Hepatocyte apoptosis and hepatic expression of transforming growth factor-β1 mRNA during involution of hyperplastic rat liver induced by hepatocyte growth factor

Journal of Gastroenterology and Hepatology (Australia)

Volumn 13, Issue 8, 1998, Pages 786-793

  Nagoshi, Sumiko ^a   Yasuda, Hisataka ^c   Suda, Jyun ^b   Yamanobe, Fumio ^b   Ohno, Akihiko ^a   Higashio, Kanji ^c   Fujiwara, Kenji ^b  

^a UNIVERSITY OF TOKYO   (Japan)

^b SAITAMA MEDICAL UNIVERSITY   (Japan)

^c SNOW BRAND MILK PRODUCTS CO LTD   (Japan)

Author keywords

Hepatocyte apoptosis; Hepatocyte growth factor

Indexed keywords

MESSENGER RNA; TRANSFORMING GROWTH FACTOR BETA1;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; ELECTRON MICROSCOPY; GROWTH REGULATION; LIVER CELL; LIVER HYPERPLASIA; MALE; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT;

EID: 0031830931     PISSN: 08159319     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1440-1746.1998.tb00734.x     Document Type: Article

References (46)

1. Schulte-Hermann R, Hoffmann V, Parzefall W, Kallenbach M, Gerhardt A, Schuppler J. Adaptive responses of rat liver to the gestagen and anti-androgen cyproterone acetate and other inducers. II. Induction of growth. Chem. Biol. Interact. 1980; 31: 287-300.
2. Schulte-Hermann R, Koransky W, Leberl C, Noack G. Hyperplasia and hypertrophy of rat liver induced by α-hexachlorocyclohexane and butylhydroxytoluene. Retention of the hyperplasia during involution of the enlarged organ. Virchows Arch. B. 1971; 9: 125-34.
3. Argyris TS, Magnus DR. The stimulation of liver growth and demethylase activity following phenobarbital treatment. Dev. Biol. 1968; 17: 187-201.
4. Reddy JK, Lalwani ND. Carcinogenesis by hepatic peroxisome proliferators: Evaluation of the risk of hypolipidemic drugs and industrial plasticizers to humans. Crit. Rev. Toxicol. 1983; 12: 1-58.
5. Columbano A, Ledda GM, Sirigu P, Perra T, Pani P. Liver cell proliferation induced by a single dose of lead nitrate. Am. J. Pathol. 1983; 110: 83-8.
6. Ledda-Columbano GM, Columbano A, Faa G, Pani P. Lead and liver cell proliferation. Effect of repeated administrations. Am. J. Pathol. 1983; 113: 315-20.
7. Schuhe-Hermann R. Induction of liver growth by xenobiotic compounds and other stimuli. Grit. Rev. Toxicol. 1974; 3: 97-158.
8. Bursch W, Lauer B, Timmermann-Trosiener I, Barthel G, Schuppler J, Schulte-Hermann R. Controlled death (apoptosis) of normal and putative preneoplastic cells in rat liver following withdrawal of tumor promoters. Carcinogenesis 1984; 5: 453-8.
9. Roberts RA, Soames AR, Gill JH, James NH, Wheeldon EB. Non-genotoxic hepatocarcinogens stimulate DNA synthesis and their withdrawal induces apoptosis, but in different hepatocyte populations, Carcinogenesis 1995; 16: 1693-8.
10. Columbano A, Ledda-Columbano GM, Coni PP et al. Occurrence of cell death (apoptosis) during the involution of liver hyperplasia. Lab. Invest. 1985; 52: 670-5.
11. 1 as a signal for induction of cell death by apoptosis. Br. J. Cancer 1993; 67: 531-6.
12. 1. Proc. Natl Acad. Sci. USA 1992; 89: 5408-12.
13. 1, within 5 hours in regressing liver without significant fragmentation of the DNA. Hepatology 1993; 18: 1238-46.
14. 1 gene expression and insulin-like growth factor II/mannose-6-phosphate receptor gene expression in rat liver. Carcinogenesis 1994; 15: 419-21.
15. Higgins GM, Anderson RM. Experimental pathology of the liver: Restoration of the liver of the white rat following partial surgical removal. Arch. Pathol. 1931; 12: 186-202.
16. 3. Cancer Res. 1962; 22: 842-9.
17. Bucher NLR, Malt RA. Regeneration of liver and kidney. Boston: Little Brown, 1971.
18. Zarnegar R, DeFrances MC, Kost DP, Lindroos P, Michalopoulos GK. Expression of hepatocyte growth factor mRNA in regenerating rat liver after partial hepatectomy. Biochem. Biophys. Res. Commun. 1991; 177: 559-65.
19. Kinoshita T, Hirao S, Matsumoto K, Nakamura T. Possible endocrine control by hepatocyte growth factor after partial hepatectomy. Biochem. Biophys. Res. Commun. 1991; 177: 330-5.
20. Webber EM, FitzGerald MJ, Brown PI, Bartlett MH, Fausto N.Transforming growth factor-α expression during liver regeneration after partial hepatectomy and toxic injury, and potential interactions between transforming growth factor-α and hepatocyte growth factor. Hepatology 1993; 18: 1422-31.
21. Evarts RP, Nakatsukasa H, Marsden ER, Hu Z,Thorgeirsson SS. Expression of transforming growth factor-alpha in regenerating liver and during hepatic differentiation. Mol. Carcinog. 1992; 5: 25-31.
22. 1 and type I procollagen transcripts during regeneration and early fibrosis of rat liver. Lab. Invest. 1990; 63: 171-80.
