Dietary protein level regulates expression of the mitochondrial branched-chain aminotransferase in rats

Journal of Nutrition

Volumn 128, Issue 8, 1998, Pages 1368-1375

  Torres, Nimbe ^a   López, Gabriel ^a   De Santiago, Soledad ^a   Hutson, Susan M ^b   Tovar, Armando R ^a  

^a INSTITUTO NACIONAL DE CIENCIAS MÉDICAS Y NUTRICIÓN SALVADOR ZUBIRÁN   (Mexico)

^b WAKE FOREST SCHOOL OF MEDICINE   (United States)

Author keywords

Branched chain aminotransferase; Hormones; Malnutrition; Protein; Rats

Indexed keywords

AMINOTRANSFERASE;

ANIMAL EXPERIMENT; ARTICLE; DIET SUPPLEMENTATION; ENZYME ACTIVITY; ENZYME LOCALIZATION; ENZYME SYNTHESIS; MALE; NONHUMAN; PROTEIN INTAKE; PROTEIN MALNUTRITION; RAT; STOMACH; TISSUE DISTRIBUTION;

EID: 0031830268     PISSN: 00223166     EISSN: None     Source Type: Journal    
DOI: 10.1093/jn/128.8.1368     Document Type: Article

References (50)

1. Adibi, S. A., Peterson, J. A. & Krzysik, B. A. (1975) Modulation of leucine transaminase activity by dietary means. Am. J. Physiol. 288: 432-435.
2. Berlin, C. M. & Schimke, R. T. (1965) Influence of turnover rates on responses of enzymes to cortisone. Mol. Pharmacol. 1: 149-156.
3. Bledsoe, R. K., Dawson, P. A. & Hutson, S. M. (1997) Cloning of the rat and human mitochondrial branched chain aminotransferases (BCATm). Biochim. Biophys. Acta 1339: 9-13.
4. Cappuccino, C., Kadowaki, H. & Knox, E. (1978) Assay of leucine aminotransferase in rat tissues and tumors. Enzyme 23: 328-338.
5. Chan, W. & Waiser, M. (1978) Effect of branched-chain keto-acids and dietary protein content on the activity of branched-chain amino acid transferase in rat tissues. J.Nutr. 108: 40-45.
6. Chomczynski, P. & Sacchi, N. (1987) Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162: 156-159.
7. Crowell, P., Torres, N. & Harper, A. E. (1988) Response of rat liver branched-chain α-keto acid dehydrogenase (BCKAD) to a meal and changes in dietary protein. FASEB J. 2: A1090 (abs.).
8. Davoodi, J., Drown, P. M., Bledsoe, R. K., Wallin, R., Reinhart, G. D. & Hutson, S. M. (1998) Overexpression and characterization of the human mitochondrial and cytosolic branched-chain aminotransferases. J. Biol. Chem. 273:4982-4989.
9. De Santiago, S., Torres, N. Suryawan, A., Tovar, A. R & Hutson, S. M., (1998) Regulation of branched-chain amino acid metabolism in the lactating rat. J. Nutr. (in press).
10. Goto, M., Shinno, H. & Ichihara, A. (1977) Isozyme patterns of branched-chain amino acid transaminase in human tissues and tumors. Gann 68: 663-667.
11. Hall, T. R., Wallin, R., Reinhart, G. D. & Hutson, S. M. (1993) Branched chain aminotransferase isoenzymes: purification and characterization of the rat brain isoenzyme. J. Biol. Chem. 268: 3092-3098.
12. Harper, A. E. (1984a) Biological factors influencing the utilization of amino acids. In: Genetic Factors in Nutrition (Velázquez, A. & Bourges, H., eds.), pp. 243-278. Academic Press, Orlando, FL.
13. Harper, A. E. (1984b) Interrelationships among the branched chain amino acids. International Symposium on Branched Chain Amino and Keto Acids in Health and Disease, pp. 81 -99. Karger, Göttingen, Germany.
