In vitro evaluation of the cytotoxic, hemolytic and clastogenic activities of Rhizostoma pulmo toxin(s)

Toxicon

Volumn 36, Issue 6, 1998, Pages 933-936

  Allavena, A ^a   Mariottini, G L ^b   Carli, A M ^b   Contini, S ^b   Martelli, A ^a  

^a UNIVERSITY OF GENOA   (Italy)

^b UNIVERSITY OF GENOA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOTOXIC AGENT;

ANIMAL TISSUE; ARTICLE; CELL CULTURE; ENZYME ACTIVATION; ENZYME ACTIVITY; HEMOLYSIS; HUMAN; HUMAN CELL; LYMPHOCYTE CULTURE; MAMMAL; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS;

ANIMALS; CELL LINE; ERYTHROCYTES; FEMALE; HUMANS; LYMPHOCYTES; MARINE TOXINS; MICRONUCLEUS TESTS; SCYPHOZOA;

EID: 0031832561     PISSN: 00410101     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0041-0101(97)00171-2     Document Type: Article

References (11)

1. Babich H., Borenfreund E. Structure-activity relationship (SAR) models established in vitro with the neutral red cytotoxicity assay. Toxicology in Vitro. 1:1987;3-9.
2. Bailey, N. T. J. (1959) Statistical Methods in Biology. The English Universities Press, London.
3. Cariello L., Romano G., Spagnuolo A., Zanetti L. Isolation and partial characterization of rhizolysin, a high molecular weight protein with hemolytic activity, from the jellyfish Rhizostoma Pulmo. Toxicon. 26:1988;1057-1065.
4. Carli A., Bussotti S., Mariottini G. L., Robbiano L. Toxicity of jellyfish and sea-anemone venoms on cultured V79 cells. Toxicon. 34:1996;496-500.
5. Endean R., Noble M. Toxic material from tentacles of the cubomedusan Chironex fleckeri. Toxicon. 9:1971;255-264.
6. Fenech M. The cytokinesis-block micronucleus technique: a detailed description of the method and its application to genotoxicity studies in human population. Mutation Res. 285:1993;35-44.
7. Freeman S. E., Turner R. J. A pharmacological study of the toxin of a Cnidarian, Chironex fleckeri Southcott. British Journal Pharmacology. 35:1969;510-520.
8. Macek P., Lebez D. Kinetics of hemolysis induced by equinatoxin, a cytolytic toxin from the sea-anemone Actinia equina. Effect of some ions and pH. Toxicon. 19:1981;233-240.
9. Mariscal, R. N. (1974) Nematocysts. In Coelenterate Biology. Reviews and new perspectives. ed. L. Muscatine and H. M. Lenhoff, pp. 129-178. Academic Press, New York.
10. Toom P. M., Chan D. S. Preliminary studies of nematocysts from the jellyfish Stomalophus meleagris. Toxicon. 10:1972;605-612.
11. Wittle L. W., Scura E. D., Middlebrook R. E. Stinging coral (Millepora tenera) toxin: a comparison of crude extracts with isolated nematocyst extracts. Toxicon. 12:1974;481-486.