Human pancreatic secretory tripsin inhibitor. Distribution, actions and possible role in mucosal integrity and repair

Digestion

Volumn 59, Issue 3, 1998, Pages 167-174

  Marchbank, T ^a   Freeman, T C ^a   Playford, R J ^a  

^a UNIVERSITY HOSPITALS OF LEICESTER NHS TRUST   (United Kingdom)

Author keywords

Cholecystokinin; Mucosal integrity; Mucus; Ulceration

Indexed keywords

APROTININ; EPIDERMAL GROWTH FACTOR RECEPTOR; PROTEINASE;

BREAST; CELL LINE; CELL MIGRATION; CELL PROLIFERATION; COLON; DIGESTION; ENZYME REGULATION; GASTROINTESTINAL TRACT; HEALING; KIDNEY; LUNG; MUCOSA; MUCOUS CELL; MUCUS; PANCREAS; PRIORITY JOURNAL; PROTEIN LOCALIZATION; REVIEW; STOMACH; TISSUE REPAIR;

ANIMALS; GASTRIC MUCOSA; HUMANS; INTESTINAL MUCOSA; RECEPTOR, EPIDERMAL GROWTH FACTOR; TRYPSIN INHIBITOR, KAZAL PANCREATIC;

EID: 0031831562     PISSN: 00122823     EISSN: None     Source Type: Journal    
DOI: 10.1159/000007485     Document Type: Review

References (34)