14. Harper, A. E., Block, K. P. & Cree, T. C. (1983) Branched-chain amino acids: nutritional and metabolic inter-relationships. 4th International Symposium, Protein Metabolism and Nutrition, pp. 160-181. INRA, Clermont-Ferrand, France.
15. Harper, A. E., Miller, R. H. & Block, K. P. (1984) Branched-chain amino acid metabolism. Annu. Rev. Nutr. 4: 409-454.
16. Heard, C. R., Frangi, S. M., Wright, P. M. & McCartney, P. R. (1977) Biochemical characteristics of different forms of protein-energy malnutrition: an experimental model using young rats. Br. J. Nutr. 37: 1-21.
17. Hutson, S. M. (1988) Subcellular distribution of branched-chain aminotransferase activity in rat tissues. J. Nutr. 118: 1475-1481.
18. Hutson, S. M., Bledsoe, R. K., Hall, T. R. & Dawson, P. A. (1995) Cloning and expression of the mammalian cytosolic branched chain aminotransferase isoenzyme. J. Biol. Chem. 270: 30344-30352.
19. Hutson, S. M., Cree, T. & Harper, A. E. (1978) Regulation of leucine and α-ketoisocaproate metabolism in skeletal muscle. J. Biol. Chem 253: 8126-8133.
20. Hutson, S. M., Fenstermacher, D. & Mahar, C. (1988) Role of mitochondrial transamination in branched chain amino acid metabolism. J. Biol. Chem. 263: 3618-3625.
21. Hutson, S. M., Wallin, R., and Hall, T. R. (1992) Identification of mitochondrial branched chain aminotransferase and its isoforms in rat tissue. J. Biol. Chem. 267:15681-15686.
22. Ichihara, A. (1975) Isozyme patterns of branched-chain amino acid transaminase during cellular differentiation and carcinogenesis. Ann. N.Y. Acad. Sci. 259: 347-354.
23. Ichihara, A. (1985) Aminotransferases of branched-chain amino acids. In: Transaminases (Christen, P. & Metzler, D. E., eds.), vol. 2, pp. 430-499. John Wiley & Sons, New York, NY.
24. Ichihara, A. & Koyama, E. (1966) Transaminase of branched chain amino acids. J. Biochem 59: 160-169.
25. Ichihara, A., Noda, C. & Ogawa, K. (1973) Control of leucine metabolism with special reference to branched-chain amino acid transaminase isozymes. Adv. Enz. Reg. II: 155-166.
26. Ichihara, A., Takahashi, H., Aki, K. & Shirai, A. (1967) Transaminase of branched chain amino acids. II Physiological change in enzyme activity in rat liver and kidney. Biochem. Biophys. Res. Commun. 26: 674-678.
27. Lee, S. C. & Harper, A. E. (1971) Responses of mammalian histidine catabolic enzymes to dietary and hormonal treatments. Biochim. Biophys. Acta 244: 135-145.
28. Lee, S. C., Tews, J. K., Morris, M. L. & Harper, A. E. (1972) Rat liver histidase: glucose repression and half-life after casein hydrolysate feeding. J. Nutr. 102: 319-330.
29. Lunn, P. G., Whitehead, R. G., Hay, R. W. & Baker, B. A. (1973) Progressive changes in serum cortisol, insulin and growth hormone concentrations and their relationship to the distorted amino acid pattern during the development of kwashiorkor. Br. J. Nutr. 29: 399-422.
30. Miller, R. H., Eisenstein, R. S. & Harper, A. E. (1988) Effects of dietary protein intake on branched-chain keto acid dehydrogenase activity of the rat. J. Biol. Chem. 263:3454-3461.
31. Mimura, T., Yamada, C. & Swendseid, M. E. (1968) Influence of dietary protein levels and hydrocortisone administration on the branched-chain amino acid transaminase activity in rat tissues. J. Nutr. 95: 493-498.
