Apoptosis and spinal cord injury

Neuroscientist

Volumn 4, Issue 3, 1998, Pages 163-171

  Beattie, Michael S ^a,b   Shuman, Sheri L ^a   Bresnahan, Jacqueline C ^a  

^a THE OHIO STATE UNIVERSITY COLLEGE OF MEDICINE   (United States)

^b THE OHIO STATE UNIVERSITY WEXNER MEDICAL CENTER   (United States)

Author keywords

Apoptosis; Axons; Injury; Oligodendrocytes; Spinal cord

Indexed keywords

CYCLOHEXIMIDE; INTERLEUKIN 1BETA CONVERTING ENZYME; METHYLPREDNISOLONE; PROTEINASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; BRAIN INJURY; BRAIN ISCHEMIA; CELL PROLIFERATION; CONTUSION; DEMYELINATION; DRUG MECHANISM; EPENDYMOMA; GLIA; HUMAN; NERVE CELL NECROSIS; NERVE DEGENERATION; NONHUMAN; OLIGODENDROGLIA; REVIEW; SPINAL CORD INJURY;

EID: 0031836062     PISSN: 10738584     EISSN: None     Source Type: Journal    
DOI: 10.1177/107385849800400312     Document Type: Review

References (68)

1. Raff MC, Barres BA, Burne JF, Coles HS, Ishizaki Y, Jacobson MD. Programmed cell death and the control of cell survival: lessons from the nervous system. Science 1993;262:695-700.
2. Nagata S. Apoptosis by death factor. Cell 1997;88:355-365.
3. Portera-Cailliau C, Price DL, Martin LJ. Excitotoxic neuronal death in the immature brain is an apoptosis-necrosis morphological continuum. J Comp Neurol 1997;378:70-87.
4. Jacobson MD, Weil M, Raff MC. Programmed cell death in animal development. Cell 1997;88:347-354.
5. Stellar H. Mechanisms and genes of cellular suicide. Science 1995;267:1445-1449.
6. Payne CM, Bernstein C, Bernstein H. Apoptosis overview emphasizing the role of oxidative stress, DNA damage and signal-transduction pathways. Leuk Lymphoma 1995;19:43-93.
7. Chopp M, Chan PH, Hsu CY, Cheung ME, Jacobs TP. DNA damage and repair in central nervous system injury: National Institute of Neurological Disorders and Stroke workshop summary. Stroke 1996;27:363-369.
8. Johnson EM, Greenlund LJS, Akins PT, Hsu CY. Neuronal apoptosis: current understanding of molecular mechanisms and potential role in ischemic brain injury. J Neurotrauma 1995;12:843-852.
9. Bredesen DE. Keeping neurons alive: the molecular control of apoptosis (part I). NEUROSCIENTIST 1996;2:181-190.
10. Crowe MJ, Bresnahan JC, Shuman SL, Masters JN, Beattie MS. Apoptosis and delayed degeneration after spinal cord injury in rats and monkeys. Nature Med 1997;3:73-76.
11. Shuman SL, Bresnahan JC, Beattie MS. Apoptosis of microglia and oligodendrocytes after spinal cord injury in rats. J Neurosci Res 1997;50:798-808.
12. Beattie MS, Bresnahan JC, Komon J, et al. Endogenous repair after spinal cord contusion injuries in the rat. Exp Neurol 1997; 148:453-463.
13. Noble L, Wrathall J. Spinal cord contusion in the rat: morphometric analyses of alterations in the spinal cord. Exp Neurol 1985; 88:135-149.
14. Stokes BT, Behrmann DL, Noyes DH. An electromechanical spinal cord injury device with dynamic sensitivity. J Neurotrauma 1992;9:187-195.
15. Behrmann DL, Bresnahan JC, Beattie MS, Shah BR. Spinal cord injury produced by consistent mechanical displacement of the cord in rats: behavioral and histologic analysis. J Neurotrauma 1992;9: 197-217.
16. Behrmann DL, Bresnahan JC, Beattie MS. Modeling of acute spinal cord injury in the rat: neuroprotection and enhanced recovery with methylprednisolone, U-74006F and YM-14673. Exp Neurol 1994;126:61-75.
17. Bresnahan JC, Beattie MS, Todd FD, Noyes DH. A behavioral and anatomical analysis of spinal cord injury produced by a feedback-controlled impaction device. Exp Neurol 1987;95:548-570.
18. Gruner JA. A monitored contusion model of spinal cord injury in the rat. J Neurotrauma 1992;9:123-128.
19. Constantini S, Young W. The effects of methylprednisolone and the ganglioside GM1 on acute spinal cord injury in rats. J Neurosurg 1994;80:97-111.
20. Basso DM, Beattie MS, Bresnahan JC. Graded histological and locomotor outcomes after spinal cord contusion using the NYU weight-drop device versus transection. Exp Neurol 1996;139:244-256.
21. Basso DM, Beattie MS, Bresnahan JC, et al. MASCIS evaluation of open field locomotor scores: effects of experience and teamwork on reliability. J Neurotrauma 1996;13:343-359.
