Antithrombin and ischemia/reperfusion

Blood Coagulation and Fibrinolysis

Volumn 9, Issue SUPPL.. 2, 1998, Pages

  Woodman, Richard C ^a,b   Ostrovsky, Lena ^a   Teoh, Diane ^a   Payne, Derrice ^a   Poon, Man Chiu ^a,b   Kubes, Paul ^a  

^a UNIVERSITY OF CALGARY   (Canada)

^b UNIVERSITY OF CALGARY   (Canada)

Author keywords

Antithrombin; Endothelial inflammation; Ischemia reperfusion; Microvascular; Neutrophil; Selectins; Thrombin

Indexed keywords

ANTITHROMBIN; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; PADGEM PROTEIN; THROMBIN;

BLOOD CLOTTING; CELL INTERACTION; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; INFLAMMATION; NEUTROPHIL; PRIORITY JOURNAL; REPERFUSION INJURY; REVIEW; THROMBOSIS;

ANIMALS; ANTITHROMBIN III; CELL ADHESION; ENDOTHELIUM, VASCULAR; HUMANS; ISCHEMIA; NEUTROPHILS; REPERFUSION INJURY; THROMBIN;

EID: 0031833254     PISSN: 09575235     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (38)

1. Kubes P, Jutila M, Payne D. Therapeutic potential of inhibiting leukocyte rolling in ischemia/reperfusion. J Clin Invest 1995; 95: 2510-2519.
2. Weyrich AS, Ma X, Lefer DJ, Albertine KH, Lefer AM. In-vivo neutralization of P-selectin protects feline heart and endothelium in myocardial ischemia and reperfusion injury. J Clin Invest 1993; 91: 2620-2629.
3. Ma X, Weyrich AS, Lefer DJ, Buerke M, Albertine KE, Kishimoto TK, Lefer AM. Monoclonal antibody to L-selectin attenuates neutrophil accumulation and protects ischemic reperfused cat myocardium. Circulation 1993; 88: 649-658.
4. Von Andrian UH, Chambers JD, McEvoy LM, Bargatze RF, Arfors KE, Butcher EC. Two-step model of leukocyte-endothelial cell interaction in inflammation: distinct roles for LECAM-1 and the leukocyte 2 integrins in vivo. Proc Natl Acad Sci USA 1991; 88: 7538-7542.
5. Springer TA. Adhesion receptors of the immune system. Nature 1990; 346: 425-434.
6. Ma X, Tsao PS, Lefer AM. Antibody to CD-18 exerts endothelial and cardiac protective effects in myocardial ischemia and reperfusion. J Clin Invest 1991; 88: 1237-1243.
7. Romson JL, Hook BG, Kunkel SL, Abrams GD, Schork A, Lucchesi BR. Reduction in the extent of ischemic myocardial injury by neutrophil depletion in the dog. Circulation 1983;67:1016-1023.
8. Granger DN. Role of xanthine oxidase and granulocytes in ischemia-reperfusion injury. Am J Physiol 1988;255:H1269-H1275.
9. Hernandez LA, Grisham MB, Twohig B, Arfors KE, Harlan JM, Granger DN. Role of neutrophils in ischemia-reperfusion-induced microvascular injury. Am J Physiol 1987; 253: H699-H703.
10. Winn RK, Liggiitt D, Vedder NB, Paulson JC, Harlan JM. Anti-P-selectin monoclonal antibody attenuates reperfusion injury to the rabbit ear. J Clin Invest 1993; 92: 2042-2047.
11. Grisham MB, Hernandez LA, Granger DN. Adenosine inhibits ischemia-reperfusion-induced leukocyte adherence and extravasation. Am J Physiol 1989; 257: H1334-H1339.
12. Kubes P, Kurose I, Granger DN. NO donors prevent integrin-induced leukocyte adhesion, but not P-selectin-dependent rolling in post-ischemic venules. Am J Physiol 1994; 267: H931-H937.
13. Mori E, del Zoppo GJ, Chambers JD, Copeland BR, Arfors KE. Inhibition of polymorphonuclear leukocyte adherence suppresses no-reflow after focal cerebral ischemia. Stroke 1992; 23: 712-718.
14. Korthuis RJ, Grisham MB, Granger DN. Leukocyte depletion attenuates vascular injury in postischemic skeletal muscle. Am J Physiol 1988; 254: H823-H827.
15. Jaeschke H, Farhood A, Smith CW. Neutrophils contribute to ischemia/reperfusion injury in rat liver in vivo. FASEB J 1990; 4: 3355-3359.
16. Welbourn CRB, Goldman G, Paterson IS, Valeri CR, Shepro D, Hechtman HB. Neutrophil elastase and oxygen radicals: synergism in lung injury after hindlimb ischemia. Am J Physiol 1991; 260: H1852-H1856.
17. Lorant DE, Patel KD, McIntyre TM, McEver RP, Prescott SM, Zimmerman GA. Coexpression of GMP-140 and PAF by endothelium stimulated by histamine or thrombin: a juxtacrine system for adhesion and activation of neutrophils. J Cell Biol 1991; 115: 223-234.
