Molecular origin of the L-type Ca2+ current of skeletal muscle myotubes selectively deficient in dihydropyridine receptor β(1a) subunit

Biophysical Journal

Volumn 75, Issue 1, 1998, Pages 207-217

  Strube, Caroline ^a,b   Beurg, Maryline ^a   Sukhareva, Manana ^a   Ahern, Chris A ^a   Powell, Jeanne A ^c   Powers, Patricia A ^d   Gregg, Ronald G ^e   Coronado, Roberto ^a,d  

^a UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^b UNIVERSITÉ LYON 1   (France)

^c SMITH COLLEGE   (United States)

^d UNIVERSITY OF WISCONSIN MADISON   (United States)

^e UNIVERSITY OF LOUISVILLE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM CHANNEL; CALCIUM ION; DIHYDROPYRIDINE; RECEPTOR SUBUNIT;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CALCIUM CURRENT; CELL LABELING; CHANNEL GATING; CONTROLLED STUDY; CURVE FITTING; IMMUNOFLUORESCENCE; MOUSE; MYOTUBE; NONHUMAN; RECEPTOR DENSITY; SKELETAL MUSCLE; VOLTAGE CLAMP;

EID: 0031834133     PISSN: 00063495     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-3495(98)77507-1     Document Type: Article

References (47)