23. Jakowlew SB, Mead JE, Danielpour D, Wu J, Roberts AB, Fausto N. Transforming growth factor-β (TGF-β) isoforms in rat liver regeneration: Messenger RNA expression and activation of latent TGF-β. Cell. Regul. 1991; 2: 535-48.
24. Russell WE, Coffey RJ Jr, Ouellette AJ, Moses HL. Type β transforming growth factor reversibly inhibits the early proliferative response to partial hepatectomy in the rat. Proc. Natl Acad. Sci. USA 1988; 85: 5126-30.
25. Schackert HK, Fan D, Fidler IJ. Transient inhibition of liver regeneration in mite by transforming growth factor-beta 1 encapsulated in liposomes. Cancer Commun. 1990; 2: 165-71.
26. Nakamura T, Tomita Y, Hirai R, Yamaoka K, Kaji K, Ichihara A. Inhibitory effect of transforming growth factor-β on DNA synthesis of adult rat hepatocytes in primary culture, Biochem. Biophys. Res. Commun. 1985; 133: 1042-50.
27. Carr BI, Hayashi I, Branum EL, Moses HL. Inhibition of DNA synthesis in rat hepatocytes by platelet-derived type β transforming growth factor. Cancer Res. 1086; 46: 2330-4.
28. Shima N, Nagao M, Ogaki F, Tsuda E, Murakami A, Higashio K. Tumor cytotoxic factor/hepatocyte growth factor from human fibroblasts: Cloning of its cDNA, purification and characterization of recombinant protein. Biochem. Biophys. Res. Commun. 1994; 200: 808-15.
29. Fujiwara K, Nagoshi S, Ohno A et al. Stimulation of liver growth by exogenous human hepatocyte growth factor in normal and partially hepatectomized rats. Hepatology 1993; 18: 1443-9.
30. Liu ML, Mars WM, Zarnegar R, Michalopoulos GK. Collagenase pretreatment and the mitogenic effect of hepatocyte growth factor and transforming growth factor-α in adult rat liver. Hepatology 1994; 19: 1521-7.
31. Webber EM, Godovvski PJ, Fausto N. In vivo response of hepatocytes to growth factors requires an initial priming stimulus. Hepatology 1994; 19: 489-97.
32. Roos F, Ryan AM, Chamow SM, Bennett GL, Schwall RH. Induction of liver growth in normal mice by infusion of hepatocyte growth factor scatter factor. Am. J. Physiol. 1995; 268: G380-6.
33. Sato Y, Fujiwara K. Compensatory route of spermidine acetylation and oxidation can supply sufficient putrescine for hepatic DNA synthesis at an early stage after partial hepatectomy in diaminopropane-treated rats. J. Biochem. 1988; 104: 98-101.
34. Gavrieli Y, Sherman Y, Ben-Sasson SA. Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. J. Cell Biol. 1992; 119: 493-501.
35. Chomczynski P, Sacchi N. Single-step method of RNA isolation by acid guanidium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 1987; 162: 156-9.
36. Qian SW, Kondaiah P, Roberts AB, Sporn MB. cDNA cloning by PCR of rat transforming growth factor β-1. Nucleic Acids Res. 1900; 18: 3050.
37. Tso JY, Sun X-H, Kao T-H, Reece KS, Wu R. Isolation and characterization of rat and human glyceraldehyde-3-phosphate dehydrogenase cDNAs: Genomic complexity and molecular evolution of the gene. Nucleic Acids Res. 1985; 13: 2485-502.
38. Ishiki Y, Ohnishi H, Muto Y, Matsumoto K, Nakamura T. Direct evidence that hepatocyte growth factor is a hepatotrophic factor for liver regeneration and has a potent antihepatitis effect in vivo. Hepatology 1092; 16: 1227-35.
39. Grasl-Kraupp B, Ruttkay-Nedecky B, Koudelka H, Bukowaka K, Bursch W, Schulte-Hermann R. In situ detection of fragmented DNA (TUNEL assay) fails to discriminate among apoptosis, necrosis, and autolytic cell death: A cautionary note. Hepatology 1995; 21: 1465-8.
40. Bursch W, Taper HS, Lauer B, Schulte-Hermann R. Quantitative histological studies on the occurrence and stages of controlled cell death (apoptosis) during regression of rat liver hyperplasia. Virchows Arch. Cell. Pathol. 1985; 50: 153-66.
41. Bursch W, Paffe S, Putz B, Barthel G, Schulte-Hermann R. Determination of the length of the histological stages of apoptosis in normal liver and in altered hepatic foci of rats. Carcinogenesis 1990; 11: 847-53.
42. Bursch W, Dusterberg B, Schulte-Hermann R. Growth, regression and cell death in rat liver as related to tissue levels of the hepatomitogen cyproterone acetate. Arch. Toxicol. 1986; 59: 221-7.
43. Wheeldon EB, Williams SM, Soames AR, James NH, Roberts RA. Quantitation of apoptotic bodies in rat liver by in situ end labelling (ISEL): Correlation with morphology. Toxicol. Pathol. 1995; 23: 410-15.
44. Yasuda H, Imai E, Shiota A, Fujise N, Morinaga T, Higashio K. Antifibrogenic effect of a deletion variant of hepatocyte growth factor on liver fibrosis in rats. Hepatology 1996; 24: 636-42.
45. 1 in the parenchymal cells of the liver accompanied by an enhanced sensitivity to undergo apoptosis and necrosis without inflammation. Hepatology 1996; 23: 329-37.
46. Bissell DM, Wang S, Jarnagin WR, Roll FJ. Cell-specific expression of transforming growth factor-β in rat liver. Evidence for autocrine regulation of hepatocyte proliferation. J. Clin. Invest. 1995; 96: 447-55.