18. Geng J-G, Bevilacqua MP, Moore KL, McIntyre TM, Prescott SM, Kim JM, et al. Rapid neutrophil adhesion to activated endothelium mediated by GMP-140. Nature 1990; 343: 757-760.
19. Zimmerman GA, McIntyre TM, Prescott SM. Thrombin stimulates neutrophil adherence by an endothelial cell-dependent mechanism: characterization of the response and relationship to platelet-activating factor synthesis. Ann NY Acad Sci 1986; 485: 349-368.
20. Shankar R, de la Motte CA, Poptic EJ, DiCorleto PE. Thrombin receptor-activating peptides differentially stimulate platelet-derived growth factor production, monocytic cell adhesion, and E-selectin expression in human umbilical vein endothelial cells. J Biol Chem 1994; 269: 13936-13941.
21. Sugama Y, Tiruppathi C, Janakidevi K, Andersen TT, Fenton JW, Malik AB. Thrombin-induced expression of endothelial P-selectin and intercellular adhesion molecule-1: a mechanism for stabilizing neutrophil adhesion. J Cell Biol 1992; 119: 935-944.
22. Zimmerman GA, McIntyre TM, Prescott SM. Thrombin stimulates the adherence of neutrophils to human endothelial cells in vitro. J Clin Invest 1985; 76: 2235-2246.
23. Granger DN, Rutili G, McCord JM. Superoxide radicals in feline intestinal ischemia. Gastroenterology 1981; 81: 22-29.
24. Lehr HA, Guhlmann A, Nolte D, Keppler D, Messmer K. Leukotrienes as mediators in ischemia-reperfusion injury in a microcirculation model in the hamster. J Clin Invest 1991;87:2036-2041.
25. Granger DN, Benoit JN, Suzuki M, Grisham MB. Leukocyte adherence to venular endothelium during ischemia-reperfusion. Am J Physiol 1989;257:G683-G688.
26. Suzuki M, Grisham MB, Granger DN. Leukocyte-endothelial cell adhesive interactions: role of xanthine oxidase-derived oxidants. J Leukoc Biol 1991;50:488-494.
27. Ostrovsky L, Woodman RC, Payne D, Teoh D, Kubes P. Antithrombin III prevents and rapidly reverses leukocyte recruitment in ischemia/reperfusion. Circulation 1997;96:2302-2310.
28. Emerson TE Jr. Antithrombin III replacement in animal models of acquired antithrombin III deficiency. Blood Coagul Fibrinol 1994;5(suppl 1):S37-S45.
29. 4-integrin, P-selectin, and E-selectin in an allergic model of inflammation. J Exp Med 1997;185:1077-1087.
30. Bahou WF, Coller BS, Potter CL, Norton KJ, Kutok JL, Goligorsky MS. The thrombin receptor extracellular domain contains sites crucial for peptide ligand-induced activation. J Clin Invest 1993; 91: 1405-1413
31. Vu T-K, Hung DT, Wheaton VI, Coughlin SR. Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation. Cell 1991; 64: 1057-1068.
32. Hattori R, Hamilton KK, Fugate RD, McEver RP, Sims PJ. Stimulated secretion of endothelial von Willebrand factor is accompanied by rapid redistribution to the cell surface of the intracellular granule membrane protein GMP-140. J Biol Chem 1989; 264: 7768-7771.
33. Green SA, Setiadi H, McEver RP, Kelly RB. The cytoplasmic domain of P-selectin contains a sorting determinant that mediates rapid degradation in lysosomes. J Cell Biol 1994; 124: 435-448.
34. Kanwar S, Woodman RC, Poon M-C, Murohara T, Lefer AM, Davenpeck KL, Kubes P. Desmopressin induces endothelial P-selectin expression and leukocyte rolling in postcapillary venules. Blood 1995; 86: 2760-2766.
35. Lawrence MB, Springer TA. Leukocytes roll on a selectin at physiologic flow rates: distinction from and prerequisite for adhesion through integrins. Cell 1991; 65: 859-873.
36. Shankar R, De la Motte CA, Poptic EJ, Dicorleo PE. Thrombin receptor-activating peptides differentially stimulate platelet-derived growth factor production, monocytic cell adhesion, and E-selectin expression in human umbilical vein endothelial cells. J Biol Chem 1994; 269: 13936-13941.
37. Ostrovsky L, Teoh D, Woodman RC, Kubes P. Thrombin-induced endothelial-leukocyte interactions [abstract]. FASEB J 1997;11: A302.
38. MacDonald BR, Chastain M, Shuman RT, Smith G, Hahn RA. Salvage of reperfused ischemia myocardium by LY293435 ILY, a thrombin inhibitor, in a non-thrombotic canine model [abstract]. FASEB J 1995; 9: A3611.