Cytochrome P-450-dependent arachidonate metabolites and renal functions in the Lyon hypertensive rat

Clinical and Experimental Pharmacology and Physiology

Volumn 25, Issue 7-8, 1998, Pages 559-563

  Messer Letienne I ^a   Bernard, N ^a   Benzoni, D ^a   Sassard, J ^a  

^a UNIVERSITÉ LYON 1   (France)

Author keywords

17 octadecynoic acid; Epoxyeicosatrienoic acids; Hydroxyeicosatetraenoic acids; Hypertension; Isolated perfused kidney; Miconazole; Rat

Indexed keywords

17 OCTADECYNOIC ACID; ARACHIDONIC ACID DERIVATIVE; CYTOCHROME P450; ENZYME INHIBITOR; HYDROXYICOSATETRAENOIC ACID; MICONAZOLE; NORADRENALIN; UNCLASSIFIED DRUG;

ANIMAL MODEL; ANIMAL TISSUE; ARACHIDONIC ACID METABOLISM; ARTICLE; CONTROLLED STUDY; GLOMERULUS FILTRATION RATE; HYPERTENSION; IN VITRO STUDY; MALE; NATRIURESIS; NONHUMAN; RAT; VASCULAR RESISTANCE; VASOCONSTRICTION;

EID: 0031830024     PISSN: 03051870     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1440-1681.1998.tb02251.x     Document Type: Article

References (20)

1. Harder DR, Campbell WB, Roman RJ. Role of cytochrome P-450 enzymes and metabolites of arachidonic acid in the control of vascular tone. J. Vasc. Res. 1995; 32: 79-92.
2. Katoh T, Takahashi K, Capdevila J et al. Glomerular stereospecific synthesis and hemodynamic actions of 8,9-epoxyeicosatrienoic acid in rat kidney. Am. J. Physiol. 1991: 261: F578-86.
3. Takahashi K, Capdevila J, Karara A. Falck JR, Jacobson HR, Badr KF. Cytochrome P-450 arachidonate metabolites in rat kidney: Characterization and hemodynamic responses. Am. J. Phsyiol. 1990; 258: F781-9.
4. + channel activity in renal arterioles. Hypertension 1994; 24: 382 (Abstract).
5. Imig JD, Navar LG, Roman RJ, Reddy K, Falck JR. Actions of epoxygenase metabolites on the preglomerular vasculature. J. Am. Soc: Nephrol. 1996; 7: 2364-70.
6. Makita K, Takahashi K, Karara A, Jacobson HR, Falck JR, Capdevila JH. Experimental and/or genetically controlled alterations of the renal microsomal cytochrome P-450 epoxygenase induce hypertension in rats fed a high salt diet. J. Clin. Invest. 1994; 94: 2414-20.
7. Imig JD, Zou AP, Stec DE, Harder DR, Falck JR, Roman RJ. Formation and actions of 20-hydroxyeicosatetraenoic acid in rat renal arterioles. Am. J. Physiol. 1996; 270: R217-27.
8. Harder DR, Narayanan Y, Birks EK et al. Identification of a putative microvascular oxygen sensor. Circ. Res. 1996; 79: 54-61.
9. Zou AP, Imig JD, Kaldunski M, Ortiz De Montellano PR, Sui Z, Roman RJ. Inhibition of renal vascular 20-HETE production impairs autoregulation of renal blood flow. Am. J. Physiol. 1994; 266: F275-82.
10. Escalante B, Sacerdoti D, Davidian MM, Laniado-Schwartzman M, McGiff JC. Chronic treatment with tin normalizes blood pressure in spontaneously hypertensive rats. Hypertension 1991; 17: 776-9.
11. Sacerdoti D, Escalante B, Abraham NG, McGiff JC, Levere RD, Schwartzman ML. Treatment with tin prevents the development of hypertension in spontaneously hypertensive rats. Science 1988; 243: 388-90.
12. Imig JD, Falck JR, Gebremedhin D, Harder DR, Roman RJ. Elevated renovascular tone in young spontaneously hypertensive rats: Role of cytochrome P-450. Hypertension 1993; 22: 357-64.
13. Stec DE, Deng AY, Rapp JP, Roman RJ. Cytochrome P4504A geno-type cosegregates with hypertension in Dahl S rats. Hypertension 1996; 27: 564-8.
14. Zou AP, Drummond HA, Roman RJ. Role of 20-HETE in elevating loop chloride reabsorption in Dahl SS/Jr rats. Hypertension 1996; 27: 631-5.
15. Liu KL, Hadj Aissa A, Lareal MC, Benzoni D, Vincent M, Sassard J. Adrenergic stimulation of renal prostanoids in the Lyon hypertensive rat. Hypertension 1991; 17: 296-302.
16. Zou AP, Ma YH, Sui ZH et al. Effect of 17-octadecynoic acid, a suicide-substrate inhibitor of cytochrome P-450 fatty acid ω-hydroxylase, on renal function in rats. J. Pharmacol. Exp. Ther. 1994; 268: 474-81.
17. Campbell WB, Gebremedhin D, Pratt PF, Harder DR. Identification of epoxyeicosatrienoic acids as endothelium-derived hyperpolarizing factors. Circ. Res. 1996; 78: 415-23.
18. Dudek RR, Conforto A, Pinto V, Wildhirt S, Suzuki H. Inhibition of endothelial nitric oxide synthase by cytochrome P-450 reductase inhibitors. Proc. Soc. Exp. Biol. Med. 1995; 209: 60-4.
19. Bogle RG, Whitley GS, Soo SC, Johnstone AP, Vallance P. Effect of antifungal imidazoles on mRNA levels and enzyme activity of inducible nitric oxide synthase. Br. J. Pharmacol. 1994; 111: 1257-61.
20. Steinhilber D, Jaschonek K, Knospe J, Morof O, Roth HJ. Effects of novel antifungal azole derivatives on the 5-lipoxygenase and cyclooxygenase pathway. Arzneimittelforschung 1990; 40: 1260-3.