Selective serotonin reuptake inhibitors may enhance responses to noxious stimulation

Pharmacology Biochemistry and Behavior

Volumn 60, Issue 3, 1998, Pages 719-725

  Dirksen, Ris ^a   Van Luijtelaar, E L J M ^a   Van Rijn, C M ^a  

^a RADBOUD UNIVERSITY NIJMEGEN   (Netherlands)

Author keywords

Fluoxetine; Fluvoxamine; Nociception; Noxious induced withdrawal reflex

Indexed keywords

FLUOXETINE; FLUVOXAMINE; MORPHINE; SEROTONIN UPTAKE INHIBITOR; TRICYCLIC ANTIDEPRESSANT AGENT;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD PRESSURE; DOSE RESPONSE; DRUG ACTIVITY; DRUG EFFECT; ELECTROSTIMULATION THERAPY; INTRAVENOUS DRUG ADMINISTRATION; MALE; NOCICEPTION; NONHUMAN; PAIN ASSESSMENT; PRIORITY JOURNAL; RAT; SEROTONINERGIC SYSTEM; STATISTICAL ANALYSIS; TAIL FLICK TEST; THERMAL STIMULATION;

ANIMALS; BLOOD PRESSURE; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTRIC STIMULATION; FLUOXETINE; FLUVOXAMINE; HEART RATE; HEAT; MALE; PAIN; PAIN MEASUREMENT; RATS; RATS, WISTAR; REACTION TIME; SEROTONIN UPTAKE INHIBITORS;

EID: 0031829596     PISSN: 00913057     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0091-3057(98)00030-6     Document Type: Article

References (64)