22. Wrathall JR, Teng YD, Choiniere D. Amelioration of functional deficits from spinal cord trauma with systemically administered NBQX, an antagonist of non-N-methyl-D-aspartate receptors. Exp Neurol 1996;137:119-26.
23. Beattie MS, Stokes BT, Bresnahan JC. Experimental spinal cord injury: Strategies for chronic and acute intervention based on anatomic, physiological, and behavioral studies. In: Stein DG, Sabel BA, editors. Pharmacological approaches to the treatment of brain and spinal cord injury. New York: Plenum Press; 1988. p. 43-74.
24. Dusart I, Schwab ME. Secondary cell death and the inflammatory reaction after dorsal hemisection of the rat spinal cord. Eur J Neurosci 1994;6:712-724.
25. Choi DW. Ischemia-induced neuronal apoptosis. Curr Opin Neurobiol 1996;6:667-672.
26. Johnson EM Jr, Greenlund LJS, Akins PT, Hsu CY. Neuronal apoptosis: current understanding of molecular mechanisms and potential role in ischemic brain injury. J Neurotrauma 1995;12: 843-852.
27. Hall ED, Yonkers PA, Taylor BM, Sun FF. Lack of effect of post-injury treatment with methylprednisolone or tirilazad mesylate on the increase in eicosanoid levels in the acutely injured cat spinal cord. J Neurotrauma 1995;12:245-256.
28. Blight AR. Macrophages and inflammatory damage in spinal cord injury. J Neurotrauma 1992;9(suppl. 1):S83-S92.
29. Jiang N, Moyle M, Soule HR, Rote WE, Chopp M. Neutrophil inhibitory factor is neuroprotective after focal ischemia in rats. Ann Neurol 1995;38:935-942.
30. Popovich PG, Wei P, Stokes BT. Cellular inflammatory response after spinal cord injury in Sprague-Dawley and Lewis rats. J Comp Neurol 1997;377:443-464.
31. Kerr JFR, Wyllie AH, Currie AR. Apoptosis: a basic biological phenomenon with wide ranging implication in tissue kinetics. Br J Cancer 1972;26:239-257.
32. Gavrieli Y, Sherman Y, Ben-Sassonm SA. Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. J Cell Biol 1992;119:493-501.
33. Deckwerth TL, Johnson EM Jr. Temporal analysis of events associated with programmed cell death (apoptosis) of sympathetic neurons deprived of nerve growth factor. J Cell Biol 1993;123: 1207-1222.
34. Motoyama N, Wang F, Roth KA, et al. Massive cell death of immature hematopoietic cells and neurons in Bcl-x-deficient mice. Science 1995;267:1506-1510.
35. Beattie MS, Bresnahan JC, Masters JN, et al. Incidence of apoptotic nuclear profiles in Xenopus laevis central nervous system is increased by exogenous thyroid hormone exposure (abstract). Soc Neurosci Abstr 1995;21:1305.
36. Rink A, Fung KM, Trojanowski JQ, Lee VMY, Neugebauer E, McIntosh TK. Evidence of apoptotic cell death after experimental traumatic brain injury in the rat. Am J Pathol 1995;147:1575-1583.
37. Berkelaar M, Clarke DB, Wang YC, Bray GM, Aguayo AJ. Axotomy results in delayed death and apoptosis of retinal ganglion cells in adult rats. J Neurosci 1994;14:4368-4374.
38. Li GL, Brodin G, Farooque M, et al. Apoptosis and expression of Bcl-2 after compression trauma to rat spinal cord. J Neuropathol Exp Neurol 1996;55:280-289.
39. Liu XZ, Xu XM, Hu R, et al. Neuronal and glial apoptosis after traumatic spinal cord injury. J Neurosci 1997;17:5395-5406.
40. Friedman B, Hockfield S, Black JA, Woodruff KA, Waxman SG. In situ demonstration of mature oligodendrocytes and their processes: an immunocytochemical study with a new monoclonal antibody, rip. Glia 1989;2:380-390.
41. Bhat RV, Axt KJ, Fosnaugh JS, et al. Expression of the APC tumor suppressor protein in oligodendroglia. Glia 1996;17:169-174.
42. Bresnahan JC, King JS, Martin GF, Yashon D. A neuroanatomical analysis of spinal cord injury in the rhesus monkey (Macaca mulatta). J Neurol Sci 1976;28:521-542.
43. Bresnahan JC. An electron-microscopic analysis of axonal alterations following blunt contusion of the spinal cord of the rhesus monkey (Macaca mulatta). J Neurol Sci 1978;37:59-82.
44. Allen AR. Surgery of experimental lesion of spinal cord equivalent to crush injury or fracture dislocation of spinal column: a preliminary report. JAMA 1911;57:870-880.
45. Fink RP, Heimer L. Two methods for selective silver impregnation of degenerating axons and their synaptic ends in the central nervous system. Brain Res 1967;4:369-374.