1. Adams, B. A., and K. G. Beam. 1989. A novel calcium current in dysgenic skeletal muscle. J. Gen. Physiol. 94:429-444.
2. Adams, B. A., and K. G. Beam. 1991. Contraction of dysgenic skeletal muscle triggered by a potentiated, endogenous calcium current. J. Gen. Physiol. 97:687-696.
3. Adams, B. A., T. Tanabe, A. Mikami, S. Numa, and K. G. Beam. 1990. Intramembrane charge movement restored in dysgenic skeletal muscle by injection of dihydropyridine receptor cDNAs. Nature. 346:569-572.
4. Bean, B. P., M. C. Nowycky, and R. W. Tsien. 1984. Beta-Adrenergic modulation of calcium channels in frog ventricular heart cells. Nature. 307:371-375.
5. 1 cDNA. Biophys. J. 73:807-818.
6. Bourinet, E., G. W. Zamponi, A. Stea, T. W. Soong, B. A. Lewis, L. P. Jones, D. T. Yue, and T. P. Snutch. 1996. The a1E calcium channel exihibits permeation properties similat to low-voltage-activated calcium channels. J. Neurosci. 16:4983-4993.
7. 2+ conductance in myotubes from mutant mice with "muscular dysgenesis." Pflugers Arch. Eur. J. Physiol. 414:410-415.
8. Bulteau, L., M. Cogne, C. Cognard, and G. Raymond. 1977. Reversal of the relative expression of cardiac and skeletal alpha 1 subunit isoforms of the L-type calcium channel during in vitro myogenesis. Pflugers Arch. Eur. J. Physiol. 433:376-378.
9. Castellano, A., X. Wei, L. Birnbaumer, and E. Perez-Reyes. 1993. Cloning and expression of a third calcium channel beta subunit. J. Biol. Chem. 268:3450-3455.
10. Chaudhari, N. 1992. A single nucleotide deletion in the skeletal muscle-specific calcium channel transcript of muscular dysgenesis (mdg) mice. J. Biol. Chem. 267:25636-25639.
11. Chaudhari, N., and K. G. Beam. 1993. mRNA for cardiac calcium channel is expressed during development of skeletal muscle. Dev. Biol. 155: 507-515.
12. 2+ channels. J. Biol. Chem. 270:30036-30044.
13. Conti, F., L. J. De Felice, and E. Wanke. 1975. Potassium and sodium current noise in the membrane of the squid giant axon. J. Physiol. (Lond.). 248:45-82.
14. Dirksen, R. T., and K. G. Beam. 1995. Single calcium channel behavior in native skeletal muscle. J. Gen. Physiol. 105:227-247.
15. 2+ channel unitary conductance. Biophysic. J. 72:A245.
16. Flucher, B. E., J. L. Phillips, and J. A. Powell. 1991. Dihydropyridine receptor alpha subunits in normal and dysgenic muscle in vitro: expression of alpha-1 is required for proper tragetting and distribution of alpha-2. J. Cell Biol. 115:1345-1356.
17. Garcia-Martinez, J., and K. G. Beam. 1994. Measurement of calcium transients and slow calcium current in myotubes. J. Gen. Physiol. 103:107-123.
18. Garcia-Martinez, J., T. Tanabe, and K. G. Beam. 1994. Relationship of calcium transients to calcium currents and charge movements in myotubes expressing skeletal and cardiac dihydropyridine receptors. J. Gen. Physiol. 103:125-147.
19. Gregg, R. G., A. Messing, C. Strube, M. Beurg, R. Moss, M. Behan, M. Sukhareva, S. Haynes, J. A. Powell, R. Coronado, and P. A. Powers. 1996. Absence of the beta subunit (cchb1) of the skeletal muscle dihydropyridine receptor alters expression of the alpha(1) subunit and eliminates excitation-contraction coupling. Proc. Natl. Acad. Sci. USA. 93:13961-13966.
20. Heinemann, S. H., and F. Conti. 1992. Nonstationary analysis and application to patch clamp recordings. Methods Enzymol. 207:131-148.
21. Hullin, R., D. Singer-Lahat, M. Freichel, M. Biel, N. Dascal, F. Hofmann, and V. Flockerzi. 1992. Calcium channel beta subunit heterogeneity: functional expression of cloned cDNA from heart, aorta and brain. EMBO J. 11:885-890.
22. Itagaki, K., W. J. Koch, I. Bodi, U. Klockner, D. F. Slish, and A. Schwartz. 1992. Native-type DHP-sensitive calcium channel currents are produced by cloned aortic smooth muscle and cardiac alpha1 subunits expressed in Xenopus laevis oocytes and are regulated by alpha2 and beta subunits. FEBS Lett. 297:221-225.
23. Kamp, T. J., M. T. Perez-Garcia, and E. Marban. 1996. Enhancement of ionic current and charge movement by coexpression of calcium channel betalA subunit with alpha1C subunit in a human embryonic kidney cell line. J. Physiol. (Lond.). 492:89-96.
24. 1 subunit of the dihydropyridine receptor in mice with muscular dysgenesis. J. Biol. Chem. 264:1345-1348.
25. 2+ channel. Biophys. J. 63:1421-1424.
26. 2+ channel alphal subunit as expressed in mouse L cells. FEBS Lett. 315:167-172.
27. Neher, E., and C. F. Stevens. 1975. Conductance fluctuations and ionic pores in membranes. Annu. Rev. Biophys. Bioeng. 6:345-381.
28. Nishimura, S., H. Takeshima, F. Hofmann, V. Flockerzi, and K. Imoto. 1993. Requirement of the calcium channel beat subunit for functional conformation. FEBS Lett. 324:283-286.
29. 2+ channels. J. Gen. Physiol. 108:143-155.
30. Ohlendieck, K., F. N. Briggs, K. F. Lee, A. W. Wechsler, and K. P. Campbell. 1991. Analysis of excitation-contraction coupling components in chronically stimulated canine skeletal muscle. Eur. J. Biochem. 202:739-747.
31. Pereon, Y., J. Navarro, and P. T. Palade. 1997. Expression of the dihydropyridine receptor alpha-1 sububit isoforms in adult rat and mouse skeletal muscle. Biophys. J. 72:A149.
32. Perez-Garcia, M. T., T. J. Kamp, and E. Marban. 1995. Functional properties of cardiac L-type calcium channels transiently expressed in HEK293 cells. Role of alpha 1 and beta subunits. J. Gen. Physiol. 105:289-306.
33. Perez-Reyes, E., A. Castellano, H. S. Kim, P. Bertrand, E. Baggstrom, A. E. Lacerda, X. Wei, and L. Birnbaumer. 1992. Cloning and expression of a cardiac/brain beta subunit of the L-type calcium channel. J. Biol. Chem. 267:1792-1797.
34. Shimahara, T., and R. Bournaud. 1991. Barium current in developing skeletal muscle cells of normal and mutant mice foetuses with "muscular dysgenesis." Cell Calcium. 12:727-733.
35. Sigworth, F. J. 1980. The variance of sodium current fluctuations at the node of Ranvier. J. Physiol. (Lond.). 307:97-129.
36. Singer, D., M. Biel, I. Lotan, V. Flockerzi, F. Hofmann, and N. Dascal. 1991. The role of the subunits in the function of calcium channel. Science. 253:1553-1557.
37. 2+ transients in skeletal muscle deficient in dihydropyridine receptor beta 1 subunit. Biophys. J. 71:2531-2543.
38. 2+ current of beta-1 null mytubes is not a dysgenic current. Biophys. J. 72:A147.
39. Tanabe, T., B. A. Adams, S. Numa, and K. G. Beam. 1991. Repeat I of the dihydropyridine receptor is critical in determining calcium channel activation kinetics. Nature. 352:800-803.
40. Tanabe, T., K. G. Beam, B. A. Adams, T. Niidome, and S. Numa. 1990a. Regions of skeletal muscle dihydropiridine receptor critical for excitation-contraction coupling. Nature. 346:567-569.
41. Tanabe, T., K. G. Beam, J. A. Powell, and S. Numa. 1988. Restoration of excitation-contraction coupling and slow calcium current in dysgenic muscle by dihydropyridine receptor complementary DNA. Nature. 336: 134-139.
42. Tanabe, T., A. Mikami, S. Numa, and K. G. Beam. 1990b. Cardiac-type excitation-contraction coupling in dysgenic skeletal muscle injected with cardiac dihydropyridine receptor cDNA. Nature. 344:451-453.
43. Tsien, R. W., B. P. Bean, P. Hess, J. B. Lansman, B. Nilius, and M. C. Nowycky. 1986. Mechanism of calcium channel modulation by β-adrenergic agents and dihydropyridine calcium agonists. J. Mol. Cell. Cardiol. 18:691-710.
44. Varadi, G., P. Lory, D. Schultz, M. Varadi, and A. Schwartz. 1991. Acceleration of activation and inactivation by the beta subunit of the skeletal muscle calcium channel. Nature. 352:159-162.
45. 2+ channels do not overcome the E-C coupling defect in immortalized dysgenic muscle cells: evidence for a missing link. FEBS Lett. 386:405-410.
46. 2+ channel alppha1 subunit by skeletal muscle beta and gamma subunits. J. Biol. Chem. 266:21943-21947.
47. 2+ channels. Nature. 366:158-161.