Effect of anion secretion inhibitors on mucin content of airway submucosal gland ducts

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 274, Issue 5 18-5, 1998, Pages

  Inglis, Sarah K ^a   Corboz, Michel R ^a   Ballard, Stephen T ^a,b  

^a UNIVERSITY OF SOUTH ALABAMA COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF SOUTH ALABAMA   (United States)

Author keywords

Acetylcholine; Airway epithelium; Bicarbonate secretion; Bronchi; Cystic fibrosis; Mucus

Indexed keywords

ACETAZOLAMIDE; ACETYLCHOLINE; BICARBONATE; BUMETANIDE; MUCIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANION TRANSPORT; ARTICLE; CYSTIC FIBROSIS; ENZYME ACTIVITY; MUCOSA CELL; NONHUMAN; PRIORITY JOURNAL; RESPIRATORY EPITHELIUM; SWINE;

EID: 0031836088     PISSN: 10400605     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajplung.1998.274.5.l762     Document Type: Article

References (22)

1. Ballard, S. T., J. D. Fountain, S. K. Inglis, M. R. Corboz. and A. E. Taylor. Chloride secretion across distal airway epithelium: relationship to submucosal gland distribution. Am. J. Physiol. 268 (Lung Cell. Mol. Physiol. 12): L526-L531, 1995.
2. + transport in cystic fibrosis respiratory epithelia. J. Clin. Invest. 78: 1245-1252, 1986.
3. Case, R. M., and B. E. Argent. Pancreatic duct cell secretion. Control and mechanisms of transport. In: The Pancreas: Biology, Pathobiology and Disease (2nd ed.), edited by V. L. W. Go, E. P. DiMagno, J. D. Gardner, E. Lebenthal, H. A. Reber, and G. A. Scheele. New York: Raven, 1993, p. 301-350.
4. + transport properties of isolated rat parotid acini. Am. J. Physiol. 259 (Gastrointest. Liver Physiol. 22): G1044-G1055, 1990.
5. Engelhardt, J. F., J. R. Yankaskas, S. A. Ernst, Y. Yang, C. R. Maino, R. C. Boucher, J. A. Cohn, and J. M. Wilson. Submucosal glands are the predominant site of CFTR expression in the human bronchus. Nat. Genet. 2: 240-248, 1992.
6. + transport processes in isolated guinea pig nasal gland acinar cells. J. Cell. Physiol. 163: 204-209, 1995.
7. Inglis, S. K., M. R. Corboz, A. E. Taylor, and S. T. Ballard. Regulation of ion transport across porcine distal bronchi. Am. J. Physiol. 270 (Lung Cell. Mol. Physiol. 14): L289-L297, 1996.
8. Inglis, S. K., M. R. Corboz, A. E. Taylor, and S. T. Ballard. In situ visualization of bronchial submucosal glands and their secretory response to acetylcholine. Am. J. Physiol. 272 (Lung Cell. Mol. Physiol. 16): L203-L210, 1997.
9. Inglis, S. K., M. R. Corboz, A. E. Taylor, and S. T. Ballard. Effect of anion transport inhibition on mucus secretion by airway submucosal glands. Am. J. Physiol. 272 (Lung Cell. Mol. Physiol. 16): L372-L377, 1997.
10. Jiang, C., W. E. Finkbeiner, J. H. Widdicombe, P. B. McCray, Jr., and S. S. Miller. Altered fluid transport across airway epithelium in cystic fibrosis. Science 262: 424-427, 1993.
11. Leikauf, G. D., I. F. Ueki, and J. A. Nadel. Autonomic regulation of viscoelasticity of cat tracheal gland secretions. J. Appl. Physiol. 56: 426-430, 1984.
12. Luk, C. K., and M. J. Dulfano. Effect of pH, viscosity and ionic-strength changes on ciliary beating frequency of human bronchial explants. Clin. Sci. 64: 449-451, 1983.
13. Minhas, B. S., S. K. Sullivan, and M. Field. Bicarbonate secretion in rabbit ileum: electrogenicity, ion dependence and effects of cyclic nucleotides. Gastroenterology 105: 1617-1629, 1993.
14. Nauntofte, B. Regulation of electrolyte and fluid secretion in salivary acinar cells. Am. J. Physiol. 263 (Gastrointest. Liver Physiol. 26): G823-G837, 1992.
15. Quinton, P. M. Composition and control of secretions from tracheal bronchial submucosal glands. Nature 279: 551-552, 1979.
16. + activity measurements. J. Membr. Biol. 98: 135-144, 1987.
17. Sheppard, M. N. The pathology of cystic fibrosis. In: Cystic Fibrosis, edited by M. E. Hudson and D. M. Geddes. London: Chapman & Hall, 1995, p. 131-149.
18. Smith, J. J., and M. J. Welsh. cAMP stimulates bicarbonate secretion across normal, but not cystic fibrosis airway epithelia. J. Clin. Invest. 89: 1148-1153, 1992.
19. Tam, P. Y., and P. Verdugo. Control of mucus hydration as a Donnan equilibrium process. Nature 292: 340-342, 1981.
20. - secretion by Clara cells. Am. J. Respir. Cell Mol. Biol. 13: 344-351, 1995.
21. Welsh, M. J., and A. E. Smith. Molecular mechanisms of CFTR chloride channel dysfunction in cystic fibrosis. Cell 73: 1251-1254, 1993.
22. i in pancreatic acinar cells. J. Gen. Physiol. 106: 1243-1263, 1995.