1. Bardin, L.; Bardin, M.; Lavarenne, J.; Eschalier, A.: Effect of intrathecal serotonin on nociception in rats: Influence of the pain test used. Exp. Brain Res. 113:81-87; 1997.
2. Beasly, C. M.; Dornseif, B. E.; Bosomworth, J. C.; Sayler, M. E.; Rampey, A. H., Jr. Heiligenstein, J. H.; Thompson, V. L.; Murphy, D. J.; Masica, D. N.: Fluoxetine and suicide: A meta-analysis of controlled trials of treatment for depression. Br. Med. J. 303: 685-692; 1991.
3. Beasly, C. M.; Masica, D. N.; Potvin, J. H.: Fluoxetine: A review of receptor and functional effects and their clinical implications. Psychopharmacology (Berlin) 107:239-248; 1992.
4. Belcher, G.; Ryall, R. W.; Schaffner, R.: The differential effects of 5-hydroxytryptamine, noradrenaline and raphe stimulation on nociceptive and non-nociceptive dorsal horn interneurones in the cat. Brain Res. 151:307-321; 1978.
5. Berge, O. G.: Effects of 5-HT receptor agonists and antagonists on a reflex response to radiant heat in normal and spinally transected rats. Pain 13:253-266; 1982.
6. Bowker, R. M.; Abbott, L. C.: Quantitative re-evaluation of descending serotonergic and non-serotonergic projections from the medulla of the rodent: Evidence for extensive co-existence of serotonin and peptides in the same spinally projecting neurons, but not from the nucleus raphe magnus. Brain Res. 512:15-25; 1990.
7. Boyer, W. F.; Feighner, J. P.: The efficacy of selective serotonine inhibitors in depression. In: Feighner, J. P.; Boyer, W. F., eds. Selective serotonine uptake inhibitors. Chichester, UK: Wiley; 1991:89-109.
8. Butler, S.: Present status of tricyclic antidepressants in chronic pain therapy. In: Benetti, C., ed. Advances in pain research and therapy, vol. 7. New York: Raven Press; 1984:173-198.
9. Choi, A.; Mitchelson, F.: Variation in the affinity of amitriptyline for muscarinic receptor subtypes. Pharmacology 48:293-300; 1994.
10. Coquoz, D.; Porchet, H. C.; Dayer, P.: Central analgesic effects of desipramine, fluvoxamine, and moclobemide after single oral dosing: A study in healthy volunteers. Clin. Pharmacol. Ther. 54: 339-344; 1993.
11. DeFelipe, M. C.; DeCeballos, M. L.; Fuentes, J. A.: Hypoalgesia induced by antidepressants in mice: A case for opioids and serotonin. Eur. J. Pharmacol. 125:193-199; 1986.
12. Dickenson, A. H.; LeBars, D.: Diffuse noxious inhibitory controls involve trigeminothalamic and spinothalamic neurones in the rats. Exp. Brain Res. 49:174-180; 1983.
13. Dirksen, R.; VanDePol, F.; Nijhuis, G. M. M.: Control of the sensory input into the spinal cord. In: Nijhuis, G. M. M., ed. Anesthesiology, feedback and feedforward. Nijmegen, The Netherlands: Nijmegen University Press; 1988:97-111.
14. Dirksen, R.; Lerou, J. G. C.; Nijhuis, G. M. M.; Booij, L. H. D. J.: Intrathecal naloxone but not pentazocine reverses the effect of intravenous morphine in rats. Eur. J. Anaesth. S3:15-23; 1990.
15. Dirksen, R.; Lerou, J. G. C.; Nijhuis, G. M. M.; Booij, L. H. D. J.: The effects of pentazocine, morphine and naloxone on a withdrawal reflex elicited with noxious transcutaneous electrical stimulation. Eur. J. Anaesth. S3:23-41; 1990.
16. Dirksen, R.; Lagerwerf, A. J.; Vree, T. B.; Lerou, J. G. C.; Nijhuis, G. M. M.; Booij, L. H. D. J.: Plasma concentrations of pentazocine and its reflex suppressive effects in rats kept under urethane anesthesia. Eur. J. Anaesth. S3:41-49; 1990.
17. Dirksen, R.; Lerou, J. G. C.; Lagerwerf, A. J.; Vree, T. B.; Nijhuis, G. M. M.; Booij, L. H. D. J.; Jurna, I.: A small animal model for pharmacological studies of general anesthetic agents. Eur. J. Anaesth. 7:285-298; 1990.
18. Dirksen, R.: Analgesiology: A new approach to pain. In: Parris, W. C. V., ed. Contemporary issues in chronic pain treatment. Norwell: Kluwer Academic Press; 1991;33-50.
19. Dirksen, R.; Lerous, J.; Bakker, H.; VanLuijtelaar, E.; Nijhuis, G.; Gielen, M.; Booij, L.: The dose-response and time-effect relationships of intrathecal bupivacaine in rats. The influence of epinephrine and pH. Acta Anaesthesiol. Scand. 36:153-158; 1992.
20. Dirksen, R.; VanDiejen, D.; VanLuijtelaar, E. L. J. M.; Booij, L. H. D. J.: Site- and test-dependent antinociceptive efficacy of amitriptyline in rats. Pharmacol. Biochem. Behav. 47:21-26; 1994.