46. Bunge RP, Puckett WR, Becerra JL, Marcillo A, Quencer RM. Observations of the pathology of human spinal cord injury: a review and classification of 22 new cases with details from a case of cord compression with extensive focal demyelination. Adv Neurol 1993;59:75-89.
47. Blight A, Decrescito V. Morphometric analysis of experimental spinal cord injury in the cat: the relation of injury intensity to survival of myelinated axons. Neuroscience 1986;19:321-341.
48. Barres BA, Jacobsen MD, Schmid R, Sendtner M, Raff MC. Does oligodendrocyte survival depend on axons? Curr Biol 1993;3:489-497.
49. Barres BA, Schmid R, Sendtner M, et al. Multiple extracellular signals are required for long term oligodendrocyte survival. Development 1993;118:283-295.
50. Burden S, Yarden Y. Neuregulins and their receptors: a versatile signaling module in organogenesis and oncogenesis. Neuron 1997; 18:847-855.
51. Zhang ZY, Fujiki M, Guth L, Steward O. Genetic influences on cellular reactions to spinal cord injury: a wound-healing response present in normal mice is impaired in mice carrying a mutation (WldS) that causes delayed Wallerian degeneration. J Comp Neurol 1996;371:485-495.
52. Vartanian T, Goodearl A, Viehöver A, Fischbach G. Axonal neuregulin signals cells of the oligodendrocyte lineage through activation of HER4 and Schwann cells through HER2 and HER3. J Cell Biol 1997;137:211-220.
53. Vartanian T, Li Y, Zhao M, et al. Interferon-gamma-induced oligodendrocyte cell death: implications for the pathogenesis of multiple sclerosis. Mol Med 1995;1:732-743.
54. D'Souza S, Alinauskas K, McCrea E, Goodyear C, Antel JP. Differential susceptibility of human CNS-derived cell populations to TNF-dependent and independent immune-mediated injury. J Neurosci 1995;15:7293-7300.
55. Nagata S. Apoptosis by death factor. Cell 1997;88:355-365.
56. Sipe KJ, Srisawasdi D, Dantzer R, Kelley KW, Weyhenmeyer JA. An endogenous 55 kDa TNF receptor mediates cell death in a neural cell line. Mol Brain Res 1996;38:222-232.
57. Bruce AJ, Boling W, Kindy MS, et al. Altered neuronal and microglial responses to excitotoxic and ischemic brain injury in mice lacking TNF receptors. Nature Med 1996;2:788-794.
58. Bhat RV, DiRocco R, Marcy VR, et al. Increased expression of IL-1b converting enzyme in hippocampus after ischemia: selective localization in microglia. J Neurosci 1996;16:4146-4154.
59. Bunone G, Mariotti A, Compagni A, Morandi E, Della Valle G. Induction of apoptosis by p75 neurotrophin receptor in human neuroblastoma cells. Oncogene 1997;14:1463-1470.
60. Casaccia-Bonnefil P, Aibel L, Chao MV. Central glial and neuronal populations display differential sensitivity to ceramide-dependent cell death. J Neurosci Res 1996;43:382-389.
61. Waxman SG, Kocsis JD. Spinal cord repair: progress towards a daunting goal. NEUROSCIENTIST 1997;3:263-269.
62. Becerra JL, Puckett WR, Hiester ED, et al. MR-pathologic comparisons of Wallerian degeneration in spinal cord injury. Am J Neuroradiol 1995;16:125-133.
63. Gage FH, Ray J, Fisher LJ. Isolation, characterization, and use of stem cells from the CNS. Annu Rev Neurosci 1995;18:159-192.
64. Frisen J, Johansson CB, Torok C, Lendahl U. Rapid, widespread, and long-lasting induction of nestin contributes to the generation of glial scar tissue after CNS injury. J Cell Biol 1995;131:453-464.
65. Bracken MB, Shepard MJ, Collins WF, et al. A randomized, controlled trial of methylprednisolone or naloxone in the treatment of acute spinal-cord injury. Results of the Second National Acute Spinal Cord Injury Study. N Engl J Med 1990;322:1405-1411.
66. Bracken MB, Shepard MJ, Holford TR, et al. Administration of methylprednisolone for 24 or 48 hours or tirilazad mesylate for 48 hours in the treatment of acute spinal cord injury. Results of the Third National Acute Spinal Cord Injury Randomized Controlled Trial. JAMA 1997;277:1597-1604.
67. Hara H, Friedlander RM, Gagliardini V, et al. Inhibition of interleukin 1 beta converting enzyme family proteases reduces ischemic and excitotoxic neural damage. Proc Natl Acad Sci U S A 1997;94:2007-2012.
68. Kroemer G. The proto-oncogene Bcl-2 and its role in regulating apoptosis. Nature Med 1997;3:614-620.