI (1986) In vivo percutaneous penetration of some organic compounds related to anatomic site in humans: predictive assessment by the stripping method. J Pharm Sci 76: 451-454
18. Pirola R, Bareggi SR, De Benedittis G (1998) HPLC analysis of acetylsalicylic acid and salicylic acid in the skin and plasma. J Chromatogr 705: 309-315
19. Davison C (1971) Salicylate metabolism in man. Ann NY Acad Sci 179: 249-268
20. Vane JR (1971) Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs. Nature 231: 232-235
21. Watson CPN, Evans RJ (1986) Postherpetic neuralgia: a review. Arch Neurol 43: 836-840
22. Levitann H, Barker JL (1972) Membrane permeability: cation selectivity reversibly altered by salicylate. Science 178: 63-64
23. Barbi M, Binda S, Primache V, De Benedittis G (1998) In vitro activity of aspirin on replication of varicella-zoster virus Microbiologica (in press)