21. Dreshfield, L. J.; Wong, D. T.; Perry, K. W.; Engleman, E. A.: Enhancement of fluoxetine-dependent increase of extracellular serotonin (5-HT) levels by (-)-pinodolol, an antagonist at 5-HT1A receptors. Neurochem. Res. 21:557-562; 1996.
22. Echizen, H.; Freed, C. R.: Long-term infusion of L-5-hydroxytryptophan increases brain serotonine turnover and decreases blood pressure in normotensive rats. J. Pharmacol. Exp. Ther. 220:579-584; 1982.
23. Eisenach, J. C.; Gebhart, G. F.: Intrathecal amitryptiline acts as an N-methyl-D-aspartate receptor antagonist in the presence of inflammatory hyperalgesia in rats. Anesthesiology 83:1046-1054; 1995.
24. Fields, H. L.; Basbaum, A. I.: Brainstem control of spinal transmission neurons. Annu. Rev. Physiol. 40:193-221; 1978.
25. Glowinski, J.; Axelrod, J.: Inhibition of uptake of tritiated-noradrenaline in the intact rat brain by imipramine and structurally related compounds. Nature 204:1318-1319; 1964.
26. Gordon, N. C.; Heller, P. H.; Gear, R. W.; Levine, J. D.: Interactions between fluoxetine and opiate analgesia for postoperative dental pain. Pain 58:85-88; 1964.
27. Griersmith, B. T.; Duggan, A. W.: Prolonged depression of spinal transmission of nociceptive information by 5-HT administered in the substantia gelatinosa: Antagonism by methysergide. Brain Res. 187:231-236; 1980.
28. Hall, H.; Sällemark, M.; Wedel, I.: Acute effects of atypical anti-depressants on various receptors in the rat brain. Acta Pharmacol. Toxicol. 54:379-384; 1984.
29. Hwang, A. S.; Wilcox, G. L.: Analgesic properties of intrathecally administered heterocylic antidepressants. Pain 28:343-355; 1987.
30. Invernizzi, R.; Belli, S.; Samanin, R.: Citalopram's ability to increase the extracellular concentrations of serotonin in the dorsal raphe prevents the drug's effect in the frontal cortex. Brain Res. 584:322-324; 1992.
31. Jeftinija, S.; Raspantini, C.; Randic, M.; Yaksh, T. L.; Go, V. L. W.; Larson, A. A.: Altered responsiveness to substance P and 5-hydroxytryptamine in cat dorsal horn after 5-HT depletion with p-chlorophenylalanine. Brain Res. 368:107-115; 1986.
32. Jordon, J. M.; Kenshalo, D. R., Jr.; Martin, J. F.; Willis, W. D.: Two populations of spinothalamic tract neurons with opposite responses to 5-hydroxytryptamine. Brain Res. 164:342-346; 1979.
33. Kanof, P. D.; Greengard, P.: Brain histamine receptors as targets for antidepressant drugs. Nature 272:329-333; 1978.
34. Kessler, K. A.: Tricyclic antidepressants: Mode of action and clinical use. In: Lipton, M. A.; Dimascio, A.; Killam, K. F., eds. Psychopharmacology: A generation of progress. New York: Raven Press; 1978:1289-1303.
35. Krstic, M. K.; Djurkovic, D.: Comparison of the cardiovascular responses to intracerebroventricular administration of tryptamine, 5-hydroxytryptamine, tryptophan and 5-hydroxytryptophan in rats. Arch. Int. Physiol. Biochim. 89:385-591; 1981.
36. Kuraishi, Y.; Harada, Y.; Satoh, M.; Tagaki, H.: Antagonism by phenoxybenzamine of the analgesic effect of morphine injected into the nucleus reticularis gigantocellularis of the rat. Neuropharmacology 18:107-111; 1979.
37. Kuraishi, Y.; Harada, Y.; Aratani, S.; Satoh, M.; Tagaki, H.: Separate involvement of the spinal noradrenergic and serotonergic systems in morphine analgesia: The difference in mechanical and thermal algesic tests. Brain Res. 273:245-252; 1983.
38. LeBars, D.; Dickenson, A. H.; Besson, J. M.: Diffuse noxious inhibitory controls (DNIC). I. Effects on dorsal horn convergent neurons in the rat. Pain 6:283-304; 1979.
39. LeBars, D.; Dickenson, A. H.; Besson, J. M.: Diffuse noxious inhibitory controls (DNIC). II. Lack of effect on nonconvergent neurons, supraspinal involvement and theoretical inplications. Pain 6:305-327; 1979.
40. LeBars, D.; Bouhassira, D.; Villanueva, L.: Opioids and diffuse noxious inhibitory controls (DNIC) in the rat. In: Bromm, B.; and Desmedt, J. E., eds. Advances in pain treatment, vol. 20. Pain and the brain. New York: Raven Press; 1995:517-541.
41. Magni, G.; Conlon, P.; Arsie, D.: Tricyclic antidepressants in the treatment of cancer pain: A review. Pharmacopsychiatry. 20:160-164; 1987.
