Adjuvant postoperative radiation therapy +/- 5-FU in resected carcinoma of the pancreas

Hepato-Gastroenterology

Volumn 45, Issue 21, 1998, Pages 613-623

  Foo, May L ^a   Gunderson, Leonard L ^b  

^a MAYO CLINIC   (United States)

^b MAYO CLINIC ROCHESTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; FLUOROURACIL;

ARTICLE; CANCER ADJUVANT THERAPY; CANCER CONTROL; CANCER SURVIVAL; DIARRHEA; HUMAN; LEUKOPENIA; MUCOSA INFLAMMATION; NAUSEA; PANCREAS ADENOCARCINOMA; PANCREAS RESECTION; PANCREATICODUODENECTOMY; PRIORITY JOURNAL; TREATMENT FAILURE; UNITED STATES; VOMITING;

ADENOCARCINOMA; CHEMOTHERAPY, ADJUVANT; CLINICAL TRIALS; COMBINED MODALITY THERAPY; FLUOROURACIL; HUMANS; INTRAOPERATIVE PERIOD; PANCREATIC NEOPLASMS; RADIOTHERAPY, ADJUVANT; RANDOMIZED CONTROLLED TRIALS; RETROSPECTIVE STUDIES; SURVIVAL RATE; TREATMENT OUTCOME;

EID: 0031828982     PISSN: 01726390     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (38)

