Squamous cell carcinoma of the tongue associated with cinnamon gum use: A case report

Head and Neck

Volumn 20, Issue 5, 1998, Pages 430-433

  Westra, William H ^a,b   McMurray, J Scott ^b   Califano, Joseph ^b   Flint, Paul W ^b   Corio, Russel L ^b  

^a JOHNS HOPKINS HOSPITAL   (United States)

^b DEPARTMENT OF PATHOLOGY   (United States)

Author keywords

Chewing gum; Cinnamon; Contact stomatitis; Oral cavity; Plasma cell gingivitis; Squamous cell carcinoma; Tongue

Indexed keywords

ALDEHYDE DERIVATIVE;

ADULT; ARTICLE; CANCER INFILTRATION; CASE REPORT; CHEMICAL CARCINOGENESIS; CHEWING GUM; CINNAMON; FEMALE; HISTOPATHOLOGY; HUMAN; LEUKOPLAKIA; MOUTH MUCOSA; PRIORITY JOURNAL; SQUAMOUS CELL CARCINOMA; TONGUE CARCINOMA; TUMOR BIOPSY;

ADULT; CARCINOMA, SQUAMOUS CELL; CHEWING GUM; CINNAMOMUM ZEYLANICUM; FEMALE; HUMANS; TONGUE NEOPLASMS;

EID: 0031835962     PISSN: 10433074     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0347(199808)20:5<430::AID-HED12>3.0.CO;2-K     Document Type: Article

References (12)

1. Blot W, McLaughlin J, Winn D, et al. Smoking and drinking in relation to oral and pharyngeal cancer. Cancer Res 1988;48:3282-3287.
2. Boffetta P, Mashberg A, Winkelmann R, Garfinkel L. Carcinogenic effect of tobacco smoking and alcohol drinking on anatomic sites of the oral cavity and oropharynx. Int J Cancer 1992;52:530-533.
3. Alien C, Blozis G. Oral mucosal reactions to cinnamon-flavored chewing gum. JADA 1988;116:664-667.
4. Mark AM: Cinnamon linked to oral sores, irritation. JADA 1199;126:1214 (Abstract).
5. Miller RL, Gould AR, Bernstein ML. Cinnamon-induced stomatits venenata: clinical and characteristic histopathologic features. Oral Surg Oral Med Oral Pathol 1992;73: 708-716.
6. Drake T, Maibach H. Allergic contact dermatits and stomatitis caused by a cinnamic aldehyde-flavored toothpaste. Arch Dermatol 1976;112:202-203.
7. Lamey P, Ress T, Forsyth A. Sensitivity reaction to the cinnamon-aldehyde component of toothpaste. Br Dent J 1990;168:115-118.
8. Mihail RC. Oral leukoplakia caused by cinnamon food allergy. J Otolaryngol 1992;21:366-367.
9. Nelville B, Damm D, Allen C, Bouquot J: Allergies and immunologic diseases. In Neville B, Damm D, Allen C, Bouquot J, eds. Oral & maxillofacial pathology. Philadelphia: W.B. Saunders Company, 1995:236-257.
10. Kerr D, McClatchey K, Regezi J. Allergic gingivostomatitis (due to chewing gum). J Periodontol 1971;42:709-712.
11. Counts JL, Goodman JL. Principles underlying dose selection for, and extrapolation from, the carcinogen bioassay: dose influences mechanism (review). Regulatory Toxicol Pharmacol 1995;21:418-421.
12. Conolly RB. Cancer and non-cancer risk assessment: not so different if you consider mechanisms (review). Toxicology 1995;102:179-188.