42. Max, M. B.; Lynch, S. A.; Muir, J.; Shoaf, S. E.; Smoller, B.; Dubner, R.: Effects of desipramine, amitriptyline, and fluoxetine on pain in diabetic neuropathy. N. Engl. J. Med. 326:1250-1256; 1992.
43. Pape, H. C.; McCormick, D. A.: Noradrenaline and serotonine selectively modulate thalamic burst firing by enhancing a hyperpolarization-activated cation current. Nature 340:715-718; 1989.
44. Romano, J. M.; Turner, J. A.: Chronic pain and depression: Does the evidence support a relationship? Psychol. Bull. 97:18-34; 1985.
45. 14C-5-hydroxytryptamine in slices and crude synaptosome preparations of the midbrain-hypothalamus region of the rat brain. Acta Pharmacol. Toxicol. 36:382-394; 1975.
46. Rutter, J. J.; Gundlah, C.; Auerbach, S. B.: Increase in extracellular serotonin produced by uptake inhibitors is enhanced after chronic treatment with fluoxetine. Neurosci. Lett. 25:183-186; 1994.
47. Saper, J. R.; Silberstein, S. D.; Lake, A. E., Jr.; Winters, M. E.: Double-blind trial of fluoxetine: Chronic daily headache and migraine. Headache 34:497-502; 1994.
48. Sindrup, S. H.; Gram, L. F.; Brsen, K.; Eshj, O.; Mogensen, E. F.: The selective serotonine reuptake inhibitor paroxetine is effective in the treatment of diabetic neuropathy symptoms. Pain 42: 135-145; 1990.
49. Sugrue, M. F.: On the role of 5-hydroxytryptamine in drug-induced antinociception. Br. J. Pharmacol. 65:677-681; 1979.
50. Tjølsen, A.; Berge, O.-G.; Eide, P. K.; Broch, O. J.; Hole, K.: Apparent hyperalgesia after lesions of the descending serotonergic pathways is due to increased tail skin temperature. Pain 33: 225-231; 1988.
51. Todd, A. J.; Millar, J.: Receptive fields and responses to iontophretically applied noradrenaline and 5-hydroxytryptamine of units recorded in lamina I-III of cat dorsal horn. Brain Res. 288: 159-167; 1983.
52. Tura, B.; Tura, S. M.: The analgesic effect of tricyclic antidepressants. Brain Res. 518:19-22; 1990.
53. VanderLaan, J. W.; Dirksen, R.: Dipropylacetate-induced shaking behavior in the rat: The role of adrenergic receptors at the spinal level. Eur. J. Pharmacol. 152:197-205; 1988.
54. Vasko, R.; Pang, I. H.; Vogt M.: Involvement of 5-hydroxytryptamine-containing neurons in antinociception produced by injection of morphine into nucleus raphe magnus or onto spinal cord. Brain Res. 306:341-348; 1984.
55. Walsh, T. D.: Antidepressants in chronic pain, Review. Clin. Neuropharmacol. 6:271-295; 1983.
56. Weight, F. F.; Salmoiraghi, G. C.: Responses of spinal cord inter-neurones to acetylcholine, norepinephrine and serotonine administered by iontophoresis. J. Pharmacol. Exp. Ther. 153:420-427; 1966.
57. Wessendorf, M. W.; Eide, R.: The coexistence of serotonin- and substance P-like immunoreactivity in the spinal cord of the rat as shown by immunofluorescent double labeling. J. Neurosci. 7: 2352-2363; 1987.
58. Willis, W. D., Jr.: Modulation of primate spinothalamic tract discharges. In: Kruger, L.; Liebeskind, J. C., eds. Advances in pain research, vol. 6. Neural mechanisms of pain. New York: Raven Press; 1984: 217-241.
59. Wolfe, F.; Cathey, M. A.; Hawley, D. J.: A double-blind placebo controlled trial of fluoxetine in fibromyalgia. Scand. J. Rheumatol. 23:255-259; 1994.
60. Wolff, A.; Dirksen, R.; Gielen, M. J. M.; Booij, L. H. D. J.: The intrathecal effectiveness of four short acting local anesthetics in rats: A single concentration response relationship. Regul. Anesth. 18:2S; 1993.
61. Wong, D. T.; Horng, J. S.; Bymaster, F. P.; Hauser, K. L.; Molloy, B. B.: A selective inhibitor of serotonin uptake: Lilly 110140, 3-(p-trifluoromethylphenoxy)-N-methyl-3-phenylpropylamine. Life Sci. 15:471-479; 1974.
62. Yaksh, T. L.: Direct evidence that spinal serotonine and noradrenaline terminals mediate the spinal antinociceptive effects of morphine in the periaqueductal gray. Brain Res. 160:180-185; 1978.
63. Yaksh, T. L.; Wilson, P. R.: Spinal serotonine terminal system mediates antinociception. J. Pharmacol. Exp. Ther. 208:446-453; 1979.
64. York, J. L.; Maynert, E. W.: Alterations in morphine analgesia produced by chronic deficits of brain catecholamines or serotonin: Role of analgesimetric procedure. Psychopharmacology (Berlin) 56:119-125; 1978.