1. Parker S, Tong T, Bolden S, Wingo P. Cancer Statistics, 1996. CA Cancer journal for clinicians. 996; 46(1):5-27.
2. National Cancer Institute. Annual cancer statistics review 1973-1988. Bethesda, Md. Department of Health and Human Services, 1991. (NIH publication no. 91-2789.)
3. Connolly MM, Dawson PJ, Michelassi F, Moosa AR, Lowenstein F. Survival in 1001 patients with carcinoma of the pancreas. Ann Surg. 1987; 206:366-73.
4. Moertel CG, Frytak S, Hahn RG, et al. Therapy of locally unresectable pancreatic carcinoma: a randomized comparison of high dose (6000 rads) radiation alone, moderate dose radiation (4000 rads + 5-fluorouracil), and high dose radiation + 5-fluorouracil: the Gastrointestinal Tumor Study Group. Cancer. 1981; 48:1705-10.
5. Gunderson LL, Willett CG. Pancreas and hepatobiliary tract. In: Perez CA, Brady LW, eds. Principles and Practice of Radiation Oncology. Philadelphia, Pa: JB Lippincott. 1992; 985-99.
6. Kaiser MH, Ellenberg, SS. Pancreatic cancer: adjuvant combined radiation and chemotherapy following curative resection: the Gastrointestinal Tumor Study Group. Arch Surg. 1985; 120:899-903.
7. Cubilla AL, Fitzgerald PJ, Fortner JG. Pancreas cancer -duct cell adenocarcinoma: survival in relation to site, size, stage and type of therapy. J Surg Oncol 1978; 10:465-82.
8. Nagai H, Kuroda A, Morioka Y. Lymphatic and local spread of T1 and T2 pancreatic cancer. Ann Surg 1986; 204:65-71.
9. Rosenberg JM, Welch JP, Macaulay WP. Cancer of the head of the pancreas: an institutional review with emphasis on surgical therapy. J Surg Oncol 1985; 28:217-21.
10. Tsuchiya R, Noda T, Harada M, et al. Collective review of small carcinomas of the pancreas. Ann Surg. 1986; 203:77-81.
11. Funovics JM, Karner J, Pratschner T, Fritsch A. Current trends in the management of carcinoma of the pancreatic head. Hepato-Gastroenterology 1989; 36:450-5.
12. Singh SM, Longmire WP Jr., Reber HA. Surgical palliation for pancreatic cancer: the UCLA experience. Ann Surg 1990; 212:132-9.
13. Warshaw AL, Gu Z-Y, Wittenberg J, Waltman AC. Preoperative staging and assessment of resectability of pancreatic cancer. Arch Surg. 1990; 125:230-3
14. Warshaw AL, Tepper J, Shipley. Laparoscopy in the staging and planning of therapy for pancreatic cancer. The Am J Surgery 1986; 151:76-80.
15. Trede M, Schwall G, Saeger HD. Survival after pancreatoduodenectomy. Ann Surg 1990; 211:447-58.
16. Cameron JL, Crist DW, Sitzmann JV, et al. Factors influencing survival after pancreaticoduodenectomy for pancreatic cancer. Am J Surg 1991; 161:120-5.
17. van Heerden JA, McIlrath DC, Ilstrup DM, Weiland LH. Total pancreatectomy for ductal adenocarcinoma of the pancreas: an update. World J Surg. 1988; 12:658-62.
18. Gudjonsson B. Cancer of the pancreas: 50 years of surgery. Cancer. 1987; 60:2284-303.
19. Gudjonsson B, Livstone EM, Spiro HM. Cancer of the pancreas: diagnosic accuracy and survival statistics. Cancer. 1978; 42:2494-506.
20. Brooks JR, Brooks DC, Levine JD. Total pancreatectomy for ductal cell carcinoma of the pancreas: an update. Ann Surg 1989; 209:405-10.
21. van Heerden J, ReMine WH, Weiland LH, McIlrath DC, Ilstrup DM. Total pancreatectomy for ductal adenocarcinoma of the pancreas. Am J Surg 1981; 142:308-11.
22. Andren-Sandberg A, Ihse I. Factors influencing survival after total pancreatectomy in patients with pancreatic cancer. Ann Surg. 1983; 198:605-10.
23. Sarr M, Behrns K, van Heerden J. Total pancreatectomy. Hepato-Gastroenterology. 1993; 40:418-421.
24. Warshaw AL, Castillo CF. Pancreatic carcinoma. New England J Medicine. 1992; 326:455-65.
25. Yeo C, Cameron J, Lillemoe K, Sitzmann J, Hruban R, Goodman S, Dooley W, Coleman J, Pitt H. Pancreaticoduodenectomy for cancer of the head of the pancreas. Annals of Surgery. 1995; 221; 6:721-733.
26. Willet C, Lewandrowski K, Warshaw A, Efird J, Compton C. Resection margins in carcinoma of the head of the pancreas. Annals of Surgery. 1993; 217;2:144-148.
27. Tepper J, Nardi G, Suit H. Carcinoma of the pancreas: review of MGH experience farom 1963 to 1973. Cancer. 1976;37:1519-24.
28. Griffin JT, Smalley SR, Jewell W, Paradelo JC, Reymond RD, Hassanein RES, Evans RG. Patterns of failure after curative resection of pancreatic carcinoma. Cancer 1990; 66:56-61.
29. Gastrointestinal Tumor Study Group. Further evidence of effective adjuvant combined radiation and chemotherapy following curative resection of pancreatic cancer. Cancer. 1987;59:2006-2010.
30. Foo ML, Gunderson LL, Nagorney DM, McIlrath DC, van Heerden JA, et al Patterns of failure in grossly resected pancreatic ductal adenocarcinoma treated with adjuvant irradiation + 5 fluorouracil. Int J Radiation Oncology Biol Phys 1993; 26:483-89.
31. Whittington R, Bryer M, Haller D, Solin L, Rosato E. Adjuvant therapy of resected adenocarcinoma of the pancreas. Int J Radiat Oncol Biol Phys 1991; 21:1137-1143.
32. Davis B, Raben A, Casper E, Minsky B. Acute toxicity and efficacy of postoperative combined modality therapy for adenocarcinoma of the pancreas. Int. J. Radiation Oncology Biol Phys. 1996; 36(1)Supp. Abstract 2039: 297.
33. Bosset J, Pavy J, Gillet M, Mention G, Pelissier E, Schraub S. Conventional external irradiation alone as adjuvant treatment in resectable pancreatic cancer: results of a prospective study. Radiotherapy and oncology. 1992; 24:191-194.
34. Johnstone P, Sindelar W. Lymph node involvement and pancreatic resection: Correlation with prognosis and local disease control in a clinical trial. Pancreas. 1993; 5:535-539.
35. Sindelar WF, Kinsella TJ. Randomized trial of intraoperative radiotherapy in resected carcinoma of the pancreas. Int J Radiation Oncology Biol Phys 1986;12:148.
36. Kinsella TJ, Sindelar WF. Intraoperative radiotherapy for pancreatic carcinoma. Cancer. 1996, 78(3 supp): 598-604.
37. Fossati V, Cattanco G, Zerbi A, Galli L, Bordogne G, Reni M, Parolini D, Carrlucci M, Bissi A, Standacher C, DiCarlo V, Calandrino R. The role of intraoperative therapy by electron beam and combination of adjuvant chemotherapy and external radiotherapy in carcinoma of the pancreas. Tumori. 1995;81:23-31.
38. Rich T. Radiation therapy for pancreatic cancer: eleven year experience at the JCRT. 1985; 11:759-763.