Electrophysical properties, synaptic transmission and neuromodulation in serotonergic caudal raphe neurons

Clinical and Experimental Pharmacology and Physiology

Volumn 25, Issue 6, 1998, Pages 468-473

  Li, Yu Wen ^a,b   Bayliss, Douglas A ^a  

^a UNIVERSITY OF VIRGINIA   (United States)

^b DUPONT COMPANY   (United States)

Author keywords

5 Hydroxytryptamine; Electrophysiology; Glutamatergic; Inwardly rectifying potassium current; Synaptic transmission

Indexed keywords

SEROTONIN; SEROTONIN RECEPTOR;

AUTOREGULATION; CARDIOVASCULAR AUTOREGULATION; CONFERENCE PAPER; EXCITATORY POSTSYNAPTIC POTENTIAL; FEEDBACK SYSTEM; IMMUNOHISTOCHEMISTRY; NEUROMODULATION; POTASSIUM CURRENT; SEROTONINERGIC NERVE CELL; STEADY STATE; SYNAPTIC TRANSMISSION;

EID: 0031832903     PISSN: 03051870     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1440-1681.1998.tb02237.x     Document Type: Conference Paper

References (14)

1. Jacobs BL, Azmitia EC. Structure and function of the brain serotonin system. Physiol. Rev. 1992; 72: 165-229.
2. Pickering AE, Spanswick D, Logan SD. 5-Hydroxytryptamine evokes depolarizations and membrane potential oscillations in rat sympathetic preganglionic neurons. J. Physiol. 1994; 480: 109-21.
3. Veasey SC, Fornal CA, Metzler CW, Jacobs BL. Response of serotonergic caudal raphe neurons in relation to specific motor activities in freely moving cats. J. Neurosci. 1995; 15: 5346-59.
4. Dampney RAL. The subretrofacial vasomotor nucleus: Anatomical, chemical and pharmacological properties and role in cardiovascular regulation. Progr. Neurobiol. 1994; 42: 197-228.
5. Clement ME, McCall RB. Studies on the site and mechanism of the sympatholytic action of 8-OH DPAT. Brain Res. 1990; 525: 232-41.
6. McCall RB, Clement ME. Identification of serotonergic and sympathetic neurons in medullary raphe neurons. Brain Res. 1989; 477: 172-82.
7. Bayliss DA, Li YW, Talley EM. Effects of serotonin on caudal raphe neurons: Activation of an inwardly rectifying potassium conductance. J. Neurophysiol. 1997; 77: 1349-61.
8. Li YW, Bayliss DA. Presynaptic inhibition by receptors of glutamatergic synaptic inputs on the serotonergic caudal raphe neurones in rat. J. Neurophysiol. 1998 (in press).
9. Katz B. The Release of Neural Transmitter Substances. Thomas, Springfield. 1969.
10. Thompson SM, Capogna M, Scanziani M. Presynaptic inhibition in the hippocampus. Trends Neurosci. 1993; 16: 222-7.
11. Bayliss DA, Li YW, Talley EM. Effects of serotonin on caudal raphe neurons: Inhibition of N- and P/Q-type calcium channels and the after-hyperpolarization. J. Neurophysiol. 1997; 77: 1362-74.
12. Pan ZZ, Wessendorf MW, William JT. Modulation by serotonin of the neurons in rat nucleus raphe magnus in vitro. Neuroscience 1993; 54: 421-9.
13. 1A receptors on dorsal raphe neurons of the adult rat. J. Physiol. 1993; 469: 407-26.
14. Fornal CA, Metzler CW, Gallegos RA, Veasey SC, McCreary AC, Jacobs BL. WAY-100635, a potent and selective 5-hydroxytryptamine IA antagonist, increases serotonergic neuronal activity in behaving cats: Comparison with (S)-WAY-100135. J. Pharmacol. Exp. Ther. 1996; 278: 752-62.