32. Morris, M. L., Lee, S. C. & Harper, A. E. (1973) A comparison of the responses of mitochondrial and cytosol histidine-pyruvate aminotransferases to nutritional and hormonal treatments. J.Biol. Chem. 248: 1459-1465.
33. Ogawa, H., Fujioka, M., Su, Y., Kanamoto, R. & Pitot, H. C. (1991) Nutritional regulation and tissue-specific expression of the serine dehydratase gene in rat. J. Biol. Chem. 266: 20412-20417.
34. Oku, H., Yagi, N., Nagata, J. & Chinen, I. (1994) Precursor role of branched-chain amino acids in the biosynthesis of iso and anterso fatty acids in rat skin. Biochim. Biophys. Acta 1214: 279-287.
35. Osifo, B. O. & Bolodeoku, J. O. (1982) Serum aspartate and alanine aminotransferase activities in protein energy malnutrition. Enzyme 28: 300-304.
36. Philbrick, D. J. & Hill, D. C. (1974) Development of malnutrition in rats. Am. J. Clin. Nutr. 27: 813-818.
37. Reeds, P. J. (1974) The catabolism of valine in the malnourished rat. Studies in vivo and in vitro with different labelled forms of valine. Br. J. Nutr. 31: 259-270.
38. Rogers, Q. R. & Harper, A. E. (1965) Amino acid diets and maximal growth in the rat. J. Nutr. 87: 267-273.
39. 14C-labelled branched-chain α-oxo acids. Biochem. J. 126: 445-446.
40. Schimke, R. T. (1970) Regulation of protein degradation in mammalian tissues. In: Mammalian Protein Metabolism (Munro, H. N., ed.), vol. IV, pp. 177-228. Academic Press, New York, NY.
41. Shinnick, F. L. & Harper, A. E. (1976) Branched-chain amino acid oxidation by isolated rat tissue preparations. Biochim. Biophys. Acta 437: 477-486.
42. Taylor, R. T. & Jenkins, W. T. (1966) Leucine aminotransferase. II. Purification and characterization. J. Biol. Chem. 241: 4396-4405.
43. Torres, N., Martinez, L., Alemán, G., Bourges, H. & Touar, A. R. (1998) Histidase expression is regulated by dietary protein at the pretranslational level in rat liver. J. Nutr. 128:818-824.
44. Torres, N., Tovar, A. & Harper, A. (1993) Metabolism of valine in rat skeletal muscle mitochondria. J. Nutr. Biochem. 4: 681-689.
45. Torres, N., Tovar, A. R. & Harper, A. E. (1995) Leucine affects the metabolism of valine by isolated perfused rat hearts: relation to branched-chain amino acid antagonism. J. Nutr. 125: 1884-1892.
46. Tovar, A. R., Tews, J. K., Torres, N. & Harper, A. E. (1988) Some characteristics of threonine transport across the blood-brain barrier of the rat. J. Neurochem. 51: 1285-1293.
47. Tovar, A. R., Tews, J. K., Torres, N. & Harper, A. E. (1991) Neutral amino acid transport into rat skeletal muscle: competition, adaptive regulation, and effects of insulin. Metabolism 40: 410-419.
48. Tovar, A. R., Tews, J. K., Torres, N., Madsen, D. C. & Harper, A. E. (1992) Competition for transport of amino acids into rat heart: effect of competitors on protein synthesis and degradation. Metabolism 41: 925-933.
49. Wohlhueter, R. M. & Harper, A. E. (1970) Co-induction of rat liver branched chain α-keto acid dehydrogenase activities. J. Biol. Chem. 245: 2391-2401.
50. Zhao, Y., Popov, K. M., Shimomura, Y., Kedishvili, N. Y., Jaskiewicz, J., Kuntz, M., Kain, J., Zhang, B. & Harris, R. A. (1994) Effect of dietary protein on the liver content and subunit composition of the branched-chain α-keto acid dehydrogenase complex. Arch. Biochem. Biophys. 308: 446-453.