Blood and cerebral concentrations of the new potential analgesic UP 26- 91 measured in vivo by microdialysis after toxic boses

Arzneimittel-Forschung/Drug Research

Volumn 48, Issue 7, 1998, Pages 745-749

  Bouër, Ronan ^a,b   Saivin, Sylvie ^a,b   Malmary, Marie France ^a   Hermann, Philippe ^c   Poey, Jacques ^a   Houin, Georges ^a,b  

^a UNIVERSITÉ DE TOULOUSE   (France)

^b CHU RANGUEIL   (France)

^c UPSA Laboratories   (France)

Author keywords

(3 2 4 (2,4 Difluoro)piperazin 1 yl ethyl thio 1,2,4 triazolo 4,3 a pyrioline, citrate salt; CAS 115762 17 9; UP 26 91, brain and jugular microdialysis, pharmacokinetics

Indexed keywords

3 [[2 [4 (2,4 DIFLUOROPHENYL)PIPERAZIN 1 YL]ETHYL]THIO] 1,2,4 TRIAZOLO[4,3 A]PYRIOLINE CITRATE; ANALGESIC AGENT; UNCLASSIFIED DRUG;

ANALGESIA; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; BRAIN CORTEX; DRUG ABSORPTION; DRUG BLOOD LEVEL; DRUG BRAIN LEVEL; DRUG DISPOSITION; DRUG DOSAGE FORM; DRUG ELIMINATION; DRUG EXPOSURE; DRUG TISSUE LEVEL; MICRODIALYSIS; NONHUMAN; RADIOACTIVITY; RAT; STATISTICAL ANALYSIS;

ANALGESICS, NON-NARCOTIC; ANIMALS; BRAIN; INFUSIONS, INTRAVENOUS; MALE; MICRODIALYSIS; PIPERAZINES; RATS; RATS, SPRAGUE-DAWLEY; TRIAZOLES;

EID: 0031829405     PISSN: 00044172     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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