On the mechanism of plasmin-induced aggregation of human platelets: Implication of secreted von Willebrand factor

Thrombosis and Haemostasis

Volumn 79, Issue 6, 1998, Pages 1191-1198

  Rabhi Sabile, S ^a   De Romeuf, C ^b   Pidard, D ^a,c  

^a SAINT LOUIS HOSPITAL   (France)

^b Laboratoire Francais du Fractionnement et des Biotechnologies   (France)

^c INSTITUT PASTEUR   (France)

Author keywords

[No Author keywords available]

Indexed keywords

FIBRINOGEN; FIBRONECTIN; PLASMIN; THROMBOSPONDIN; VON WILLEBRAND FACTOR;

ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN CELL; IMMUNOBLOTTING; MOLECULAR WEIGHT; PRIORITY JOURNAL; PROTEIN DEGRADATION; THROMBOCYTE AGGREGATION; THROMBOCYTE MEMBRANE; VON WILLEBRAND DISEASE;

EID: 0031832409     PISSN: 03406245     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-0037-1615039     Document Type: Article

References (10)

1. Anglès-Cano E. Overview on fibrinolysis: plasminogen activation pathways on fibrin and cell surfaces. Chem Phys Lipids 1994; 67/68: 353-62.
2. Collen D, Lijnen HR. Basic and clinical aspects of fibrinolysis and thrombolysis. Blood 1991; 78: 3114-24.
3. Coller BS. Platelets in cardiovascular thrombosis and thrombolysis. In: The Heart and Cardiovascular System. 2nd edition. Fozzard HA, Haber E, Jennings RB, Katz AM, Morgan HE, eds. Raven Press, New York 1992; pp 219-73.
4. Pasche B, Ouimet H, Francis S, Loscalzo J. Structural changes in platelet glycoprotein IIb/IIIa by plasmin: determinants and functional consequences. Blood 1994; 83: 404-14.
5. Hoffmann JJML, Janssen WCM. Interactions between thrombolytic agents and platelets: effects of plasmin on platelet glycoproteins Ib and IIb/IIIa. Thromb Res 1992; 67: 711-9.
6. Federici AB, Berkowitz SD, Zimmerman TS, Mannucci PM. Proteolysis of von Willebrand factor after thrombolytic therapy in patients with acute myocardial infarction. Blood 1992; 79: 38-44.
7. Schafer AI, Maas AK, Ware JA, Johnson PC, Rittenhouse SE, Salzman E.W. Platelet protein phosphorylation, elevation of cytosolic calcium, and inositol phospholipid breakdown in platelet activation induced by plasmin. J Clin Invest 1986; 78: 73-9.
8. Penny WF, Ware JA. Platelet activation and subsequent inhibition by plasmin and recombinant tissue-type plasminogen activator. Blood 1992; 79: 91-8.
9. Schafer AI, Adelman B. Plasmin inhibition of platelet function and of arachidonic acid metabolism. J Clin Invest 1985; 75: 456-61.
10. Nakamura K, Kimura M, Fenton II JW, Andersen TT, Aviv A. Duality of plasmin effect on cytosolic free calcium in human platelets. Am J Physiol 1995; 268: C958-67.