1. Bode W, Huber R: Natural protein proteinase inhibitors and their interaction with proteinases. Eur J Biochem 1992;204:433-451.
2. Fritz H, Kruck J, Russe I, Liebich HG: Immunofluorescence studies indicate that the basic trypsin-kallikrein-inhibitor of bovine organs (Trasylol) originates from mast cells. Hoppe Seylers Z Physiol Chem 1979;360:437-444.
3. Kazal LA, Spicer DS, Brahinsky RA: Isolation of a crystalline trypsin inhibitor-anticoagulant protein from the pancreas. J Am Chem Soc 1948;70:304-340.
4. Laskowski M, Wu FC: Temporary inhibition of trypsin. J Biol Chem. 1953;204:797-805.
5. Bartelt DC, Shapanka R, Green LJ: The primary structure of the human pancreatic secretory trypsin inhibitor. Arch Biochem Biophys 1977; 179:189-199.
6. Huhtala ML, Kahanpaa K, Seppala M, Halila H, Stenman UH: Excretion of a tumour associated trypsin inhibitor (TATI) in urine of patients with gynaecological malignancy. Int J Cancer 1983;31:711-714.
7. Horii A, Kobayashi T, Tomita N, Yamamoto T, Fukushige S, Murotsu T, Ogawa M, Mori T, Matsubara K: Primary structure of human secretory trypsin inhibitor (PSTI) gene. Biochem Biophys Res Commun 1987;149:635-641.
8. Shibata T, Ogawa M, Matsuda K, Miyauchi K, Yamamoto T, Mori T: Purification and characterisation of pancreatic secretory trypsin inhibitor in human gastric mucosa. Clin Chim Acta 1986;159:27-36.
9. Freeman TC, Playford RJ, Quinn K, Beardshall K, Calam J: Pancreatic secretory trypsin inhibitor in gastrointestinal mucosa and gastric juice. Gut 1990;31:1318-1323.
10. Shibata T, Ogawa M, Takata N: Distribution of pancreatic secretory trypsin inhibitor in various human tissues and its inactivation in the gastric mucosa. Res Commun Pathol Pharmacol 1987;55:243-248.
11. Marchbank T, Chinery R, Hanby AM, Poulsom R, Elia G, Playford RJ: Distribution and expression of pancreatic secretory trypsin inhibitor and its possible role in epithelial restitution. Am J Pathol 1996;148:715-722.
12. Pezzilli R, Billi P, Plate L, Barakat B, Bongiovanni F, Miglioli M: Human pancreatic secretory inhibitor in the assessment of the severity of acute pancreatitis. J Clin Gastroenterol 1994;19:112-117.
13. Marks WH, Ohlsson K: Elimination of pancreatic secretory trypsin inhibitor from the circulation. Scand J Gastroenterol 1983;18:955-959.
14. Halila H, Huhtala ML, Schroder T, Kiviluoto T, Stenman UH: Pancreatic secretory trypsin inhibitor-like immunoreactivity in pancreatectomized patients. Clin Chim Acta 1985;153: 209-216.
15. Playford RJ, Batten JJ, Freeman TC, Beardshall K, Vesey D, Fenn GC, Baron JH, Calam J: Gastric output of pancreatic secretory trypsin inhibitor is increased by misoprostol. Gut 1991;32:1396-1400.
16. Fukuoka SI, Scheele G: Complementary nucleotide sequence for monitor peptide, a novel cholecystokinin-releasing peptide in the rat. Nucl Acids Res 1989;17:10111.
17. Owyang C, May D, Louie DS: Trypsin suppression of pancreatic enzyme secretion. Gastroenterology 1986;91:637-643.
18. Owyang C, Louie DS, Tatum D: Feedback regulation of pancreatic enzyme secretion. J Clin Invest 1986;77:2042-2047.
19. Playford RJ, Freeman TC, Calam J: Is human pancreatic secretory trypsin inhibitor a CCK-releasing peptide in man? Regul Pept 1992;40: 228.
20. Miyasaka K, Guan DF, Liddle RA, Green GM: Feedback regulation by trypsin: Evidence for intraluminal CCK-releasing peptide. Am J Physiol 1989;257:G175-G181.
21. Allen A, Hutton DA, Leonard AJ, Pearson JP, Sellers LA: The role of mucus in the protection of the gastroduodenal mucosa. Scand J Gastroenterol 1986;(suppl 125):71-78.
22. Molinari F, Parodi MC, De Angelis P, Cheli R: Gastric mucus secretion in chronic gastritis. Scand J Gastroenterol 1984;19(suppl 92):167-171.
23. Bell AE, Sellers A, Allen A, Cuncliffe WJ, Morris ER, Ross-Murphy SB: Properties of gastric and duodenal mucus: Effect of proteolysis, disulphide reduction, bile, acid, ethanol, and hypertonicity on mucus gel structure. Gastroenterology 1985;88:269-280.
24. Playford RJ, Hanby AM, Quinn C, Calam J: Influence of inflammation and atrophy on pancreatic secretory trypsin inhibitor levels within the gastric mucosa. Gastroenterology 1994; 106:735-741.
25. Senda S, Fujiyama Y, Bamba T, Hosada S: Treatment of ulcerative colitis with camostat mesilate, a serine protease inhibitor. Intern Med 1993;32:350-354.
26. Playford RJ, Hanby AM, Patel K, Calam J: Influence of inflammatory bowel disease on the distribution and concentration of pancreatic secretory trypsin inhibitor within the colon. Am J Path 1995;146:310-316.
27. Scheving LA: Primary amino acid sequence similarity between human epidermal growth factor-urogastrone, human pancreatic secretory trypsin inhibitor and members of the secretin family. Arch Biochem Biophys 1983;226: 411-413.
28. Ogawa M, Tsushima T, Ohba Y: Stimulation of DNA synthesis in human fibroblasts by human pancreatic secretory trypsin inhibitor. Res Commun Chem Pathol Pharmacol 1985;50: 155-158.
29. McKeenan WL, Sakagami Y, Hoshi H: Two apparent human endothelial cell growth factors from hepatoma cells are tumor-associated proteinase inhibitors. J Biol Chem 1986;261: 5378-5383.
30. Freeman TC, Curry BJ, Calam J, Woodburn J: Pancreatic secretory trypsin inhibitor stimulates the growth of pancreatic tumour cells. Gastroenterology 1990;99:1414-1420.
31. Fukuoka SI, Fushiki T, Kitagawa Y, Sugimoto EI: Competition of a growth stimulating-/cholecystokinin (CCK) releasing peptide (monitor peptide) with epidermal growth factor binding to 3T3 fibroblasts. Biochem Biophys Res Commun 1987;145:646-650.
32. Niinobu T, Murata A, Nishijima J, Mori T: Identification and characterisation of receptors specific for human pancreatic secretory trypsin inhibitor. J Exp Med 1990;172:1133-1142.
33. Silen W: Gastric mucosal defence and repair; in Johnson LR (ed): Physiology of the Gastrointestinal Tract, ed 2. New York, Raven, 1987, pp 1044-1069.
34. Poulsom R, Wright NA: Trefoil peptides: A newly recognised family of epithelial mucin-associated molecules. Am J Physiol 1993;265: G205-213.